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Denoci 60 Injection

Denosumab (60mg/ml)

Genuine

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Prescription

required

Cold stored

Stored between 2-8°C

Denoci 60 Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Apr 2026 | 12:26 PM (IST)

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1 ml Injection

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General Information

Contains

Denosumab (60mg/ml)

Marketer

Cipla Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Denoci 60 Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine.

Some common side effects of this medicine include headache, pain in extremity, musculoskeletal pain, nerve pain, constipation, and rash. Talk to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.

Uses of Denoci Injection

Osteoporosis

Benefits of Denoci Injection

Osteoporosis
Osteoporosis is a condition where bones become weak and brittle, making them more prone to fractures even with minor falls or injuries. Denoci 60 Injection helps slow down bone breakdown and increases bone density, reducing the risk of fractures in the spine, hip, and other bones. This supports stronger, healthier bones and improves overall bone strength.

Side effects of Denoci Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Denoci

Rash
Musculoskeletal (bone, muscle or joint) pain
Eczema
Upper respiratory tract infection
Sciatica
Pain in extremities
Back pain
Joint pain
Urinary tract infection
Constipation
Abdominal discomfort
Hair loss
Hypercholesterolemia (high cholesterol)
Cystitis
Nerve pain
Headache

How to use Denoci Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Denoci Injection works

Denoci 60 Injection is a monoclonal antibody. It binds to a protein that causes bone loss, thereby strengthening the bone and minimizing the risk of fractures.

All substitutes for Denoci 60 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Denoci 60 Injection is a medication used to treat thinning of the bones (called osteoporosis).
Take calcium and vitamin D to help build your bones when taking Denoci 60 Injection.
Do not take if you are pregnant or plan to become pregnant.
May cause a rare problem of the jaw (osteonecrosis), mostly seen after a dental procedure. Tell your doctor if you develop sudden jaw pain.
Denoci 60 Injection may also increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
Tell your doctor if you develop a rash while taking Denoci 60 Injection.
Denoci 60 Injection is a medication used to treat thinning of the bones (called osteoporosis).
Take calcium and vitamin D to help build your bones when taking Denoci 60 Injection.
Do not take if you are pregnant or plan to become pregnant.
May cause a rare problem of the jaw (osteonecrosis), mostly seen after a dental procedure. Tell your doctor if you develop sudden jaw pain.
Denoci 60 Injection may also increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
Tell your doctor if you develop a rash while taking Denoci 60 Injection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Denoci 60 Injection. Please consult your doctor.

Pregnancy

UNSAFE

Denoci 60 Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CAUTION

Denoci 60 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Denoci 60 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Denoci 60 Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

SAFE IF PRESCRIBED

Denoci 60 Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Denoci with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Cinacalcet (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Denosumab may increase the metabolism of Cinacalcet.

Frequently asked questions

How long can you stay on Denoci 60 Injection?

There is no optimal duration of treatment of osteoporosis with Denoci 60 Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denoci 60 Injection. Depending on this, the duration of taking Denoci 60 Injection is decided.

Does Denoci 60 Injection cause hair loss?

Yes, hair loss is a common side effect of Denoci 60 Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.

Is Denoci 60 Injection a chemotherapy drug?

Denoci 60 Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denoci 60 Injection makes the bones stronger and less likely to break.

How is Denoci 60 Injection given and how often?

Denoci 60 Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denoci 60 Injection.

Can Denoci 60 Injection be taken during pregnancy?

No, pregnant women should not take Denoci 60 Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Denoci 60 Injection if you can become pregnant.

How should Denoci 60 Injection be stored?

Denoci 60 Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.

Does Denoci 60 Injection cause osteonecrosis of the jaw?

Osteonecrosis is a rare side effect of Denoci 60 Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Denoci 60 Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

How long can you stay on Denoci 60 Injection?

Does Denoci 60 Injection cause hair loss?

Yes, hair loss is a common side effect of Denoci 60 Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.

Is Denoci 60 Injection a chemotherapy drug?

How is Denoci 60 Injection given and how often?

Can Denoci 60 Injection be taken during pregnancy?

How should Denoci 60 Injection be stored?

Does Denoci 60 Injection cause osteonecrosis of the jaw?

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Bone Resorption Inhibitors- Monoclonal Antibodies

Related lab tests

Calcium

References

Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1299.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 370.
Denosumab. Milton Road, Cambridge: Amgen Ltd.; 2010 [revised Jun. 2018]. [Accessed 02 Apr. 2019] (online) Available from:
Denosumab [Prescribing Information]. Thousand Oaks, California: Amgen Manufacturing Limited; 2013. [Accessed 20 Feb. 2024] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Denoci 60 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Denoci 60 Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Denoci Injection

Benefits of Denoci Injection

Side effects of Denoci Injection

How to use Denoci Injection

How Denoci Injection works

All substitutes for Denoci 60 Injection

Denu Injection

Denoci-OP Injection

Odensomab Injection

Densurank 60mg Injection

Denbri Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cinacalcet (Oral Route)

Frequently asked questions

How long can you stay on Denoci 60 Injection?

Does Denoci 60 Injection cause hair loss?

Is Denoci 60 Injection a chemotherapy drug?

How is Denoci 60 Injection given and how often?

Can Denoci 60 Injection be taken during pregnancy?

How should Denoci 60 Injection be stored?

Does Denoci 60 Injection cause osteonecrosis of the jaw?

How long can you stay on Denoci 60 Injection?

Does Denoci 60 Injection cause hair loss?

Is Denoci 60 Injection a chemotherapy drug?

How is Denoci 60 Injection given and how often?

Can Denoci 60 Injection be taken during pregnancy?

How should Denoci 60 Injection be stored?

Does Denoci 60 Injection cause osteonecrosis of the jaw?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Calcium

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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