Diprate-OD 250 Tablet ER

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)
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Introduction

Diprate-OD 250 Tablet ER is a medicine used to treat epilepsy. It helps prevent and control seizures (fits). It is also used in the prevention of migraines. Occasionally, it may also be used to treat bipolar disorder.

Diprate-OD 250 Tablet ER may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. You can take this medicine with or without food but take it at the same time each day to get the most benefit.

It usually takes a couple of weeks to work. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may trigger seizures and, if you stop, your condition may get worse. It should never be stopped suddenly.

This medicine's most common side effects include headache, blurred vision, nausea, vomiting, dizziness, tiredness, and unsteadiness. Most of these are not serious. Keep taking the medicine but talk to your doctor if these side effects bother you or do not go away. However, if you notice a skin rash or redness, tell your doctor straight away. Long-term treatment with this medicine can cause osteoporosis (reduced bone mass) and increase your risk of breaking a bone. Also, Diprate-OD 250 Tablet ER may rarely lead to suicidal thoughts and behaviors. If your mood becomes depressed, tell your doctor.

This medicine may not be suitable for everybody. Before using it, tell your doctor if you have ever had heart problems, kidney or liver disease, difficulty urinating, depression, or suicidal thoughts. Many other medicines can interfere with it and some should not be taken together so tell your doctor all the medicines you are taking to make sure it is safe. If you are pregnant, do not start or stop taking this medicine without asking your doctor. Drinking alcohol should be avoided as it can increase some of the side effects and can also increase your risk of seizures. You may need frequent blood tests to help your doctor make sure you are taking the right dose both before you start and while you are using it.

Uses of Diprate Tablet ER

Benefits of Diprate Tablet ER

In Epilepsy/Seizures

Diprate-OD 250 Tablet ER is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

In Bipolar disorder

Diprate-OD 250 Tablet ER works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

In Prevention of Migraine

It is not fully established how Diprate-OD 250 Tablet ER helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Diprate Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Diprate

  • Headache
  • Dizziness
  • Blurred vision
  • Weakness
  • Abdominal pain
  • Infection
  • Nausea
  • Vomiting
  • Sleepiness
  • Hair loss
  • Weight gain
  • Double vision
  • Diarrhea
  • Tremor
  • Weight loss
  • Flu-like symptoms

How to use Diprate Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diprate-OD 250 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.

How Diprate Tablet ER works

Diprate-OD 250 Tablet ER is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
Diprate-OD 250 Tablet ER may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Diprate-OD 250 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Diprate-OD 250 Tablet ER is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Diprate-OD 250 Tablet ER may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Diprate-OD 250 Tablet ER is safe to use in patients with kidney disease. No dose adjustment of Diprate-OD 250 Tablet ER is recommended.
Liver
UNSAFE
Diprate-OD 250 Tablet ER is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Diprate Tablet ER?

If you miss a dose of Diprate-OD 250 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Diprate-OD 250 Tablet ER
₹6.1/Tablet ER
Valp 250mg Tablet ER
Orchid Chemicals & Pharmaceuticals Ltd
₹6.17/Tablet ER
1% costlier
Divalgress ER 250 Tablet
La Renon Healthcare Pvt Ltd
₹6.3/Tablet ER
3% costlier
Dictate 250mg Tablet ER
Blue Eye Pharmaceuticals
₹6.3/Tablet ER
3% costlier
Divacon ER 250 Tablet
Mayflower India
₹6.6/Tablet ER
8% costlier
Divalid 250mg Tablet ER
Linux Laboratories
₹7.55/Tablet ER
24% costlier

Quick Tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • It can be taken with or without food, but better to take it with food to avoid stomach upset.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • Your doctor may get regular blood tests done to monitor how the medication is affecting your body. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Chemical Class
Aliphatic Carboxylic acid Derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Sodium channel modulators (AED)

Interaction with Drugs

Taking Diprate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Eurolam, Alwel, Tenzo
SERIOUS
Brand(s): Equblam, Raipox, Equiliser
SERIOUS
Brand(s): Risure, Boze, Clobazed
SERIOUS
Brand(s): Panik
SERIOUS

Patient Concerns

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Treatment about bipolar disorder
Dr. Ravi Shankar M.
Ayurveda
Tab. Manasa Mitra Vataki 1-0-1 and Kalyanaka Ghritam 10 gram twice a day with luke warm wtar after food and Sarswatharishta 15 ml twice a day with equal quantity of water for 2 months
Suffering from bipolar disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
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FAQs

Q. What happens if I stop taking Diprate-OD 250 Tablet ER?

You should not stop taking Diprate-OD 250 Tablet ER without consulting your doctor. The dose of Diprate-OD 250 Tablet ER should be reduced gradually and eventually can be stopped under the supervision of a doctor or specialist. Suddenly stopping the medication may lead to a recurrence of symptoms, irritability, anxiety, dizziness, and tremors.

Q. Is Diprate-OD 250 Tablet ER a mood stabilizer?

Yes, Diprate-OD 250 Tablet ER can sometimes be used as a mood stabilizer. It is given to patients who experience rapid changes in their mood. It works by calming the hyperactivity of the brain during mood changes.

Q. Can Diprate-OD 250 Tablet ER cause weight gain?

Yes, Diprate-OD 250 Tablet ER may cause weight gain. The gain in weight could be due to an increase in hunger. Keep a check on your diet and exercise regularly to prevent any weight gain. If you have concerns related to weight gain, consult your doctor.

Q. Does Diprate-OD 250 Tablet ER make you sleepy?

Yes, Diprate-OD 250 Tablet ER may make you feel sleepy. Avoid driving or other work that requires mental focus until you know how it affects you.

Q. Does Diprate-OD 250 Tablet ER cause hair loss?

Yes, Diprate-OD 250 Tablet ER may cause hair loss. However, it is only for a short time and is usually dose-related. Please consult your doctor if the hair loss bothers you or persists for a longer duration.

Q. Can Diprate-OD 250 Tablet ER damage my liver?

Yes, Diprate-OD 250 Tablet ER can cause damage to the liver. The risk is more likely to occur during the first 6 months of starting the treatment with Diprate-OD 250 Tablet ER. Symptoms of liver damage may include nausea or vomiting, loss of appetite, stomach pain, dark-colored urine, facial swelling, yellowing of the skin, or whites of eyes. Therefore, it is important to have liver function tests done before starting the medicine and. Tests should be done periodically during the first 6 months of therapy, especially in those who are likely to be at risk and those with a prior history of liver disease.

Q. Can I take alcohol while I am taking Diprate-OD 250 Tablet ER?

Avoid alcohol consumption while you are on treatment with Diprate-OD 250 Tablet ER. Taking alcohol with this medicine may make you feel more drowsy, light-headed, or dizzy.

Q. What laboratory tests are recommended before taking Diprate-OD 250 Tablet ER?

The doctor may suggest blood tests before starting the treatment with Diprate-OD 250 Tablet ER. The tests may include blood cell count, including platelet count, bleeding time, and coagulation tests These tests are also advised to avoid any spontaneous bruising or bleeding. In addition to this, liver function tests are advised before therapy. It is recommended to periodically monitor liver function during the first 6 months of therapy, primarily in those who seem most at risk and those with a prior history of liver disease.

Q. What should be done if I start experiencing abdominal pain, nausea, and anorexia?

If you experience acute severe abdominal pain along with nausea and vomiting, it may be due to pancreatitis. Immediately consult your doctor in case you experience these symptoms. Your doctor may get your levels of serum amylase checked. In case the test shows positive results for pancreatitis, the medication should be stopped immediately.

Q. How to check for overdose of Diprate-OD 250 Tablet ER?

Overdose of Diprate-OD 250 Tablet ER may cause headaches, blurred eyesight due to pupils of the eyes becoming smaller, lack of reflexes, confusion and tiredness. You may also experience weak or “floppy” muscles, fits (seizures), loss of consciousness, behavioral changes and breathing difficulties such as fast breathing, shortness of breath, or chest pain. Immediate medical assistance is required in case of overdose.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Divalproex sodium. North Chicago: AbbVie Inc; 1983 [revised Feb. 2016]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  2. Divalproex sodium. North Chicago, IL: Abbott Laboratories; 2006. [Accessed 22 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Solvate Laboratories Pvt.Ltd., C-57, IIIrd Floor, Vikas Marg, Preet Vihar, Delhi-110092
Country of Origin: India

MRP
61.04
Inclusive of all taxes
10 tablet er in 1 strip
SOLD OUT

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