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Desferal 500mg Injection

Deferoxamine (500mg)

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Desferal 500mg Injection is a medicine used in the treatment of chronic iron overload caused due to frequent blood transfusion. It helps in removing the excess iron from the body and reduces the risk of it causing organ damage.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 30 Oct 2026 | 12:41 PM (IST)

₹283 MRP ₹297.125% off

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Deferoxamine (500mg)

Marketer

Novartis India Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Desferal 500mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine.

Using of Desferal 500mg Injection may cause few side effects such as flushing (a sense of warmth in the face, ears, neck and trunk), rash, decreased blood pressure and abdominal pain. If the side effects persist or worsen, inform your doctor.

Uses of Desferal Injection

Benefits of Desferal Injection

Iron overload
Iron overload is a condition where iron accumulates in the body due to repeated transfusions or certain medical conditions. If left unmanaged, it can damage the liver, heart, and other organs. Desferal 500mg Injection helps reduce iron levels in the body, lowering the risk of long-term complications and supporting organ health.

Transfusion dependent thalassemia
Transfusion-dependent thalassemia is a blood disorder where the body cannot make enough healthy red blood cells, leading to severe anemia. To manage this, patients require frequent blood transfusions, which gradually lead to a buildup of excess iron in the body. Desferal 500mg Injection helps by binding to this excess iron and removing it through urine and stool. This supports safe long-term transfusion therapy by preventing iron from harming vital organs.

Side effects of Desferal Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Desferal

Injection site reactions (pain, swelling, redness)
Fungal infection
Cardiovascular disorders
Liver disorder
Musculoskeletal (bone, muscle or joint) pain
Urogenital disorders
Nervous system disorder
Respiratory disorder
Eye disorder
Hearing disorder
Hypersensitivity
Gastrointestinal disturbance
Hematological disorder

How to use Desferal Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Desferal Injection works

Desferal 500mg Injection traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

Quick tips

Desferal 500mg Injection is used to reduce excess iron from the body.
Desferal 500mg Injection may cause your urine to turn a red/brown color. This is the iron being removed from your body and is nothing for you to worry about as it is quite harmless.
If you are taking any antacid, take them 2 hours before or after Desferal 500mg Injection.
Desferal 500mg Injection may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Desferal 500mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Desferal 500mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Desferal 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CAUTION

Desferal 500mg Injection may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
If you experience dizziness or other central nervous disturbances, or impairment of vision with the use of Desferal 500mg Injection then you should refrain from driving a vehicle.

Kidney

UNSAFE

Desferal 500mg Injection is unsafe to use in patients with kidney disease and should be avoided.
Use of Desferal 500mg Injection is not recommended in patients with severe kidney disease.

Liver

CAUTION

Desferal 500mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Desferal with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Prochlorperazine (Oral Route)

If concurrent use is essential, please consult your doctor. Prochlorperazine may increase the side effects of Deferoxamine.

Moderate

Prochlorperazine (Injection Route)

If concurrent use is essential, please consult your doctor. Prochlorperazine may increase the side effects of Deferoxamine.

Frequently asked questions

How does Desferal 500mg Injection help treat iron overload?

Desferal 500mg Injection binds to excess iron in the body and helps remove it through urine and stool. This reduces iron buildup and helps lower the risk of damage to organs such as the heart and liver.

Why may my urine turn reddish-brown after taking Desferal 500mg Injection?

Desferal 500mg Injection removes excess iron from the body, and this may make your urine appear reddish-brown. Inform your doctor if you notice any unusual changes or other symptoms.

Does Desferal 500mg Injection require regular monitoring during treatment?

Yes. Your doctor may recommend regular blood tests to check iron levels and kidney function, along with hearing and eye tests, particularly during long-term treatment.

Can Desferal 500mg Injection affect hearing or vision?

Yes. In some cases, Desferal 500mg Injection may cause hearing problems, ringing in the ears, blurred vision, or other changes in eyesight. Inform your doctor promptly if you notice any of these symptoms.

Can Desferal 500mg Injection affect kidney function?

Yes. Desferal 500mg Injection may affect kidney function and is not suitable for people with severe kidney disease or very low urine output. Inform your doctor about any kidney problems before treatment.

What should I do if I develop a rash or difficulty breathing after receiving Desferal 500mg Injection?

Seek immediate medical attention if you develop difficulty breathing, swelling of the face or throat, or a severe allergic reaction. Rapid administration into a vein can also cause a sudden drop in blood pressure.

Can I stop receiving Desferal 500mg Injection once my iron levels improve?

Do not stop or change treatment on your own. Your doctor will monitor your iron levels and decide whether your dose or treatment schedule needs to be adjusted.

Fact Box

Chemical Class

Acetohydroxamic acids

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Iron Chelators

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

References

Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365-66.
Deferoxamine. Stein, Switzerland: Novartis Pharma Stein AG; 2011. [Accessed 6 Apr. 2019] (online) Available from:

User feedback

Patients taking Desferal 500mg Injection

Once A Day

65%

Once A Month

10%

Once A Week

Alternate Day

Twice A Day

Four Times A Day

Thrice A Day

What are you using Desferal Injection for?

Transfusion dependent thalassemia

58%

Iron overload

33%

Others

How much was the improvement?

Average

56%

Excellent

28%

Poor

17%

What were the side-effects while using Desferal 500mg Injection?

Abdominal pain

33%

No Side Effect

33%

Flushing (sense of warmth in the face, ears, neck and trunk)

33%

How do you take Desferal Injection?

With food

67%

With or without food

33%

Please rate Desferal 500mg Injection on price

Expensive

67%

Not Expensive

17%

Average

17%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Blood Related

Chelating Agents

Desferal 500mg Injection

Desferal 500mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Desferal Injection

Benefits of Desferal Injection

Side effects of Desferal Injection

How to use Desferal Injection

How Desferal Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Prochlorperazine (Oral Route)

Prochlorperazine (Injection Route)

Frequently asked questions

How does Desferal 500mg Injection help treat iron overload?

Why may my urine turn reddish-brown after taking Desferal 500mg Injection?

Does Desferal 500mg Injection require regular monitoring during treatment?

Can Desferal 500mg Injection affect hearing or vision?

Can Desferal 500mg Injection affect kidney function?

What should I do if I develop a rash or difficulty breathing after receiving Desferal 500mg Injection?

Can I stop receiving Desferal 500mg Injection once my iron levels improve?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

References

User feedback

Patients taking Desferal 500mg Injection

What are you using Desferal Injection for?

How much was the improvement?

What were the side-effects while using Desferal 500mg Injection?

How do you take Desferal Injection?

Please rate Desferal 500mg Injection on price

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Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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