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MD Pharmacology, MBBS
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Docetrust 20 Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Docetrust 20 Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.

Docetrust 20 Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Docetrust Injection

Benefits of Docetrust Injection

In Breast cancer

Docetrust 20 Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Docetrust 20 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Docetrust 20 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Docetrust 20 Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

In Cancer of head and neck

Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Docetrust 20 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but it has some bothersome side effects. Therefore, you should discuss the risks and benefits with your doctor.

Side effects of Docetrust Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Docetrust

  • Breathlessness
  • Constipation
  • Edema (swelling)
  • Infection
  • Loss of appetite
  • Muscle pain
  • Nail disorder
  • Pain
  • Weakness

How to use Docetrust Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Docetrust Injection works

Docetrust 20 Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Docetrust 20 Injection.
Pregnancy
CONSULT YOUR DOCTOR
Docetrust 20 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Docetrust 20 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Docetrust 20 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Docetrust 20 Injection is safe to use in patients with kidney disease. No dose adjustment of Docetrust 20 Injection is recommended.
Liver
CAUTION
Docetrust 20 Injection should be used with caution in patients with liver disease. Dose adjustment of Docetrust 20 Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Docetrust 20 Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.
  • Do not take Docetrust 20 Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
  • It may cause side effects such as swelling of hands, lips, and weight gain. To reduce these side effects your doctor may suggest some medication along with this medicine called Corticosteroids.
  • Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.

Fact Box

Chemical Class
Taxanes Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimicrotubule agents- Taxanes

Patient concerns

arrow
I want to know the symptoms of cancer as I am a smoker
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.
What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
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User feedback


FAQs

Q. Does Docetrust 20 Injection cause weight gain?

Yes, Docetrust 20 Injection may cause weight gain. It may occur due to fluid retention which may initially make your feet swell and then gradually it will spread to the whole body. Call your doctor immediately if you notice swelling of feet.

Q. How long do I have to take Docetrust 20 Injection?

You should continue to take Docetrust 20 Injection as long as your doctor advises you. The duration of treatment varies with the type of cancer you have and other factors like your response to treatment. You should usually receive your infusion once every 3 weeks.

Q. Can I drink alcohol while on Docetrust 20 Injection?

Docetrust 20 Injection injection contains alcohol because of which you may experience confusion, stumbling, becoming very sleepy, or feeling like you are drunk. This may impair your ability to drive or use machinery right after receiving it. Hence, you should avoid alcohol during Docetrust 20 Injection therapy, as it may affect you adversely.

Q. What is Docetrust 20 Injection used for?

Docetrust 20 Injection is commonly used for breast cancer, certain types of lung cancer, prostate, stomach, and head and neck cancers. It works by restricting cells from growing and multiplying.

Q. Is Docetrust 20 Injection available in pill form?

No, Docetrust 20 Injection injection comes as a liquid to be given intravenously (into a vein) by a doctor or nurse in a hospital or clinic. It is usually given over 1 hour once every 3 weeks.

Q. What blood tests are required before administration of Docetrust 20 Injection?

Your doctor will ask you to get blood tests every time you have a scheduled dose of Docetrust 20 Injection. You may be asked to have blood tests, such as hemogram and liver function tests, to ensure that you have enough blood cells and that your liver is functioning well enough to receive Docetrust 20 Injection. In case of white blood cells disturbances, you may experience associated fever or infections.

Q. Is hair loss caused by Docetrust 20 Injection irreversible?

Hair loss is a common side effect of Docetrust 20 Injection. Normal hair growth may resume after stopping Docetrust 20 Injection. However, in some cases there is permanent hair loss. Consult your doctor if you have any concerns regarding hair loss.

Q. Why is dexamethasone used with Docetrust 20 Injection?

Docetrust 20 Injection may cause fluid retention (swelling in the hands, feet, ankles and legs) as well as severe hypersensitivity reactions. To control such possibilities from occurring all patients are given corticosteroids (dexamethasone) for 3 days starting 1 day prior to Docetrust 20 Injection administration. In case of prostate cancer (metastatic castration-resistant), the recommended regimen is oral dexamethasone given at 12 hours, 3 hours, and 1 hour before the Docetrust 20 Injection infusion.

Q. What type of drug is Docetrust 20 Injection?

Docetrust 20 Injection belongs to the group of anti-cancer medicines called taxoids. It works by stopping the growth and spread of cancer cells.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 422-23.
  3. Docetaxel Injection. Unterach, Austria: EBEWE Pharma Ges.m.b.H. Nfg.KG; 1996 [revised Mar. 2012. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Docetaxel. [Updated 2019 Jun 30]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Panacea Biotec Pharma Ltd
Address: "Panacea Biotec Pharma Ltd B-1,Extn/A-27,Mohan Co-operative Industrial Estate Mathura Road, New Delhi-110044"
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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