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02 Mar 2020 | 05:28 PM (IST)
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Endoprost 250 Injection


Overview

Introduction

Endoprost 250 Injection is a medicine used to control excessive bleeding from the uterus, that may occur after the childbirth. It stimulates contraction of the uterine muscles thus, helps to control post-delivery bleeding.

Endoprost 250 Injection is given as an injection deep into the muscles under the medical supervision of a doctor. It is only given at the hospital sitting, so do not self- administered the medicine. The dose and how often you take it depends on what you are taking it for.  You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include vomiting, flushing, hot flushes, headache, and chills. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. If you notice dizziness, avoid driving or attention seeking activity.

Before taking this medicine, tell your doctor if you have ever had heart disease, or you have high or low blood pressure or have liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Always remember, it is only giver after delivery not during pregnancy.

Uses of Endoprost Injection

Side effects of Endoprost Injection

Common
  • Vomiting
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache
  • Nausea
  • Chills
  • Diarrhea
  • Placental retention
  • Cough

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Flushing (sense of warmth in the face, ears, neck and trunk)
    Sip cold or iced drinks. Try cutting down on coffee, tea and alcohol. It might help to keep the room cool and use a fan. You could also spray cool water on your face. Wear layers of light clothing that you can easily take off if you overheat. Breathe deeply and try to relax. Have a lukewarm shower or bath instead of a hot one. Avoid smoking and cut down on alcohol. The flushing should go away after a few days. If it does not go away or causes problems, contact your doctor. There may be medicines that can help.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Cough
    Get plenty of rest as exhausting or stressing out yourself could aggravate your condition. You should drink plenty of fluids as it will keep your throat moist and comfortable. Try taking steam inhalation. The moisture can ease your breathing and loosen mucus. You can consider sipping warm water or tea with honey and lemon. This will keep your nose and throat from being too dry. Using an air humidifier may also help. You can also gargle with salt water several times a day. See your doctor if your symptoms last longer than 3 weeks or get worse quickly. Avoid alcohol and do not smoke as they can aggravate your conditions.

How to use Endoprost Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Endoprost Injection works

Endoprost 250 Injection stimulates contraction of the uterine muscles, helping to control post-delivery bleeding.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Endoprost 250 Injection. Please consult your doctor.
Pregnancy
UNSAFE
Endoprost 250 Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
CAUTION
Endoprost 250 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Endoprost 250 Injection may cause side effects which could affect your ability to drive.
As Endoprost 250 Injection may make you lose consciousness, feel dizzy or drowsy and this may affect your ability to drive
Kidney
CAUTION
Endoprost 250 Injection should be used with caution in patients with kidney disease. Dose adjustment of Endoprost 250 Injection may be needed. Please consult your doctor.
Use of Endoprost 250 Injection is not recommended in patients with active kidney disease.
Liver
CAUTION
Endoprost 250 Injection should be used with caution in patients with liver disease. Dose adjustment of Endoprost 250 Injection may be needed. Please consult your doctor.
Use of Endoprost 250 Injection is not recommended in patients with active liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Endoprost 250 Injection
₹144.0/ml of Injection
Evacarb 250mcg Injection
Celon Laboratories Ltd
₹120/ml of Injection
save 17%
₹151/ml of Injection
5% costlier
₹161.2/ml of Injection
12% costlier
Caboprost 250mcg Injection
Neon Laboratories Ltd
₹211.8/ml of Injection
47% costlier
Cystos 250mcg Injection
Vhb Life Sciences Inc
₹642.85/Injection
346% costlier

Quick Tips

  • Endoprost 250 Injection increases the contraction of your womb which helps to control excessive bleeding after delivery.
  • It is injected deep in to a muscle by your doctor or nurse.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It may cause an increase in body temperature. This will return to normal few hours after the last injection.
  • Inform your doctor if you have problems with your heart, lung, kidney or liver.

Patient Concerns

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My doctor ask me to take vit k injection. I am 35 week pregnant. Why this injection is necessary?
Dr. Megha Tuli
Obstetrics and Gynaecology
Your blood must be showing some abnormal results regarding clotting. This injections are given to prevent excessive bleeding during delivery
Lower back pain post delivery.
Dr. Akshat Goel
Orthopaedics
Do Hot fomentation and Apply Dynapar QPS spray Take Tab Myospas-D twice daily and Cap Nurokind-Gold twice daily and Cap Pansec-DSR once daily empty stomach for 4 days
arrow
Do you have any questions related to Endoprost 250 Injection ?

FAQs

Q. What is Endoprost and what is it used for?

Endoprost is an injectable preparation which contains Carboprost. It is used to control excessive bleeding from the uterus that may occur after childbirth. It is used only when other methods or medicines fail to work. It may also be used in the medical abortion of pregnancy between 13th and 20th weeks of gestation.

Q. How and in what dose can it be used?

It is given as an injection, only at a hospital or clinic by the medical healthcare professional. The dose is decided by the doctor, depending on the severity of bleeding after delivery.

Q. What may be the possible side effects associated with it?

The most common side effects include vomiting, nausea, diarrhea, flushing, and headache. You may also feel increased uterine contractions, for some time. However, these conditions are manageable in hospital settings.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 208-209.
  2. Medscape. Carboprost. [Accessed 03 Apr. 2019] (online) Available from:External Link
  3. Carboprost tromethamine. New York, New York: Pharmacia & Upjohn Co.; 2013. [Accessed 06 Feb. 2019] (online) Available from:External Link
  4. Carboprost. Sandwich, Kent: Pfizer Limited; 1996 [revised Oct. 2013]. [Accessed 03 Apr. 2019] (online) Available from:External Link
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17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
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