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Composition for COVERSYL PLUS

Perindopril(4 mg),Indapamide(1.25 mg)

food interaction for COVERSYL PLUS

alcohol interaction for COVERSYL PLUS

pregnancy interaction for COVERSYL PLUS

lactation interaction for COVERSYL PLUS

There is no data available. Please consult doctor before consuming the drug.
Taking Indapamide with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Coversyl plus tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Perindopril(4 mg)


Perindopril is used to treat high blood pressure (hypertension) heart failure and to prevent heart attack in people with coronary artery disease.

How it works

Perindopril belongs to a class of drugs called as ACE inhibitors. It acts on chemical called angiotensin converting enzyme and thereby relaxing the blood vessels and improving function of heart muscles that pump blood throughout the body.

Common side effects

Abdominal pain, Bloody diarrhea, Cough, Decreased blood pressure, Dizziness, Weakness, Eye swelling, Lip swelling, Headache, Limb swelling, Facial swelling, Throat swelling
Indapamide(1.25 mg)


Indapamide is used alone or in combination with other drugs to treat high blood pressure, and heart failure.

How it works

Indapamide belongs to class of medications called thiazide-like diuretics, it increases urine production from kidney thereby decreasing blood pressure.

Common side effects

Nausea, Paresthesia (tingling or pricking sensation), Rash of purple spots on the skin, Constipation, Dry mouth, Fatigue, Headache, Decreased potassium level in blood, Rash, Vertigo, Vomiting



  • 82%
    Once A Day
  • 15%
    Twice A Day
  • 2%
    Twice A Week
  • 1%
    Thrice A Day


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Expert advice for COVERSYL PLUS

  • Do not take perindopril if you are allergic to it or to any other content in the medicine.
  • Do not take perindopril if you have suffered from acute swelling of the face, tongue or larynx (angioneurtic syndrome), with or without treatment with another ACE inhibitor; diabetes or impaired kidney function.
  • Doctor’s advice should be considered in case of patients with following history of disease conditions: narrowing of heart valves or blood vessels which supply blood to the kidney; heart, liver or kidney problems, diabetes or collagen disease such as scleroderma or systemic lupus erythematosus.
  • Take special precautions while taking perindopril if you are going to have cholesterol removed from your blood by a procedure called as LDL apharesis; if you are receiving treatment for bee allergy or wasp stings.
  • Avoid using perindopril if you are pregnant or planning to become pregnant or breast-feeding.
  • Do not drive or operate heavy machinery when using perindopril as it may lead to dizziness due to low blood pressure.
  • Take perindopril usually in the morning before a meal, to reduce the effect of food on the effectiveness of perindopril.
  • Do not take potassium rich foods with perindopril.

Frequently asked questions for COVERSYL PLUS


Q. Is perindopril a beta-blocker, statin, calcium channel blocker, or an ACE inhibitor?
Perindopril is ACE (angiotensin converting enzyme) inhibitor drug. It is not a beta-blocker, statin, or calcium channel blocker.
Q. Is perindopril the same as perindopril erbumine, perindopril arginine or Coversyl?
Perindopril is the same as perindopril erbumine, perindopril arginine (different salt forms of perindopril with same effects) and Coversyl (brand name of perindopril).
Q. Can I take perindopril with Viagra, ibuprofen, aspirin, naproxen, paracetamol, allupurinol?
Perindopril can be taken with paracetamol and allopurinol only if prescribed by your doctor. Perindopril should not be taken with ibuprofen, aspirin, naproxen, or Viagra (sildenafil).
Q. Does perindopril cause blood thinning?
No, perindopril does not cause thinning of blood; it relaxes the blood vessels thereby decreasing the blood pressure.
Q. Does perindopril cause weight gain, hair loss, tiredness, cough, angiodema, depression, constipation, slow heart rate, or erectile dysfunction?
Perindopril may cause cough, angiodema, depression, tiredness or weakness, constipation or slow heart rate. It is not known to cause weight gain, hair loss, or erectile dysfunction. If you experience any such symptoms, please consult your doctor.


Q. Is indapamide a water pill, beta blocker, calcium channel blocker, loop diuretic, diuretic, angiotensin converting enzyme inhibitor, statins or blood thinner? 
Indapamide is a thiazide-like diuretic, a water pill. It is not a beta blocker, calcium channel blocker, loop diuretic, angiotensin converting enzyme inhibitor, statins or blood thinner.

Q. Is indapamide a sulfa drug, contains sulfa?
Indapamide is a sulfa drug, contains sulfa (sulphonamide). Indapamide should not be taken by patients allergic to sulfa/sulphonamide.

Q. Is indapamide potassium sparing?
Indapamide is not potassium sparing. It lowers the potassium level in body.

Q. Can I take paracetamol, ibuprofen with indapamide?
Ibuprofen may reduce the blood pressure lowering effect of indapamide. Paracetamol can be taken with indapamide. Always consult your doctor before use.

Q. Does indapamide cause weight gain, weight loss, low potassium, hair loss, diabetes, raise blood glucose, gout or erectile dysfunction?
Indapamide does not cause weight gain, hair loss. Indapamide may cause weight loss, low potassium level, diabetes, raise blood glucose, gout or erectile dysfunction.


Content on this page was last updated on 27 June, 2016, by Dr. Varun Gupta (MD Pharmacology)