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Entacom Plus 100 Tablet

Levodopa (100mg)+ Carbidopa (25mg)+ Entacapone (200mg)

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Entacom Plus 100 Tablet is a prescription medicine used in the treatment of Parkinson's disease. This medicine helps to reduce excessive shaking by slowing down the body movements. It works by increasing the amount of chemical messenger that is needed to control abnormal movements.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)

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General Information

Contains

Levodopa (100mg)+ Carbidopa (25mg)+ Entacapone (200mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Entacom Plus 100 Tablet is taken with or without food, but better to avoid high protein meal and dairy products. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it can result in harmful effects.

This medicine may cause side effects like nausea, diarrhea, vomiting, constipation, discoloration of urine, and dryness in the mouth. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is common to have diarrhea with this medicine, so drink plenty of fluids and watch for weight loss.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Entacom Plus Tablet

Parkinson's disease

Benefits of Entacom Plus Tablet

Parkinson's disease
Entacom Plus 100 Tablet is a medicine that helps relieve symptoms of Parkinson's disease such as tremors, muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Side effects of Entacom Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Entacom Plus

Nausea
Vomiting
Diarrhea
Urine discoloration
Headache
Dryness in mouth
Insomnia (difficulty in sleeping)
Anxiety
Dizziness
Abnormal dreams
Involuntary muscle movement
Gastrointestinal disturbance

How to use Entacom Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Entacom Plus 100 Tablet may be taken with or without food.
Avoid Entacom Plus 100 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How Entacom Plus Tablet works

Entacom Plus 100 Tablet is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinson’s disease.

All substitutes for Entacom Plus 100 Tablet

For information purposes only. Consult a doctor before taking any medicine.

SynCAPONE 100 Tablet

by Sun Pharmaceutical Industries Ltd

₹13/tablet

1% cheaper

Quick tips

You have been prescribed Entacom Plus 100 Tablet to treat your symptoms of parkinson's disease.
Avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking this medicine as that can reduce the amount of medication absorbed by your body.
It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Do not stop taking the medication suddenly without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating and confusion.
Talk to your doctor in case you develop hallucinations or notice other changes in your behavior.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Entacom Plus 100 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Entacom Plus 100 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Entacom Plus 100 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Entacom Plus 100 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Entacom Plus 100 Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Entacom Plus 100 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Entacom Plus 100 Tablet used for?

Entacom Plus 100 Tablet is used to treat symptoms of Parkinson’s disease, such as stiffness, shaking, and movement difficulties. It helps improve mobility by increasing dopamine levels in the brain.

Who should not take Entacom Plus 100 Tablet?

Individuals should not take Entacom Plus 100 Tablet if they have narrow-angle glaucoma or are taking certain antidepressants called nonselective MAO inhibitors. It is advised to always check with your doctor before starting this medicine.

Can Entacom Plus 100 Tablet cause drowsiness or sudden sleep attacks?

Yes. Entacom Plus 100 Tablet can make some people feel very sleepy and, in rare cases, may cause sudden sleep episodes without warning. If this happens, avoid driving, operating machinery, or doing activities that require alertness.

What are the serious side effects of Entacom Plus 100 Tablet?

Serious side effects of Entacom Plus 100 Tablet include severe muscle pain, confusion, high fever, hallucinations, suicidal thoughts, uncontrolled movements, severe diarrhea, or signs of muscle breakdown such as dark urine. Seek medical attention immediately if these occur.

Can Entacom Plus 100 Tablet affect my blood pressure?

Yes. Entacom Plus 100 Tablet can lower blood pressure, especially when standing up from a seated or lying position, which may cause dizziness or fainting. This is called orthostatic hypotension. Getting up slowly can help reduce the risk.

Does Entacom Plus 100 Tablet increase the risk of mental health problems?

Some patients may experience depression, suicidal thoughts, hallucinations, or unusual behaviors such as gambling, overeating, or increased sexual urges during Entacom Plus 100 Tablet treatment. If you notice mood or behavior changes, inform your doctor immediately.

Can Entacom Plus 100 Tablet cause digestive or bowel problems?

Yes. Entacom Plus 100 Tablet may cause diarrhea, sometimes severe. If you develop persistent diarrhea or abdominal pain, contact your doctor right away.

Are there special precautions for people with stomach ulcers or eye problems before taking Entacom Plus 100 Tablet?

Yes. People with a history of peptic ulcers may be at risk of bleeding, and those with narrow-angle glaucoma must avoid Entacom Plus 100 Tablet. Always inform your doctor if you have these conditions.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

References

User feedback

Patients taking Entacom Plus 100 Tablet

Four Times A Day

80%

Thrice A Day

20%

What are you using Entacom Plus Tablet for?

Parkinson's disease

100%

How much was the improvement?

Excellent

67%

Average

33%

What were the side-effects while using Entacom Plus 100 Tablet?

Sleepiness

100%

Please rate Entacom Plus 100 Tablet on price

Not Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Entacom Plus 100 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Entacom Plus 100 Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Entacom Plus Tablet

Benefits of Entacom Plus Tablet

Side effects of Entacom Plus Tablet

How to use Entacom Plus Tablet

How Entacom Plus Tablet works

All substitutes for Entacom Plus 100 Tablet

SynCAPONE 100 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Entacom Plus 100 Tablet used for?

Who should not take Entacom Plus 100 Tablet?

Can Entacom Plus 100 Tablet cause drowsiness or sudden sleep attacks?

What are the serious side effects of Entacom Plus 100 Tablet?

Can Entacom Plus 100 Tablet affect my blood pressure?

Does Entacom Plus 100 Tablet increase the risk of mental health problems?

Can Entacom Plus 100 Tablet cause digestive or bowel problems?

Are there special precautions for people with stomach ulcers or eye problems before taking Entacom Plus 100 Tablet?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Entacom Plus 100 Tablet

What are you using Entacom Plus Tablet for?

How much was the improvement?

What were the side-effects while using Entacom Plus 100 Tablet?

Please rate Entacom Plus 100 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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