Delivering to Gurgaon
Hi, there!
Login / Sign Up
Buy medicines
Buy health products
Book lab tests
Consult a doctor
1mg Care Plan
Cancer Care
Ayurveda
Partnerships
New
Hindi articles
Offers
All diseases
New
All medicines
Medicines by therapeutic class
Contact us
Need help?
Privacy policy
Return policy
Terms and conditions
Editorial policy
Get more features! Download the app now
Medicine Reminders
Monthly/weekly subscriptions
Health records and analysis
24*7 Emergency services
Download app on the App StoreDownload app on the Google play store
Choose city
Sign in to your account
or
By signing in you agree to our
Terms & conditions
 and 
Privacy policy
sold out tag

Dothichem 25mg Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 04 Jan 2026 | 08:41 PM (IST)
Dothichem 25mg Tablet is a medicine used to treat depression and anxiety. It helps improve mood, reduce feelings of sadness or worry, and restore interest in daily activities. It works by increasing the levels of certain natural chemicals in the brain, which help improve mood and relieve anxiety.
Genuine
Authenticity Assured
Prescription
required
₹74.4 MRP ₹84.3812% off 
 
 
0
footer-icon
All

Save more with additional offers

offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
chevron icon
offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
chevron icon
offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Get cashback up to ₹500
Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.
chevron icon
offer icon
Get upto Rs.150 Cashback
Get upto Rs.150 Cashback
chevron icon

General Information

Contains

Dothiepin (25mg)

Marketer

Swastik India Pvt Ltd
The content is shown in English
Dothichem 25mg Tablet image
Dothichem 25mg Tablet image

Product introduction

Dothichem 25mg Tablet should be taken exactly as prescribed by your doctor. It may be taken with or without food. Take it regularly and take it at the same time every day. Do not stop taking the medicine suddenly without your doctor's advice, as this can cause withdrawal symptoms or worsen your condition. Along with taking the medicine, follow a healthy lifestyle, get enough sleep, and attend regular follow-up appointments.


Some common side effects of Dothichem 25mg Tablet include dry mouth, drowsiness, dizziness, constipation, and weight gain. These usually get better as your body adjusts to the medicine. Drinking plenty of water, eating a high-fibre diet, and avoiding alcohol may help reduce these side effects. If you feel extremely sleepy or dizzy, avoid driving or operating machinery. If any side effects become bothersome or do not go away, let your doctor know.


Before taking Dothichem 25mg Tablet, inform your doctor if you have any heart, liver, or kidney problems, or a history of seizures or glaucoma. This medicine may not be suitable for people with certain medical conditions. Avoid drinking alcohol while taking Dothichem 25mg Tablet, as it can increase drowsiness and worsen side effects. Let your doctor know about all the medicines you are taking, as some medicines may interact with Dothichem 25mg Tablet. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Dothichem Tablet

Benefits of Dothichem Tablet

Treatment of Anxiety
Anxiety is a condition where a person feels constant worry, nervousness, or fear that can interfere with daily activities. Dothichem 25mg Tablet helps calm the mind, reduces excessive worry, and promotes a sense of relaxation. With continued use, it improves sleep, focus, and overall quality of life by reducing the emotional burden of anxiety.
Treatment of Depression
Depression is a mental health condition that causes persistent sadness, low energy, and loss of interest in daily activities. Dothichem 25mg Tablet helps improve mood, boosts emotional well-being, and restores interest in daily life, making it easier to function and cope with everyday challenges. Over time, it brings a sense of stability and positivity to people living with depression.

Side effects of Dothichem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dothichem
  • Dryness in mouth
  • Constipation
  • Weight gain
  • Headache
  • Low sexual desire

How to use Dothichem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dothichem 25mg Tablet may be taken with or without food.

How Dothichem Tablet works

Dothichem 25mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Quick tips

  • Take Dothichem 25mg Tablet at bedtime, as it may cause drowsiness and help improve sleep in people with depression or anxiety.
  • Avoid alcohol while on this medicine, as it can increase sedation and worsen side effects like dizziness or confusion.
  • Inform your doctor if you experience dry mouth, blurred vision, or constipation, as these are common side effects that are usually manageable but should be monitored.
  • Do not stop Dothichem 25mg Tablet suddenly. Your doctor will guide a tailored dose reduction to prevent withdrawal symptoms.
  • Let your doctor know if you have a heart condition, as this medicine can affect heart rhythm, especially in higher doses.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Dothichem 25mg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Dothichem 25mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Dothichem 25mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Dothichem 25mg Tablet may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Dothichem 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Dothichem 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Dothichem 25mg Tablet is a tricyclic antidepressant used to treat major depressive disorder and the anxiety that often comes with it. It works by balancing certain brain chemicals that affect mood. Additionally, it may be used to manage certain types of nerve pain.
Individuals should not take Dothichem 25mg Tablet if they have epilepsy, are recovering from a recent heart attack, or have severe liver problems. Use is also not recommended in those currently taking or who have recently (within the past 14 days) taken MAOI medications. Dothichem 25mg Tablet should be avoided in individuals who are allergic to dothiepin or any of the ingredients present in the formulation.
No, stopping Dothichem 25mg Tablet abruptly may cause withdrawal symptoms like headache, nausea, insomnia, irritability, or even seizures. Your doctor will always taper the dose gradually based on how well you respond to the medicine.
Although rare but serious effects of Dothichem 25mg Tablet include suicidal thoughts especially in young adults, heart arrhythmias, liver problems, seizures, psychosis or mania, etc. If you experience any of these serious side effects, reach out to your doctor at the earliest.
The exact time Dothichem 25mg Tablet takes to work is not known. It may take 2 to 4 weeks to feel the full effect. However, early signs of improvement can occur within the first two weeks. Keep taking it even if you do not feel better right away.
Yes, Dothichem 25mg Tablet may cause suicidal thoughts, particularly in young adults (18 to 24 years of age). Close monitoring is crucial during the first few weeks or after any dose changes. You should report mood changes, agitation, or suicidal thoughts immediately to your doctor or your care taker.
Dothichem 25mg Tablet overdose can be life-threatening with symptoms like irregular heartbeat, seizures, or coma. You should reach out to your doctor immediately if overdose is suspected. Do note that even small overdoses can be fatal.

Fact Box

Chemical Class

Dibenzothiepins

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Tricyclic Antidepressants (TCAs)

References

  1. Dothiepin [Product Information]. NSW, Australia: Viatris; 2022.
Related products
Products related to Dothichem 25mg Tablet
4.4Rating star
Himalaya Mentat Syrup
200 ml Syrup
Get in 60 mins
₹244
₹257
5% off

₹220

order for
₹1200
4.2Rating star
Himalaya Mentat Tablet
60 tablets
Get in 30 mins
₹183
₹206
11% off

₹165

order for
₹1200
4.2Rating star
Dabur Stresscom Ashwagandha Capsule | Manages Fatigue, Weakness & Stress
10 capsules
Get in 30 mins
₹67.2
₹79
15% off

₹60.5

order for
₹1200
4.5Rating star
Aimil Memtone Syrup | Ayurvedic Formula for Complete Mental Wellness, Antistres
200 ml Syrup
Get by 11pm, Today
₹212
₹244
13% off

₹191

order for
₹1200
4.4Rating star
Himalaya Geriforte Syrup
200 ml Syrup
Get in 60 mins
₹219
₹230
5% off

₹197

order for
₹1200
4.1Rating star
Seacod Cod Liver Oil |Omega-3, Vitamins D & A| Immune & Hearth Health | Brain & Joint Support
60 ml Oil
Get in 60 mins
₹235
₹293
20% off

₹212

order for
₹1200
4.3Rating star
Charak Cognium Tablet
20 tablets
Get in 30 mins
₹150

₹135

order for
₹1200
4.8Rating star
Vasu Ranger Syrup
200 ml Syrup
Get by Thu, 23 Apr
₹138
₹141
2% off

₹124

order for
₹1200
Fracbon Tablet
10 tablets
Get by 11pm, Today
₹291

₹262

order for
₹1200
4.3Rating star
Nixiyax Capsule
15 capsules
Get in 60 mins
₹445
₹484
8% off

₹401

order for
₹1200
Related ayurvedic ingredients
Saffron (Kesar)
Saffron (Kesar)
Chamomile
Chamomile
Ginkgo biloba
Ginkgo biloba
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities
<h3 class=titleMediumExtraBold>Want to know more</h3>

Want to know more

We provide you with authentic, trustworthy and relevant information
<h3 class=titleMediumExtraBold>Have issue with the content</h3>

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Swastik India Pvt Ltd
Address: DIAMOND PLAZA,391, DR. D.B.MARG, , MUMBAI, Maharashtra, India - 400004

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?
close sheet