Decapeptyl Depot Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of uterus grows excessively and causes symptoms like pain, heavy or irregular periods), and central precocious puberty (very early puberty).

Decapeptyl Depot Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Hot flashes, weakness, increased sweating, fatigue, back pain, and erectile dysfunction are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Decapeptyl Injection

Benefits of Decapeptyl Injection

In Prostate cancer

Decapeptyl Depot Injection is used in prostate cancer to help lower hormone levels that fuel cancer growth. It slows disease progression and helps relieve related symptoms, supporting better management of advanced cases.

In Endometriosis

Decapeptyl Depot Injection is used in endometriosis to reduce pain and discomfort by controlling hormone levels that contribute to abnormal tissue growth. It helps relieve symptoms like pelvic pain and improves daily comfort.

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Side effects of Decapeptyl Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Decapeptyl

Weakness
Increased sweating
Back pain
Paresthesia (tingling or pricking sensation)
Hot flashes
Erectile dysfunction

How to use Decapeptyl Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Decapeptyl Injection works

Decapeptyl Depot Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Decapeptyl Depot Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Decapeptyl Depot Injection. Please consult your doctor.

Pregnancy

UNSAFE

Decapeptyl Depot Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Decapeptyl Depot Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Decapeptyl Depot Injection may cause side effects which could affect your ability to drive.
You may feel dizzy, tired or have problems with your eyesight such as blurred vision. This may affect your driving ability.

Kidney

CAUTION

Decapeptyl Depot Injection should be used with caution in patients with kidney disease. Dose adjustment of Decapeptyl Depot Injection may be needed. Please consult your doctor.

Liver

CAUTION

Decapeptyl Depot Injection should be used with caution in patients with liver disease. Dose adjustment of Decapeptyl Depot Injection may be needed. Please consult your doctor.

What if you forget to take Decapeptyl Injection?

If you miss a dose of Decapeptyl Depot Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Decapeptyl Depot Injection

₹6548/Injection

Gonapeptyl 3.75mg Injection

Ferring Pharmaceuticals

₹1014.5/injection

86% cheaper

Bdrelin 3.75mg Injection

BDR Pharmaceuticals Internationals Pvt

₹7200/injection

1% cheaper

Quick tips

Decapeptyl Depot Injection helps in the treatment of locally advanced or metastatic prostate cancer.
It is given as an injection either under the skin or into a muscle.
It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
It may also be used to treat endometriosis and precocious puberty (premature puberty).

Fact Box

Chemical Class

Polypeptides

Habit Forming

Therapeutic Class

HORMONES

Action Class

Gonadotropin-releasing hormone (GnRH) Agonists

Interaction with drugs

Taking Decapeptyl with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Domperidone (Oral Route) Life-threatening

Do not consume Triptorelin with Domperidone. Concomitant use may affect heart rhythm and can be fatal.

Artemether (Oral Route) Severe

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p... More

Amiodarone (Oral Route) Severe

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p... More

Amiodarone (Injection Route) Severe

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p... More

Artemether (Injection Route) Severe

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p... More

View all drug interactions

Patient concerns

2 times had miscarriage hypothyroidism positive 2cm endometriosis cyst with pcod and rest all test is normal recently gone through 3 month decapeptyl ink treatment but cyst is as usual as per cyst is so small kindly suggest best advice decapeptyl treatment start in nov. 2016 and. Took 3 injection of decapeptyl monthly and now period come and i re did ultrasound but no improvement in endometriosis cyst All test like Apla , Torch , chromosomal study are normal

Dr. Asmita Kaundal

Obstetrics and Gynaecology

endometrial cyst is small do not worry abt it. try to concieve. keep taking medicine for thyroid. and tab folic acid 5 mg once daily.

Her bone age is 10 yrs 9 months . Can I give decapeptyl injection to stop puberty . She is very short Worried about bone density

Dr. Gopal Bansilal Samdani

Paediatrics

There are many underlying causes of patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

May not be prostate cancer, it is only begnin enlargement of prostate.

User feedback

Patients taking Decapeptyl Depot Injection

Once A Month

75%

Once A Week

Once A Day

Twice A Month

What are you using Decapeptyl Injection for?

Others

80%

Prostate canc*

20%

*Prostate cancer

How much was the improvement?

Average

56%

Excellent

28%

Poor

17%

What were the side-effects while using Decapeptyl Depot Injection?

No Side Effec*

30%

Breast enlarg*

10%

Sexual dysfun*

10%

Paresthesia (*

10%

Increased swe*

10%

*No Side Effect, Breast enlargement, Sexual dysfunction, Paresthesia (tingling or pricking sensation), Increased sweating

How do you take Decapeptyl Injection?

With food

67%

With or witho*

33%

*With or without food

Please rate Decapeptyl Depot Injection on price

Expensive

100%

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

Related ayurvedic ingredients

Garlic

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1410-11.
Triptorelin pamoate. Slough, Berkshire: Ipsen Ltd.; 2010 [revised 17 Dec. 2016]. [Accessed 23 Jan. 2019] (online) Avaialble from:
Triptorelin pamoate. Martigny, Switzerland: Debio RP; 2000 [Accessed Jul. 2014]. [Accessed 27 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from: