Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Sakshi Jain

MS, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

19 Jan 2026 | 09:19 PM (IST)

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Home>Dezil-Plus>dezil-plus 10 tablet

Dezil-Plus 10 Tablet

Prescription Required

Marketer

Ryon Pharma

SALT COMPOSITION

Donepezil (5mg) + Memantine (10mg)

Storage

Store below 30°C

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

Dezil-Plus 10 Tablet is a prescription medicine used to treat Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's by improving memory and thinking. It also increases the levels of a chemical messenger involved in the transmission of nerve signals.

Dezil-Plus 10 Tablet can be taken with or without food, but you may take it with food to avoid a stomach upset. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. Do not skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better and do not stop taking it suddenly.

Some common side effects of this medicine include nausea, vomiting, loss of appetite, fatigue, and headache. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Drink plenty of fluids to keep yourself hydrated while taking this medicine as this medicine may cause diarrhea.

Before using this medicine, you should tell your doctor if you have ever had heart problems, stomach ulcers, epilepsy or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Dezil-Plus Tablet

Alzheimer's disease

Side effects of Dezil-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dezil-Plus

Weight loss
Drug allergy
Balance disorder (loss of balance)
High blood pressure
Breathlessness
Diarrhea
Nausea
Muscle cramp
Dizziness
Headache
Insomnia (difficulty in sleeping)

How to use Dezil-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dezil-Plus 10 Tablet may be taken with or without food.

How Dezil-Plus Tablet works

Dezil-Plus 10 Tablet is a combination of two medicines: Donepezil and Memantine which treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor while Memantine is an NMDA inhibitor. Together, they balance the levels of chemical messengers in the brain and help in the transmission of nerve signals.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Dezil-Plus 10 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Dezil-Plus 10 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Dezil-Plus 10 Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Dezil-Plus 10 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Dezil-Plus 10 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Dezil-Plus 10 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Dezil-Plus 10 Tablet should not used in severe hepatic impairment.

What if you forget to take Dezil-Plus Tablet?

If you miss a dose of Dezil-Plus 10 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Dezil-Plus 10 Tablet

₹12.7/Tablet

Donamem 10 Tablet

Sun Pharmaceutical Industries Ltd

₹23.4/tablet

84% costlier

Alzil-M 10 Tablet

Intas Pharmaceuticals Ltd

₹29/tablet

128% costlier

Aricep-M Forte Tablet

Eisai Pharmaceuticals India Pvt Ltd

₹19.2/tablet

51% costlier

Larentine D 5mg/10mg Tablet

La Renon Healthcare Pvt Ltd

₹21.3/tablet

68% costlier

Donamind M 5mg/10mg Tablet

Icon Life Sciences

₹22/tablet

73% costlier

View all substitutes

Quick tips

Dezil-Plus 10 Tablet is used for the symptomatic treatment of alzheimer's disease. It does not cure alzheimer's, but may help with brain function and doing daily activities.
Monitor your body weight regularly as both Dezil-Plus 10 Tablet and alzheimer's disease can cause weight loss.
Don't drive or do anything that requires mental focus until you know how it affects you.
Inform your doctor if you have a history of seizures as it may raise the chances of seizure if you had them in the past.
It may cause stomach ulcers, specially if you are also taking medications for inflammation or pain. Talk to your doctor if you vomit blood or have black colored stools.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

Is Dytor plus Ls" is same as "Dytor plus 10" ?"

Dr. Pushkar Mani

Physician

its same but dosage is different , u cant switch

I had recently undergone left humerus plating surgery and i was told to take setfrac plus tablet The problem is setfrac plus tablet is not available in my town so can u please sugeat the substitute tablet to setfrac plus?????

Dr. Rohit Chakor

Orthopaedics

You see the content of the tablet and ask for it

I took almost a month before Azathral 500 for throat infection. While taking it on third day I suffered from diarrhea. Even now I am having a tendency to evacuate every now and then. I used to go to bathroom thrice or four times regularly. Before taking the medicine I was two times goer to bathroom. Please suggest me What to do.

Dr. Tapas Kumbhkar

Internal Medicine

Tab sporlac plus 1BD FOR 10 DAYS

What are the instructions for the storage and disposal of Dezil-Plus 10 Tablet?

Keep this medicine in the packet or container it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

What are the contraindications to the use of Dezil-Plus 10 Tablet?

Dezil-Plus 10 Tablet is contraindicated in patients who are allergic to Memantine, Donepezil or any of its constituents. Also, inform your doctor about all of patients medical history before using this medicine.

What should I inform my doctor before using Dezil-Plus 10 Tablet?

Before taking Dezil-Plus 10 Tablet, tell the doctor about all of patient's past and present medical conditions, including: problem in heart, lung, liver, kidney or bladder, seizures, stomach ulcers or any scheduled medical procedures. Also, inform your doctor about all the medicines patient takes.

What if the patient takes more of Dezil-Plus 10 Tablet than recommended?

If the patient overdose on Dezil-Plus 10 Tablet, go to nearest medical emergency department or call your doctor immediately.

Can the use of Dezil-Plus 10 Tablet cause diarrhea?

Yes, the use of Dezil-Plus 10 Tablet can cause diarrhea. In case, the patient experience diarrhea, talk to the doctor. Do not take any other medicines without speaking to a doctor.

What should I inform my doctor before using Dezil-Plus 10 Tablet?

What if the patient takes more of Dezil-Plus 10 Tablet than recommended?

If the patient overdose on Dezil-Plus 10 Tablet, go to nearest medical emergency department or call your doctor immediately.

Can the use of Dezil-Plus 10 Tablet cause diarrhea?

Yes, the use of Dezil-Plus 10 Tablet can cause diarrhea. In case, the patient experience diarrhea, talk to the doctor. Do not take any other medicines without speaking to a doctor.

What are the instructions for the storage and disposal of Dezil-Plus 10 Tablet?

What are the contraindications to the use of Dezil-Plus 10 Tablet?

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.