



Duphex Drop
Cefalexin (100mg)
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Duphex Drop is an antibiotic medicine that is given to children for the treatment of a wide range of bacterial infections associated with the ear, nose, throat, tonsils, lungs, and skin. It may also be prescribed as a second line of treatment for urinary tract infections.
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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Duphex Drop
bottle of 10 ml Oral Suspension
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General Information
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Your child’s medicine at a glance
Duphex Drop may be given with or without food. However, if your child develops a stomach upset, prefer giving it with food. It is usually given three times a day but this may vary depending on the type and severity of the infection. Stick to the dose, time, and way prescribed by the doctor. If your child vomits within 30 minutes of taking this medicine, give the same dose again. Avoid giving a double dose if it is almost time for the next dose.
Duphex Drop may cause some minor and temporary side effects such as vomiting, diarrhea, nausea, abdominal pain, and mild skin rash. These side effects usually go away once your child’s body adapts to the medicine. However, if they persist or become bothersome for your child, report to the doctor immediately.
Inform the doctor about your child’s complete medical history, including any previous episode of allergy, heart problems, blood disorders, birth defects, lung anomaly, gastrointestinal problems, skin disorders, and liver or kidney malfunction. This information will help the doctor suggest the correct dose and its related schedule for planning your child’s overall treatment.
Duphex Drop may cause some minor and temporary side effects such as vomiting, diarrhea, nausea, abdominal pain, and mild skin rash. These side effects usually go away once your child’s body adapts to the medicine. However, if they persist or become bothersome for your child, report to the doctor immediately.
Inform the doctor about your child’s complete medical history, including any previous episode of allergy, heart problems, blood disorders, birth defects, lung anomaly, gastrointestinal problems, skin disorders, and liver or kidney malfunction. This information will help the doctor suggest the correct dose and its related schedule for planning your child’s overall treatment.
Uses of Duphex Drop in children
- Treatment of Bacterial infections
- Treatment of Urinary tract infections (UTIs)
- Treatment of Superficial Pyoderma
Benefits of Duphex Drop for your child
Treatment of Bacterial infections
Duphex Drop is an antibiotic medicine that works by killing the infection-causing bacteria in your body. It is effective for bacterial infections of the throat, ears, urinary tract, skin, and soft tissues. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better. Stopping it early may make the infection come back and harder to treat.
Duphex Drop is an antibiotic medicine that works by killing the infection-causing bacteria in your body. It is effective for bacterial infections of the throat, ears, urinary tract, skin, and soft tissues. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better. Stopping it early may make the infection come back and harder to treat.
Side effects of Duphex Drop in children
Duphex Drop does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Duphex
- Abdominal pain
- Diarrhea
- Decreased appetite
- Lethargy
How can I give Duphex Drop to my child?
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Duphex Drop may be taken with or without food.
How Duphex Oral Suspension works
Duphex Drop is an antibiotic. It works by preventing the formation of the bacterial protective covering (cell wall) which is essential for the survival of the bacteria. This activity stops the infection-causing bacteria from growing further and prevents the infection from spreading without making them resistant to further treatment.
All substitutes for Duphex Drop
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply, become resistant, or cause another infection.
- Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
- Contact your doctor if your child has diarrhea that goes on for more than 4 days or if it is severe and watery, or contains blood.
- Conditions like common cold and flu are caused by viruses. This medicine is not to be taken in such cases.
- Only give Duphex Drop to your child for their current infection. Never save medicine for future illnesses.
- Stop this medicine and immediately report to your child’s doctor in case your child develops an itchy rash, facial swelling, or breathing difficulties while taking this medicine.
- You may see white patches inside your child’s mouth and throat after a prolonged intake of Duphex Drop. This could be due to a fungal infection. So, if your child develops any such effect, contact your doctor right away.
- Your doctor has prescribed Duphex Drop to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- Discontinue Duphex Drop and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Your doctor has prescribed Duphex Drop to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- Take it with food to avoid an upset stomach.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Avoid consuming alcohol while taking Duphex Drop as it may cause increased side effects.
- Discontinue Duphex Drop and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Safety advice

Kidney
CAUTION
Duphex Drop should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
SAFE IF PRESCRIBED
Duphex Drop is safe to use in patients with liver disease. No dose adjustment is recommended.
However, consult with your child’s doctor before giving this medicine to your child in case of a severe form of liver disease.
However, consult with your child’s doctor before giving this medicine to your child in case of a severe form of liver disease.
Interaction with drugs
Taking Duphex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Cholera Vaccine (Inactivated) (Oral Route)
Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Cefalexin. Please consult your doctor. Cefalexin may reduce the efficacy of Cholera Vaccine (Inactivated).
Severe
Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)
Cefalexin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Cefalexin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Moderate
Zinc (Oral Route)
Ensure a gap of at least 3 hours between taking Cefalexin and Zinc. Zinc may reduce blood levels of Cefalexin.
Frequently asked questions
A single extra dose of Duphex Drop is unlikely to do any harm. However, if you think you have given too much of Duphex Drop to your child, immediately speak to a doctor. Overdose may cause unwanted side effects and may even worsen your child’s condition.
Yes, Duphex Drop may rarely cause some serious side effects. These may include persistent vomiting, kidney damage, allergy, severe diarrhea, and severe gastrointestinal infections. If your child develops any such unwanted effects, consult your child’s doctor.
Duphex Drop can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Duphex Drop. Also, check with your child’s doctor before giving any medicine to your child.
Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.
Duphex Drop is an antibiotic and its use may affect or compromise the good bacteria in the gastrointestinal tract, thereby increasing the risk of developing other infections. In case your child experiences diarrhea while being on treatment with Duphex Drop, do not abruptly stop the medicine course. Instead, call your child’s doctor to ask about the next steps.
Cephalexin is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Yes, the use of Duphex Drop can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If diarrhea persists, talk to your doctor about it.
Talk to your doctor if Duphex Drop doesn't seem to work for you. Your doctor may increase the dose of Duphex Drop or switch you to an alternate option, which may work for you.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
No, do not stop taking Duphex Drop and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Fact Box
Chemical Class
Cephalosporins
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
First-Generation Cephalosporins
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Durembic Pharma
Address: KOREGAON PARK PUNE411036
Address: KOREGAON PARK PUNE411036
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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