Empazio SM 10+100+1000 Tablet ER

Sitagliptin (100mg)+ Metformin (1000mg)+ Empagliflozin (10mg)

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Empazio SM 10+100+1000 Tablet ER is a medicine used to treat type 2 diabetes mellitus. It works by lowering sugar production and improving insulin action. It also removes excess glucose, helping maintain better blood sugar control.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 27 Aug 2026 | 01:02 AM (IST)

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General Information

Contains

Sitagliptin (100mg)+ Metformin (1000mg)+ Empagliflozin (10mg)

Marketer

Torrent Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Empazio SM 10+100+1000 Tablet ER should be taken exactly as prescribed. It can be taken with or without food. Regular dosing is important to keep blood sugar under control. Do not skip doses or stop without medical advice, as this may cause uncontrolled diabetes. If a dose is missed, take it as soon as remembered, but do not double the dose.

The most common side effects include hypoglycaemia, headache, thirst, constipation, increased urination, and urinary tract infection. Some patients may experience low blood sugar when taken with insulin or sulfonylureas. Rarely, dehydration, excessive thirst, or ketoacidosis may occur.

Empazio SM 10+100+1000 Tablet ER should not be used in patients with severe kidney impairment, end-stage renal disease, or dialysis. It is contraindicated in people with metabolic acidosis or diabetic ketoacidosis. Caution is required in those with a history of frequent urinary or genital infections, dehydration, heart failure, or low blood pressure. It should not be used during pregnancy or breastfeeding unless clearly needed. Regular monitoring of kidney function, blood sugar, and hydration status is advised.

Uses of Empazio SM Tablet ER

Treatment of Type 2 diabetes mellitus

Benefits of Empazio SM Tablet ER

Treatment of Type 2 diabetes mellitus
Type 2 diabetes mellitus is a condition where the body cannot manage blood sugar effectively, leading to persistently high glucose levels. Empazio SM 10+100+1000 Tablet ER helps lower and control blood sugar through complementary actions that improve how the body handles glucose. It helps to maintain stable blood sugar control, reducing the risk of complications and supporting overall health in people with type 2 diabetes.

Side effects of Empazio SM Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Empazio SM

Hypoglycemia (low blood glucose level)
Headache
Increased thirst
Constipation
Frequent urge to urinate
Urinary tract infection

How to use Empazio SM Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Empazio SM 10+100+1000 Tablet ER may be taken with or without food.

How Empazio SM Tablet ER works

Empazio SM 10+100+1000 Tablet ER is a combination of sitagliptin, metformin, and empagliflozin. Metformin decreases glucose production in the liver and improves the body’s response to insulin. Sitagliptin increases insulin release and lowers glucose production after meals by improving natural hormone activity. Empagliflozin helps remove excess glucose through urine by blocking its reabsorption in the kidneys. When combined, these actions complement each other, reducing sugar production, improving insulin action, and promoting glucose elimination. This multi-target approach provides stronger, more balanced blood sugar control and helps lower the risk of long-term complications in type 2 diabetes.

All substitutes for Empazio SM 10+100+1000 Tablet ER

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Stay well hydrated to avoid dehydration and kidney-related problems.
Maintain good personal hygiene to reduce the risk of urinary or genital infections.
Monitor blood sugar levels regularly and attend follow-up checkups.
Inform your doctor immediately if you experience symptoms like extreme thirst, nausea, vomiting, or rapid breathing (possible ketoacidosis).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Empazio SM 10+100+1000 Tablet ER

Pregnancy

CONSULT YOUR DOCTOR

The safety of Empazio SM 10+100+1000 Tablet ER during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Empazio SM 10+100+1000 Tablet ER should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

SAFE

Empazio SM 10+100+1000 Tablet ER does not usually affect your ability to drive.

Kidney

CAUTION

Empazio SM 10+100+1000 Tablet ER should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Empazio SM 10+100+1000 Tablet ER is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What is Empazio SM 10+100+1000 Tablet ER used for?

It is used to manage type 2 diabetes mellitus by helping control blood sugar levels when diet and exercise alone are not enough.

What side effects should I watch for?

Common side effects include urinary or genital infections, frequent urination, or diarrhea. Rarely, serious conditions like ketoacidosis or dehydration may occur.

Can I use Empazio SM 10+100+1000 Tablet ER with insulin?

Yes, but combining with insulin or sulfonylureas may increase the risk of low blood sugar. Your doctor may adjust doses to reduce this risk.

Is Empazio SM 10+100+1000 Tablet ER safe during pregnancy or breastfeeding?

It is not recommended during pregnancy or breastfeeding unless clearly needed. Always consult your doctor before use.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Empagliflozin, sitagliptin, and metformin hydrochloride [Product Information]. Valsad, Gujarat: Torrent Pharmaceuticals Ltd. [Accessed 27 Aug. 2025] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Empazio SM 10+100+1000 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Empazio SM 10+100+1000 Tablet ER

Empazio SM 10+100+1000 Tablet ER

Payment, Returns & Expiry

Cash on delivery

Free Return

Expiry after

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Empazio SM Tablet ER

Benefits of Empazio SM Tablet ER

Side effects of Empazio SM Tablet ER

How to use Empazio SM Tablet ER

How Empazio SM Tablet ER works

All substitutes for Empazio SM 10+100+1000 Tablet ER

Istamet Empa 10/100/1000 Tablet ER

Gibtulio-SM 10/1000 Tablet ER

Empaglyn Trio 10/1000 Tablet ER

Alsita-EM 10/1000 Tablet ER

Sitacip EM 100/10/1000 Tablet ER

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Empazio SM 10+100+1000 Tablet ER used for?

What side effects should I watch for?

Can I use Empazio SM 10+100+1000 Tablet ER with insulin?

Is Empazio SM 10+100+1000 Tablet ER safe during pregnancy or breastfeeding?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests