food interaction for SYNCAPONE

alcohol interaction for SYNCAPONE

pregnancy interaction for SYNCAPONE

lactation interaction for SYNCAPONE

Avoid Syncapone 100 tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.
Syncapone 100 tablet may cause excessive drowsiness and calmness with alcohol.
Syncapone 100 tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Syncapone 100 tablet is probably unsafe to use during breastfeeding. Please consult your doctor.




Levodopa is used in the treatment of parkinson's disease.

How it works

Levodopa works by being converted to dopamine, a chemical messenger that is needed to control the movement through transmission of signals in the brain.

Common side effects

Nausea, Vomiting, Dizziness, Loss of appetite, Orthostatic hypotension (sudden lowering of blood pressure on standing), Movement disorder.


Carbidopa is used in the treatment of parkinson's disease.

How it works

Carbidopa is always given with levodopa. It works by preventing levodopa from being broken down before it reaches the brain. This allows for a lower dose of levodopa, which causes less nausea and vomiting.

Common side effects

Nausea, Neuroleptic malignant syndrome, Panic attacks, Altered behaviour, Mood changes, Altered sleep, Burning sensation of tongue, Confusion, Convulsion, Dizziness, Drowsiness, Fever, Frequent dreams, Hallucination, Increased sweating, Tachycardia, Irregular heart rate, Tremor, Vomiting, Worsening of tremor, Muscle stiffness.


Entacapone is used in the treatment of parkinson's disease.

How it works

Entacapone works by increasing the amount of dopamine, a chemical messenger that is needed to control movements in the brain.

Common side effects

Nausea, Vomiting, Fatigue, Confusion, Angina pectoris, Constipation, Insomnia (difficulty in sleeping), Nightmare, Hallucination, Increased sweating, Fall, Abnormality of voluntary movements, Urine discolouration.


Patients taking SYNCAPONE 100 TABLET

  • 27%
    Four Times A Day
  • 27%
    Thrice A Day
  • 21%
    Twice A Day
  • 19%
    Once A Day
  • 4%
    Twice A Month
  • 1%
    Alternate Day


2 Substitutes
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Expert advice FOR SYNCAPONE

  • If you are taking carbidopa with levodopa, do not take iron salts (eg, ferrous sulfate), within 2 hours before or a diet that is high in protein.
  • Avoid vitamin products that contain vitamin B6 (pyridoxine). This vitamin may reduce the effectiveness of levodopa.
  • Do not use levodopa, if you are allergic to levodopa or any other ingredient.
  • Do not use levodopa, if you have narrow-angle glaucoma; if you are suffering from malignant melanoma (a type of cancer); skin cancer or you have any unusual moles; severe mental disorder.
  • Do not take levodopa, if you have a history of fits (convulsions); heart problems or blood pressure problems; asthma or other lung problems; liver or kidney problems; blood or hormone (endocrine) problems; depression or any other psychiatric disorder; ulcer in your gut or have vomited blood or stomach or intestinal bleeding.
  • If you are undergoing any tests for urine glucose or urine ketones, levodopa may cause the results of some tests to be wrong.
  • Levodopa may cause drowsiness, dizziness, light-headedness or sudden sleep. Do not drive or use machinery while using it.
  • Do not take alcohol along with levodopa.

Frequently asked questions FOR SYNCAPONE


Q. Is levodopa a controlled substance/ a narcotic/ addictive/ lipid soluble/ a dopamine agonist/ a prodrug/ a monoamine oxidase inhibitor (MAOI)/ toxic/ an anticholinergic?
Levopoda is a lipid soluble prodrug that gets converted into dopamine when it crosses the blood brain barrier. It is not a dopamine agonist, controlled substance, narcotic, MAOI, toxic or anticholinergic. It may cause addiction in some patients
Q. Does levodopa work/ stop tremors?
Levodopa is used to treat the symptoms of Parkinson's disease which includes tremors (shaking), stiffness, and slowness of movement. It works in most patients if taken at recommended dosage and duration
Q. Does levodopa cause dyskinesia/ dementia/ accelerate Parkinson's disease/ get you high/stop cause constipation/ urine discoloration?
Levopoda may cause side effects such as constipation, a feeling of high in some patients
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Q. Does levodopa help with balance?
As levodopa helps in controlling tremors,it can improve balancing in patients.


Q. What is carbidopa used for/ what does carbidopa treat/ Is carbidopa a dopamine agonist/ a monoamine oxidase inhibitor (MAOI)/ addictive/ a blood thinner?
Carbidopa is used in combination with other drug levodopa to treat symptoms associated with Parkinson disease and parkinsonism-like symptoms caused by other conditions. It is neither a dopamine agonist, nor a MAOI. It can be addictive and cause blood thinning in some patients
Q. Is carbidopa levodopa/ Is carbidopa levodopa a controlled substance/ a MAOI/ a narcotic/ is carbidopa-levodopa addiction?
Carbidopa works by helping levodopa to reach the brain. It is not a controlled substance, a MAOI, a narcotic. Some people may get addicted to carbidopa levodopa treatment for experiencing better sense of well-being
Q. How does carbidopa effect levodopa?
Carbidopa prevents conversion of levodopa to dopamine in the bloodstream, providing a larger amount of levodopa to relieve symptoms of Parkinson's disease
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Q. Does carbidopa get you high/lower blood pressure/cause hallucinations/cause constipation?
Carbidopa can get some people high, it can cause side effects such as low blood pressure, hallucinations and constipation
Q. Does carbidopa cross the blood brain barrier?
Carbidopa itself cannot cross the blood brain barrier but it allows peripheral levodopa in doing so
Q. How does carbidopa affect the on-off phenomenon?
Patients treated with levodopa therapy for Parkinson's disease may develop motor fluctuations characterized by end-of-dose failure, peak dose dyskinesia, and akinesia. The advanced form of motor fluctuations ('on-off’ phenomenon) is characterized by unpredictable swings from mobility to immobility. Although the causes of the motor fluctuations are not completely understood, in some patients they may be attenuated by treatment regimens that produce steady plasma levels of levodopa
Q. What does carbidopa levodopa look like?
Carbidopa levopoda is basically available in circular, oval or elliptical form and in different colors and sizes which varies for different brands.


Q. Is entacapone a dopamine agonist?
No, entacapone is not a dopamine agonist
Q. Is entacapone a controlled substance?
Yes, entacapone is a controlled substance and may not be available OTC
Q. Does entacapone cross the bbb?
No, entacapone does not cross the blood brain barrier
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Q. Does entacapone lower blood pressure?
No, entacapone does not lower blood pressure.


How effective is this medicine?

Moderately effective


Content on this page was last updated on 23 June, 2017, by Dr. Varun Gupta (MD Pharmacology)