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MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
15 Jul 2019 | 05:11 PM (IST)
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Difit IT 100 Capsule


Overview

Uses of Difit IT Capsule

Difit IT Capsule side effects

Common
  • Nausea
  • Diarrhea
  • Stomach pain
  • Skin rash
  • Increased liver enzymes

How to use Difit IT Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Difit IT 100 Capsule is to be taken with food.
If you are taking oral solution, it should be taken one hour before any food or drink.

How Difit IT Capsule works

Difit IT 100 Capsule is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your skin infection.

Difit IT Capsule related warnings

Alcohol
SAFE
It is generally safe to consume alcohol with Difit IT 100 Capsule.
Pregnancy
WEIGH RISKS VS BENEFITS
Difit IT 100 Capsule may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Difit IT 100 Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
Difit IT 100 Capsule can sometimes cause dizziness, blurred/double vision or hearing loss. This may affect your ability to drive.
Kidney
There is limited information available on the use of Difit IT 100 Capsule in patients with kidney disease. Please consult your doctor.
Liver
There is limited information available on the use of Difit IT 100 Capsule in patients with liver disease. Please consult your doctor.
Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.

What if you miss a dose of Difit IT Capsule?

If you miss a dose of Difit IT 100 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Difit IT 100 Capsule
₹12.05/Capsule
Itrasys 100 Capsule
Systopic Laboratories Pvt Ltd
₹9/Capsule
save 25%
₹13.71/Capsule
14% costlier
Fungikem 100 Capsule
Alkem Laboratories Ltd
₹16.5/Capsule
37% costlier
Canditral 100 Capsule
Glenmark Pharmaceuticals Ltd
₹19.7/Capsule
63% costlier
Syntran Capsule
Glenmark Pharmaceuticals Ltd
₹19.7/Capsule
63% costlier

Expert Advice

  • Difit IT 100 Capsule helps treat fungal infections of mouth, skin, vagina or any other parts of the body.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Take it with food, preferably at the same time everyday.
  • Use a reliable method of contraception to prevent pregnancy while taking this medicine.
  • Do not take indigestion remedies (antacids) within two hours of taking Difit IT 100 Capsule.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Inform your doctor if you develop  allergic reactions, nerve pain, or hearing loss.

Interaction with Drugs

Taking Difit IT with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Quitsun, Qutec
LIFE-THREATENING
Brand(s): Zipris
LIFE-THREATENING
Brand(s): Norma, Cizonil
LIFE-THREATENING
Brand(s): Oladac
LIFE-THREATENING
Brand(s): Antep
LIFE-THREATENING
Brand(s): R Zep
LIFE-THREATENING
Brand(s): Loxaris
LIFE-THREATENING
Brand(s): Stozen
LIFE-THREATENING
Brand(s): Suclosz, Vizopin
LIFE-THREATENING
Brand(s): Arifril
LIFE-THREATENING

Patient Concerns

Questions Related to Difit IT

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My nail cover is not regenerating as it should be. This thing happened some time back when my Hb was down to 8. But noe Hb is normal. It is 13.
Dr. Atul Jain
Skin Specialist
I think you are having fungal infections, you should visit skin specialist for proper examination and treatment
I have fungal infections on my legs, it itchsI am using fluka 150 mg but not getting positive resultsWith Tenovat M skin cream
Dr. Preeti Chhabra
Skin Specialist
Apply Fungase ointment, Nimba Tail and Karanj tail
arrow
Do you have any questions related to Difit IT 100 Capsule?

FAQs

Q. What is Difit IT used for?

Difit IT is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection in groin and buttocks and infection of feet. This medicine also treats persistent infection of finger nails and toe nails, persistent candida (yeast) infections of vagina, candida (yeast) infections of the mouth or throat in patients with lower resistance to disease, cryptococcal infection, and infections caused by histoplasma, aspergillus and blastomyces.

Q. For how long do I need to take Difit IT?

The dose and length of treatment depends on the type and site of infection and your response to the treatment. For example, if you are taking Difit IT for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days, while for candidal infection of vagina, the dose may span from 1 day to 3 days depending on the dosage advised by the doctor.

Q. What should I do if I skip a dose of Difit IT?

Take the missed dose as soon as you remember it. However, if it is time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the forgotten dose.

Q. I am taking Difit IT for nail infection but there does not seem to be any improvement. Can I stop taking it?

No, you should not stop taking Difit IT. Complete the entire course because if you do not complete the course, your infection will not be completely cured of the fungal infection. Nail lesions usually take about 6-9 months to disappear after treatment because after the medicine eliminates the fungus, the new nail takes several months to grow. Do not worry if you see any improvement during the treatment. The medicine will remain in your nails for several months and keep doing its job.

Q. Why has my doctor asked me to get blood tests done?

Your doctor is probably trying to monitor your liver’s functioning. Difit IT may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine or abdominal pain while taking Difit IT, you should tell your doctor immediately.

Q. Can I take antacid and Difit IT together?

Difit IT can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn or indigestion neutralize the acid produced by the stomach. Therefore, take any such medicine for about 2 hours after taking Difit IT. If you are taking antacids (medicines that stop the production of stomach acid), you should take Difit IT capsules with a drink of cola.

Q. What is drug resistance? Is it possible to develop resistance to Difit IT?

Sometimes it happens that the fungi gets modified in your body and the medicine no longer works. This is called drug resistance. Resistance to Difit IT has been reported with some candida species (krusei, glabrata and tropicalis). Difit IT should not be used for infection caused due to these species.. Take the complete course of Difit IT to avoid drug resistance.

Q. I am on alprazolam for quite some time. Is it okay if I start Difit IT now?

Yes, you can take both alprazolam and Difit IT together, but keep a watch on the side effects of alprazolam. If side effects appear after taking Difit IT, talk to your doctor who will modify the dose of alprazolam.

Q. My doctor prescribed Difit IT to me but not to my friend who had similar fungal infection because she was on dofetilide. Why is it so?

Your doctor did not prescribe Difit IT to your friend because Difit IT interferes with working of dofetilide. This interference can cause disturbed electrical activity of heart, which can be detrimental for the patient.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1576-79.
  2. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 839-40.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 749-51.
  4. Itraconazole. Camberley, Surrey: Sandoz Limited; 2009 [revised 31 Aug. 2018]. [Accessed 29 Mar. 2019] (online) Available from:External Link
  5. Itraconazole. Turnhout, Belgium: Sanico N.V.; 1992 [revised Apr. 2010]. [Accessed 29 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
DIVINE LIFE CARE PVT LTD, 220, MAHAGUJARAT IND. ESTATE AT, PO : MORAIYA, TA : SANAND DIST : AHMEDABAD
A licensed pharmacy from your nearest location will deliver Difit IT 100 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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