Dacazee 200 Injection

Dacarbazine (200mg)

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NPPA Regulated

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Cold stored

Stored between 2-8°C

Dacazee 200 Injection is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 Apr 2026 | 04:20 PM (IST)

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General Information

Contains

Dacarbazine (200mg)

Marketer

Zee Laboratories

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Dacazee 200 Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, and decreased white blood cell count, and injection site pain,. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Dacazee Injection

Benefits of Dacazee Injection

Malignant melanoma
Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Dacazee 200 Injection sticks to the genetic code, called DNA,of the cancer cells and kills them . It also prevents their growth and further spread. This helps to treat the cancer.

Side effects of Dacazee Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dacazee

Nausea
Vomiting
Injection site pain
Decreased white blood cell count
Loss of appetite

How to use Dacazee Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dacazee Injection works

Dacazee 200 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

All substitutes for Dacazee 200 Injection

For information purposes only. Consult a doctor before taking any medicine.

Dti Korea 200mg Injection

by Ferring Pharmaceuticals

₹83.44/injection

79% cheaper

Darzine 200 Injection

by Samarth Life Sciences Pvt Ltd

₹60.96/injection

85% cheaper

Quick tips

Dacazee 200 Injection is given as an injection into veins under the supervision of a doctor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Dacazee 200 Injection

Pregnancy

CONSULT YOUR DOCTOR

Dacazee 200 Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Dacazee 200 Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Dacazee 200 Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Dacazee 200 Injection may influence the ability to drive because of its central nervous system side effects.

Kidney

CAUTION

Dacazee 200 Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Dacazee 200 Injection in patients with liver disease.

Interaction with drugs

Taking Dacazee with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not use Dacarbazine with Cholera Vaccine (Inactivated). If Dacarbazine is essential, ensure a gap of At least 6 months after discontinuing Cholera Vaccine (Inactivated). Please consult your doctor. Dacarbazine may reduce efficacy of Cholera Vaccine (Inactivated).

Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Dacarbazine with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Dacarbazine is essential, ensure a gap of At least 6 months after discontinuing Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). Please consult your doctor. Dacarbazine may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Do not use Dacarbazine with Purified Vi Polysaccharide Typhoid Vaccine. If Dacarbazine is essential, ensure a gap of At least 6 months after discontinuing Purified Vi Polysaccharide Typhoid Vaccine. Please consult your doctor. Dacarbazine may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Severe

Pegfilgrastim (Injection Route)

Do not consume Dacarbazine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor. Dacarbazine may reduce the efficacy of Pegfilgrastim.

Severe

Sargramostim (Injection Route)

Do not consume Dacarbazine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor. Dacarbazine may reduce the efficacy of Sargramostim.

Frequently asked questions

How is Dacazee 200 Injection administered?

Dacazee 200 Injection is administered as infusion or injection. Absorption by mouth is slow and varies, therefore, intravenous (given through vein) infusion or injection administration is preferred.

Is Dacazee 200 Injection a vesicant?

Dacazee 200 Injection is a potent vesicant (it is corrosive), and it should be carefully administered to avoid the risk of extravasation (leaking into the tissues).

What is Dacazee 200 Injection used for?

Dacazee 200 Injection is used to treat skin cancer that has spread to other parts of the body (malignant melanoma), cancer of the white blood cell (Hodgkin's lymphoma) and advanced adult soft tissue sarcomas (cancer of soft tissues such as muscles, tendons, fat, and blood vessels).

How effective is Dacazee 200 Injection?

Dacazee 200 Injection is effective if taken at recommended dosage and duration as advised by your doctor.

Does Dacazee 200 Injection cause hair loss?

Yes, hair loss is a common side effect of Dacazee 200 Injection.

Fact Box

Chemical Class

2- heteroaryl carboxamides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating Agents

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1686-87.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
Dacarbazine citrate. Wedel, Germany: medac GmbH; 1997 [revised Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dacarbazine. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zee Laboratories
Address: Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Dacazee 200 Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dacazee Injection

Benefits of Dacazee Injection

Side effects of Dacazee Injection

How to use Dacazee Injection

How Dacazee Injection works

All substitutes for Dacazee 200 Injection

Dti Korea 200mg Injection

Darzine 200 Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Pegfilgrastim (Injection Route)

Sargramostim (Injection Route)

Frequently asked questions

How is Dacazee 200 Injection administered?

Is Dacazee 200 Injection a vesicant?

What is Dacazee 200 Injection used for?

How effective is Dacazee 200 Injection?

Does Dacazee 200 Injection cause hair loss?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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