Sitagliptin + Metformin + Empagliflozin

Last updated 10 Sep 2025 | 08:43 AM (UTC)

Sitagliptin + Metformin + Empagliflozin Uses

Sitagliptin+Metformin+Empagliflozin is used in the treatment of type 2 diabetes mellitus.

How Sitagliptin + Metformin + Empagliflozin works

Sitagliptin + Metformin + Empagliflozin is a combination of sitagliptin, metformin, and empagliflozin. Metformin decreases glucose production in the liver and improves the body’s response to insulin. Sitagliptin increases insulin release and lowers glucose production after meals by improving natural hormone activity. Empagliflozin helps remove excess glucose through urine by blocking its reabsorption in the kidneys. When combined, these actions complement each other, reducing sugar production, improving insulin action, and promoting glucose elimination. This multi-target approach provides stronger, more balanced blood sugar control and helps lower the risk of long-term complications in type 2 diabetes.

Common side effects of Sitagliptin + Metformin + Empagliflozin

Hypoglycemia (low blood glucose level), Headache, Increased thirst, Constipation, Frequent urge to urinate, Urinary tract infection

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Medicine brands for Sitagliptin + Metformin + Empagliflozin

Vicra-SM

Dr. Reddy's Laboratories Ltd.

₹196 to ₹196

1 variant(s)

Empaglyn Trio

Zydus Healthcare Limited

Corona Remedies Pvt Ltd

Torrent Pharmaceuticals Ltd

Abbott Healthcare Pvt Ltd

₹207 to ₹225

2 variant(s)

Empazio SM

Torrent Pharmaceuticals Ltd

₹206 to ₹214

2 variant(s)

Sitabite EM

Corona Remedies Pvt Ltd

₹154 to ₹154

1 variant(s)

Expert advice for Sitagliptin + Metformin + Empagliflozin

Stay well hydrated to avoid dehydration and kidney-related problems.
Maintain good personal hygiene to reduce the risk of urinary or genital infections.
Monitor blood sugar levels regularly and attend follow-up checkups.
Inform your doctor immediately if you experience symptoms like extreme thirst, nausea, vomiting, or rapid breathing (possible ketoacidosis).

Frequently asked questions for Sitagliptin + Metformin + Empagliflozin

Q. What is Sitagliptin+Metformin+Empagliflozin used for?

It is used to manage type 2 diabetes mellitus by helping control blood sugar levels when diet and exercise alone are not enough.

Q. What side effects should I watch for?

Common side effects include urinary or genital infections, frequent urination, or diarrhea. Rarely, serious conditions like ketoacidosis or dehydration may occur.

Q. Can I use Sitagliptin+Metformin+Empagliflozin with insulin?

Yes, but combining with insulin or sulfonylureas may increase the risk of low blood sugar. Your doctor may adjust doses to reduce this risk.

Q. Is Sitagliptin+Metformin+Empagliflozin safe during pregnancy or breastfeeding?

It is not recommended during pregnancy or breastfeeding unless clearly needed. Always consult your doctor before use.