Levodopa + Carbidopa + Entacapone
Information about Levodopa + Carbidopa + Entacapone
Levodopa + carbidopa + entacapone uses
Levodopa+Carbidopa+Entacapone is used in the treatment of Parkinson's disease.
How levodopa + carbidopa + entacapone works
This is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinson’s disease.
Common side effects of levodopa + carbidopa + entacapone
Nausea, Vomiting, Constipation, Discoloration of urine, Headache, Dryness in mouth, Insomnia (difficulty in sleeping), Orthostatic hypotension (sudden lowering of blood pressure on standing), Anxiety, Dizziness, Abnormality of voluntary movements, Abnormal dreams