Divalpro XR 250 Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store below 30°C

Introduction

Divalpro XR 250 Tablet is a medicine used to treat epilepsy. It helps prevent and control seizures (fits). It is also used in the prevention of migraines. Occasionally, it may also be used to treat bipolar disorder.

Divalpro XR 250 Tablet may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. You can take this medicine with or without food but take it at the same time each day to get the most benefit.

It usually takes a couple of weeks to work. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may trigger seizures and, if you stop, your condition may get worse. It should never be stopped suddenly.

This medicine's most common side effects include headache, blurred vision, nausea, vomiting, dizziness, tiredness, and unsteadiness. Most of these are not serious. Keep taking the medicine but talk to your doctor if these side effects bother you or do not go away. However, if you notice a skin rash or redness, tell your doctor straight away. Long-term treatment with this medicine can cause osteoporosis (reduced bone mass) and increase your risk of breaking a bone. Also, Divalpro XR 250 Tablet may rarely lead to suicidal thoughts and behaviors. If your mood becomes depressed, tell your doctor.

This medicine may not be suitable for everybody. Before using it, tell your doctor if you have ever had heart problems, kidney or liver disease, difficulty urinating, depression, or suicidal thoughts. Many other medicines can interfere with it and some should not be taken together so tell your doctor all the medicines you are taking to make sure it is safe. If you are pregnant, do not start or stop taking this medicine without asking your doctor. Drinking alcohol should be avoided as it can increase some of the side effects and can also increase your risk of seizures. You may need frequent blood tests to help your doctor make sure you are taking the right dose both before you start and while you are using it.

Uses of Divalpro Tablet PR

Benefits of Divalpro Tablet PR

In Epilepsy/Seizures

Divalpro XR 250 Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

In Bipolar disorder

Divalpro XR 250 Tablet works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

In Prevention of Migraine

It is not fully established how Divalpro XR 250 Tablet helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Divalpro Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Divalpro

  • Headache
  • Dizziness
  • Blurred vision
  • Weakness
  • Abdominal pain
  • Infection
  • Nausea
  • Vomiting
  • Sleepiness
  • Hair loss
  • Weight gain
  • Double vision
  • Diarrhea
  • Tremor
  • Weight loss
  • Flu-like symptoms

How to use Divalpro Tablet PR

Use it as advised by your doctor or check the label for directions before use. Divalpro XR 250 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Divalpro Tablet PR works

Divalpro XR 250 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
Divalpro XR 250 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Divalpro XR 250 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Divalpro XR 250 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Divalpro XR 250 Tablet may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Divalpro XR 250 Tablet is safe to use in patients with kidney disease. No dose adjustment of Divalpro XR 250 Tablet is recommended.
Liver
UNSAFE
Divalpro XR 250 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Divalpro Tablet PR?

If you miss a dose of Divalpro XR 250 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Divalpro XR 250 Tablet
₹7.64/Tablet PR
Dvs OD 250mg Tablet PR
Biologic Psychotropics India Pvt Ltd
₹7/Tablet PR
8% cheaper
₹7.25/Tablet PR
5% cheaper
₹7.75/Tablet PR
1% costlier
₹7.98/Tablet PR
4% costlier
Dilpra-OD 250 Tablet PR
Emcure Pharmaceuticals Ltd
₹8/Tablet PR
5% costlier

Quick Tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • It can be taken with or without food, but better to take it with food to avoid stomach upset.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • Your doctor may get regular blood tests done to monitor how the medication is affecting your body. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Chemical Class
Aliphatic Carboxylic acid Derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Sodium channel modulators (AED)

Interaction with Drugs

Taking Divalpro with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Eurolam, Tenzo, Indolam
SERIOUS
Brand(s): Equblam, Zepox, Raipox
SERIOUS
Brand(s): Risure, Boze, Clobazed
SERIOUS
Brand(s): Panik
SERIOUS

Patient Concerns

arrow
Treatment about bipolar disorder
Dr. Ravi Shankar M.
Ayurveda
Tab. Manasa Mitra Vataki 1-0-1 and Kalyanaka Ghritam 10 gram twice a day with luke warm wtar after food and Sarswatharishta 15 ml twice a day with equal quantity of water for 2 months
Suffering from bipolar disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
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FAQs

Q. What happens if I stop taking Divalpro XR 250 Tablet?

You should not stop taking Divalpro XR 250 Tablet without consulting your doctor. The dose of Divalpro XR 250 Tablet should be reduced gradually and eventually can be stopped under the supervision of a doctor or specialist. Suddenly stopping the medication may lead to a recurrence of symptoms, irritability, anxiety, dizziness, and tremors.

Q. Is Divalpro XR 250 Tablet a mood stabilizer?

Yes, Divalpro XR 250 Tablet can sometimes be used as a mood stabilizer. It is given to patients who experience rapid changes in their mood. It works by calming the hyperactivity of the brain during mood changes.

Q. Can Divalpro XR 250 Tablet cause weight gain?

Yes, Divalpro XR 250 Tablet may cause weight gain. The gain in weight could be due to an increase in hunger. Keep a check on your diet and exercise regularly to prevent any weight gain. If you have concerns related to weight gain, consult your doctor.

Q. Does Divalpro XR 250 Tablet make you sleepy?

Yes, Divalpro XR 250 Tablet may make you feel sleepy. Avoid driving or other work that requires mental focus until you know how it affects you.

Q. Does Divalpro XR 250 Tablet cause hair loss?

Yes, Divalpro XR 250 Tablet may cause hair loss. However, it is only for a short time and is usually dose-related. Please consult your doctor if the hair loss bothers you or persists for a longer duration.

Q. Can Divalpro XR 250 Tablet damage my liver?

Yes, Divalpro XR 250 Tablet can cause damage to the liver. The risk is more likely to occur during the first 6 months of starting the treatment with Divalpro XR 250 Tablet. Symptoms of liver damage may include nausea or vomiting, loss of appetite, stomach pain, dark-colored urine, facial swelling, yellowing of the skin, or whites of eyes. Therefore, it is important to have liver function tests done before starting the medicine and. Tests should be done periodically during the first 6 months of therapy, especially in those who are likely to be at risk and those with a prior history of liver disease.

Q. Can I take alcohol while I am taking Divalpro XR 250 Tablet?

Avoid alcohol consumption while you are on treatment with Divalpro XR 250 Tablet. Taking alcohol with this medicine may make you feel more drowsy, light-headed, or dizzy.

Q. What laboratory tests are recommended before taking Divalpro XR 250 Tablet?

The doctor may suggest blood tests before starting the treatment with Divalpro XR 250 Tablet. The tests may include blood cell count, including platelet count, bleeding time, and coagulation tests These tests are also advised to avoid any spontaneous bruising or bleeding. In addition to this, liver function tests are advised before therapy. It is recommended to periodically monitor liver function during the first 6 months of therapy, primarily in those who seem most at risk and those with a prior history of liver disease.

Q. What should be done if I start experiencing abdominal pain, nausea, and anorexia?

If you experience acute severe abdominal pain along with nausea and vomiting, it may be due to pancreatitis. Immediately consult your doctor in case you experience these symptoms. Your doctor may get your levels of serum amylase checked. In case the test shows positive results for pancreatitis, the medication should be stopped immediately.

Q. How to check for overdose of Divalpro XR 250 Tablet?

Overdose of Divalpro XR 250 Tablet may cause headaches, blurred eyesight due to pupils of the eyes becoming smaller, lack of reflexes, confusion and tiredness. You may also experience weak or “floppy” muscles, fits (seizures), loss of consciousness, behavioral changes and breathing difficulties such as fast breathing, shortness of breath, or chest pain. Immediate medical assistance is required in case of overdose.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Divalproex sodium. North Chicago: AbbVie Inc; 1983 [revised Feb. 2016]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  2. Divalproex sodium. North Chicago, IL: Abbott Laboratories; 2006. [Accessed 22 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of Origin: India

Expires on or after: July, 2022

A licensed vendor partner from your nearest location will deliver Divalpro XR 250 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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