Enamide 250mg Tablet
Prescription Required
Product introduction
Enamide 250mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
Enamide 250mg Tablet is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Enamide 250mg Tablet is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Uses of Enamide Tablet
Benefits of Enamide Tablet
In Tuberculosis (TB)
Enamide 250mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Enamide Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Enamide
- Loss of appetite
- Nausea
- Vomiting
- Gastric irritation
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Weakness
- Depression
- Sleepiness
How to use Enamide Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Enamide 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Enamide Tablet works
Enamide 250mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Enamide 250mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Enamide 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Enamide 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Enamide 250mg Tablet may cause side effects which could affect your ability to drive.
Enamide 250mg Tablet may cause side effects such as drowsiness or a headache, that can impair your ability to drive.
Enamide 250mg Tablet may cause side effects such as drowsiness or a headache, that can impair your ability to drive.
Kidney
SAFE IF PRESCRIBED
Enamide 250mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Enamide 250mg Tablet may not be needed in these patients. Please consult your doctor.
Dose adjustment may be needed in patients with end stage kidney disease.
Dose adjustment may be needed in patients with end stage kidney disease.
Liver
CAUTION
Enamide 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Enamide 250mg Tablet may be needed. Please consult your doctor.
Use of Enamide 250mg Tablet is not recommended in patients with the severe liver disease.
Use of Enamide 250mg Tablet is not recommended in patients with the severe liver disease.
What if you forget to take Enamide Tablet?
If you miss a dose of Enamide 250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Enamide 250mg Tablet
₹9.62/Tablet
Ethide Tablet
Lupin Ltd
₹14.35/tablet
49% costlier
Ethomid Tablet
Macleods Pharmaceuticals Pvt Ltd
₹16.1/tablet
67% costlier
Myobid 250 Tablet
Panacea Biotec Pharma Ltd
₹15.6/tablet
62% costlier
Ethio 250mg Tablet
Concept Pharmaceuticals Ltd
₹16/tablet
66% costlier
Thiomid E 250mg Tablet
United Biotech Pvt Ltd
₹12.27/tablet
28% costlier
Quick tips
- Enamide 250mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
- It has to be taken for several months in order for it work properly (usually 6 months).
- Take it with food to avoid stomach upset.
- It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
- Avoid consuming alcohol while taking this medication.
- Do not stop taking Enamide 250mg Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.
Fact Box
Chemical Class
Nicotinic acid derivatives
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Mycobacterial cell wall inhibitors-Ethambutol
Interaction with drugs
Taking Enamide with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Ethionamide may reduce blood levels of Cycloserine.
Careful consideration is advised when taking Cycloserine with Ethionamide. If concurrent use is essential, watch out for sympto
Ethionamide may reduce blood levels of Isoniazid.
Caution is advised when taking Isoniazid with Ethionamide. If concurrent use is essential, please consult your doctor.
Patient concerns
FAQs
What is Enamide 250mg Tablet? What is it used for?
Enamide 250mg Tablet is an antibiotic. It is used as a second-line medicine in combination with other anti-tuberculosis medicines for the treatment of all forms of tuberculosis caused by Mycobacterium tuberculosis.
Why is Enamide 250mg Tablet called a second line drug?
Tuberculosis (TB) is a difficult infection to treat and when it is detected for the first time, first-line drugs are used. Generally, the appropriate use of first-line drugs (e.g. isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin) can effectively cure TB. But, if the patient does not respond to first-line medicines, then second-line medicines (e.g. Enamide 250mg Tablet, kanamycin, ciprofloxacin, etc.) are used. Second-line medicines have more side effects and are the second choice in terms of effectiveness.
Are there any precautions that I should take while taking Enamide 250mg Tablet so that I respond to the treatment?
It is very important that you take the medicine exactly as directed by your doctor. Your doctor will prescribe at least two more medicines to be taken with Enamide 250mg Tablet. Take all the prescribed medicines as per the instructions and do not miss or stop the treatment on your own. Missing doses and stopping the treatment without consulting the doctor are the major causes of treatment failure and drug resistance (not responding to the medication).
For how long do I need to take Enamide 250mg Tablet?
Your doctor will decide the duration of your treatment depending upon your response to the treatment. The doctor will observe your maximum improvement by evaluating you clinically as well as your blood tests.
Why has my doctor asked me to get blood tests done regularly?
The blood tests are done to check if your liver is functioning properly or not, since Enamide 250mg Tablet may affect your liver. Enamide 250mg Tablet can also alter your blood glucose levels and thyroid hormone levels. Therefore, monitoring is required.
What are the symptoms which are suggestive of liver toxicity caused by Enamide 250mg Tablet?
If you develop symptoms such as loss of appetite, nausea, jaundice (yellowing of the skin and eye white), dark urine, discolored stools, pain and tenderness in the upper right abdomen, inform your doctor immediately. These could be the signs of liver toxicity.
Is it necessary to take pyridoxine with Enamide 250mg Tablet?
Pyridoxine is vitamin B6 that helps to prevent nerve damage, which may occur with the use of Enamide 250mg Tablet. The symptoms of nerve damage are numbness, tingling, or pain in your hands or feet.
My friend is taking Enamide 250mg Tablet and other medicines for TB. I have noticed that sometimes she acts very aggressively. Is it because of the disease or the treatment?
These changes could be due to Enamide 250mg Tablet or other medicines that she is taking for TB. Enamide 250mg Tablet may cause depression, confusion, aggression, abnormal thinking, and even hallucinations. You should speak to her family or doctor and help her out.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1561-562.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 513-14.
- Ethionamide. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2016. [Accessed 19 Jun. 2019] (online) Available from:
- Drugs.com. Ethionamide. [Accessed 01 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Shree Ganesh Pharmaceuticals
Address: 542, 1/10 Bhuta Niwas. Dr Ambekdar Road, PB No 6617, Matunga (E), Mumbai 400019.
Country of origin: India
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