Medicine Overview of Endoxan Injection
Fever, Blood in urine, Hair loss, Urinary tract infection, Mucosal inflammation, Decreased white blood cell count (neutrophils), Infection, Bone-marrow suppression.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Endoxan Asta 200mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.
In Depth Information on Endoxan Injection
- Monitor your blood counts with the help of regular blood tests while on treatment with cyclophosphamide.
- Contact your doctor immediately if you experience difficulty in urinating, blood in urine or any other bladder/ kidney related problems while on treatment with cyclophosphamide.
- Do not start treatment with cyclophosphamide if you are planning to receive any vaccine or if you have a surgery scheduled or you have had a surgical removal of the adrenal glands.
- Take precautions as treatment with cyclophosphamide severely affects your immune system, increasing susceptibility to infections (e.g. pneumonia).
- Caution must be exercised during use of cyclophosphamide in very ill patients, patients with kidney/liver disorders, lung problems and heart problems (related to QT prolongation and abnormal heartbeats).
Endoxan Injection related warnings
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Endoxan Asta 200mg Injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Endoxan Asta 200mg Injection is unsafe to use during lactation.
Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Do not drive unless you are feeling well.
Endoxan Asta 200mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Endoxan Asta 200mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan Asta 200mg Injection may be needed. Please consult your doctor.
Endoxan Asta 200mg Injection should be used with caution in patients with liver disease. Dose adjustment of Endoxan Asta 200mg Injection may be needed. Please consult your doctor.
Frequently asked questions about Endoxan Injection
It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)
Yes. Endoxan is administered in the inactive form (prodrug) and gets converted to active form which has anti-cancer properties
No. Endoxan does not have any specific boxed warning. Please discuss with your doctor about all the possible side effects and warnings relating to use of Endoxan
No. Endoxan comes in a dry powder form that be reconstituted to make a solution for injection or oral liquid as directed
Yes. Endoxan is chemotherapy and a cytotoxic drug used in the treatment of various cancers
No. Endoxan is an alkylating agent used in the treatment of various cancers. It is not an antimetabolite or anthracycline type of anti-cancer drug. It has a structure and effects different from steroids
Endoxan is an irritant and can cause tissue inflammation at site of injection if its oozes out of the vein
Yes. Hair loss (alopecia), infertility (in men and women), low platelet count (thrombocytopenia), headaches and inflammation of the urinary bladder (hemorrhagic cystitis) are among the known common side effects of Endoxan use
Endoxan is unlikely to be removed by plasma exchange since a very low percentage of drug is bound to proteins in the plasma.
Severely interacts with other drugs like
Taking Endoxan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
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One of the following vendor pharmacies will deliver Endoxan Asta 200mg Injection: BBS, SRG, ABP, DPL, CLT, ATP, SVH, AMR, UMP, JVO, NVY, JVN, MAK, GPT, SSA, ANT, AGT, ENP, DLP, RSA, SBL, BIO, VRS, HPC, OWP, HMP, OIP, AAY, PEN, TOM, DGN, TNH, MAX, KHH, USF, HBV, SHD, BDN, STA, PPR, SCH, SGC, HEX, LCC, GBL, SAF, RPP, JIV, DFP, OHM, ZEL, SDM, PVP, PLT, HAT, NVL, PNT, PTI, MPC, GNC, RSS, AVN, SWA, NSL, OLT, THP, MDO, SWP, JMJ, IAD, SYN, PRN, MMS, SAT, BMJ, RJH, RUS, LHA, EQN, RWP, SJP, WSI, HIP, ADT, NWP, ZVP, GPP, NNH, DPP, RKS, ARD, ATL, MAM, 9T9, NXG, RHW, SBA, BHP, BAL, AYU, PWN, SHP, MLC, DDR, FGH, GTK, EMB, MOM, RHL, AAR, INC, BTM, IPL, DYG, MSD, HGI, TRP, NTB, DHR, GTC, WHL, NDP, BSN