CORBIS AM TABLET 5MG/2.5MG

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Composition FOR CORBIS AM

Amlodipine(5mg),Bisoprolol(2.5mg)

food interaction for CORBIS AM

alcohol interaction for CORBIS AM

pregnancy interaction for CORBIS AM

lactation interaction for CORBIS AM

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Taking Bisoprolol with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
UNSAFE
Corbis am tablet 5mg/2.5mg may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR CORBIS AM

Amlodipine(5mg)

Uses

Amlodipine is used in the treatment of increased blood pressure and angina.

How it works

Amlodipine is a calcium channel blocker. It blocks the action of calcium on the heart and blood vessels. This lowers the blood pressure, abnormally fast heartbeat and reduces strain on the heart following a heart attack.

Common side effects

Fatigue, Ankle swelling, Sleepiness, Flushing (sense of warmth in the face, ears, neck and trunk), Headache, Nausea, Dizziness, Palpitations, Edema, Abdominal pain.
Bisoprolol(2.5mg)

Uses

Bisoprolol is used in the treatment of angina, arrhythmias, heart attack, increased blood pressure and heart failure.

How it works

Bisoprolol blocks the action of certain chemical messengers on the heart and blood vessels. This effect reduces heartbeat, blood pressure, and strain on the heart following a heart attack.

Common side effects

Nausea, Headache, Fatigue, Dizziness, Palpitations, Constipation, Slow heart rate, Breathlessness, Abdominal pain, Diarrhoea.

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Expert advice FOR CORBIS AM

  • It is very common to have dizziness, lightheadedness, swelling ankles/feet, flushing, or a headache as a side effect.
  • To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
  • Inform your doctor if your symptoms do not improve or if it worsens (for example, your blood pressure readings remain high or increase, chest pain continues or worsens). 
  • Inform your doctor immediately if any of these serious side effects occur: fast/irregular/pounding heartbeat, fainting.
  • Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well.
  • If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose.

Frequently asked questions FOR CORBIS AM

Amlodipine

Q. What is amlodipine used for?
Amlodipine is indicated for the treatment of high blood pressure (hypertension), angina pectoris (pain in the chest caused by blockages in the arteries leading to the heart) or chest pain classed as vasospastic angina pectoris (or Prinzmetal’s angina).
Q. Is amlodipine a calcium channel blocker and how does it works?
Amlodipine is a calcium channel blocker. In patients with high blood pressure, it works by relaxing blood vessels, so that blood passes through them more easily. In patients with angina, it works by improving blood supply to the heart muscle, which then receives more oxygen, and hence, prevents chest pain. It does not provide immediate relief of chest pain from angina.
Q. Is amlodipine safe?
Amlodipine is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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Q. Can I take amlodipine at night?
Amlodipine can be taken at night. You should take amlodipine at the same time each day with a glass of water.
Q. Can I take amlodipine and aspirin?
Amlodipine can be taken with aspirin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take amlodipine with sildenafil?
Both amlodipine and sildenafil cause a lowering the blood pressure. So, taking the two medicines together could be harmful. Please consult your doctor before taking them together.
Q. Is amlodipine a beta blocker?
Amlodipine is not a beta blocker. It belongs to a group of medicines called calcium channel blockers.
Q. Is amlodipine safe for breastfeeding?
It is not known whether amlodipine is passed into breast milk or not. If you are breast-feeding or about to start breastfeeding you must tell your doctor before taking amlodipine. You may need to change the medicine or stop breastfeeding.
Q. Is amlodipine safe for kidneys?
Amlodipine is not known to damage kidneys. However, amlodipine can cause urinary disorders like difficulty in passing urine, increased the need to urinate at night, increased number of times of passing urine as an uncommon side effect.
Q. Is amlodipine a diuretic?
Amlodipine is not a diuretic. It belongs to a group of medicines called calcium channel blockers.
Q. Is amlodipine a blood thinner?
Amlodipine is not a blood thinner. It belongs to a group of medicines called calcium channel blockers.
Q. Is amlodipine a statin?
Amlodipine is not a statin. It belongs to a group of medicines called calcium channel blockers.
Q. Is amlodipine an angiotensin converting enzyme (ACE) inhibitor?
Amlodipine is not an angiotensin converting enzyme (ACE) inhibitor. It belongs to a group of medicines called calcium channel blockers.
Q. Does amlodipine cause tachycardia?
Amlodipine can rarely cause changes in heart rate, which can be an increase (tachycardia) or a decrease in heart rate (bradycardia) or an irregular heart rate. Please consult your doctor if you experience any changes in your heart rate while taking amlodipine.
Q. Does amlodipine cause pedal edema (swelling of the ankles)?
Amlodipine can cause pedal edema (swelling of the ankles). Please consult your doctor if you have pedal edema while taking amlodipine.
Q. Does amlodipine increase creatinine?
Amlodipine has not been reported to increase creatinine levels. Please consult your doctor if you have increased creatinine levels while taking amlodipine as it requires proper diagnosis and management.
Q. Does amlodipine cause erectile dysfunction?
Erectile dysfunction is an uncommon side effect of amlodipine. Please consult your doctor if you experience erectile dysfunction when you are taking amlodipine.
Q. Does amlodipine cause bradycardia (decreased heart rate)?
Amlodipine can rarely cause changes in heart rate, which can be an increase (tachycardia) or a decrease in heart rate (bradycardia) or an irregular heart rate. Please consult your doctor if you experience any changes in your heart rate while taking amlodipine.
Q. Does amlodipine cause weight gain?
Amlodipine can cause changes in weight, it can either cause weight gain or weight loss. However, these changes are very rare. Please consult your doctor if you experience a change in weight while taking amlodipine.
Q. Does amlodipine cause joint pain (arthralgia)?
Amlodipine can cause joint pain (arthralgia). Please consult your doctor if you experience excessive joint pains while taking amlodipine.
Q. Does amlodipine cause cough?
Amlodipine can cause cough, but it is a very rare side effect. Please consult your doctor if you experience excessive coughing while taking amlodipine.
Q. Does amlodipine cause dry mouth?
Amlodipine can cause dry mouth as an uncommon side effect. Please consult your doctor if you experience excessive dryness of mouth after taking amlodipine.
Q. Can I take amlodipine without food?
Amlodipine can be taken before or after food and drinks. Amlodipine should be taken same time each day with a glass of water. Do not take amlodipine with grapefruit juice.
Q. Can I take amlodipine with milk?
There are no specific recommendations on the use of amlodipine with milk. However, it can be taken before or after food and drinks.
Q. Can I take amlodipine with lisinopril?
Amlodipine can be taken with lisinopril. No drug-drug interactions have been reported between the two. However, as both the medicines have a blood pressure lowering effect, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take amlodipine with ibuprofen?
Amlodipine can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions may occur. Please consult your doctor before taking the two medicines together.
Q. Can I take amlodipine with metoprolol?
Amlodipine and metoprolol both have a blood pressure lowering effect. So, taking both the medicines together can be harmful. Please consult your doctor before taking the two medicines together.
Q. Can I take amlodipine with losartan?
Amlodipine and losartan both have a blood pressure lowering effect. So, taking both the medicines together can be harmful. Please consult your doctor before taking the two medicines together.
Q. Can I take amlodipine with ramipril?
Amlodipine and ramipril both have a blood pressure lowering effect. So, taking both the medicines together can be harmful. Please consult your doctor before taking the two medicines together.
Q. Can I take amlodipine with simvastatin?
Amlodipine can increase the levels of simvastatin, causing an increased tendency towards myopathy (muscle pain) and rhabdomyolysis (increased breakdown of muscle). The dose of simvastatin may need to be reduced when giving along with amlodipine. Please consult your doctor.
Q. Can I take amlodipine with atorvastatin?
Amlodipine can be taken with atorvastatin. No drug-drug interactions have been reported between the two. However, interactions may occur as interactions have been reported between simvastatin (belongs to the same class). Please consult your doctor before taking the two medicines together.
Q. Does amlodipine cause gout?
Amlodipine does not cause gout. It may cause joint pains (arthralgia). Please consult your doctor in case you have any signs and symptoms of gout as you may need treatment for the same.

Bisoprolol

Q. Is bisoprolol fumarate same as bisoprolol?
Yes, Bisoprolol fumarate is same as bisoprolol.
Q. Is bisoprolol a beta-blocker?
Yes, bisoprolol is a highly selective beta1-blocker. It blocks the action of certain chemical messengers on the heart and blood vessels. This can lower the blood pressure, abnormally fast heartbeat and reduces strain on the heart following a heart attack.
Q. Is bisoprolol a selective beta-blocker?
Yes, bisoprolol is a highly selective blocker of beta1 adrenergic receptors mainly found in the heart.
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Q. Is bisoprolol cardioselective?
Bisoprolol is a highly selective beta1-blocker. Beta1 receptors are mainly found in heart making bisoprolol a relatively cardioselective beta-blocker. It has very less affinity towards beta 2 receptors.
Q. Is bisoprolol addictive?
Bisoprolol is not known to be an addictive drug.
Q. Is bisoprolol a blood thinner?
No, bisoprolol is not a blood thinner. It is a beta blocker which can lower the blood pressure, abnormally fast heartbeat and reduces strain on the heart following a heart attack.
Q. Is bisoprolol a statin?
No, bisoprolol is not a statin. Statins are a different group of medicines which are used to lower the lipid levels.
Q. Is bisoprolol safe?
Bisoprolol is generally a safe medicine. However, it has its own side effects. It should only be used under a physician's guidance for the appropriate indication.
Q. Is bisoprolol a steroid?
No, bisoprolol is not a steroid. It is a beta-blocker.
Q. Is bisoprolol a nitrate?
No, bisoprolol is not a nitrate. It is a highly selective beta1-blocker and mainly acts on the heart whereas nitrates are substances which cause the dilatation of the blood vessels.
Q. Is bisoprolol lipophilic?
Bisoprolol is equally lipophilic and hydrophilic. That means it is equally soluble in water as well as organic solvents.
Q. Can I take bisoprolol for anxiety?
No, bisoprolol is not indicated for the treatment of anxiety. If you have such symptoms, please consult your doctor.
Q. Can I take bisoprolol with amlodipine?
Bisoprolol, when used with amlodipine, may cause heart-related side effects. If taken together, it should only be done under medical supervision.
Q. Can I take bisoprolol with tadalafil?
When taken together, tadalafil has the potential to increase the blood-pressure-lowering effect of bisoprolol. Kindly consult your doctor before taking these medications together.<br>
Q. Can I take bisoprolol with ramipril?
No interactions have been reported between bisoprolol and ramipril. Please consult your doctor before taking the two medicines together as this should only be done under medical supervision.
Q. Can I take bisoprolol with amitriptyline?
Amitriptyline, when used along with bisoprolol, may lower the blood pressure. If you need to use both the drugs together, consult your doctor.<br>
Q. Can I take bisoprolol with food?
The absorption of bisoprolol is not known to be affected by food. It can be taken irrespective of the timing of food intake. It should preferably be taken in the morning.<br>
Q. Can I take bisoprolol with paracetamol?
Paracetamol is not known to have any clinically meaningful interaction with bisoprolol. However, interactions may exist as paracetamol belongs to the class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) and these can reduce the blood pressure lowering action of bisoprolol. Please consult your doctor before taking the two medicines together.<br>
Q. Can I take bisoprolol with ibuprofen?
Ibuprofen may decrease the blood-pressure-lowering effect of bisoprolol especially when taken in large doses for a prolonged period. Consult your doctor for taking both the medicines together.<br>
Q. Can I take bisoprolol with aspirin?
Aspirin especially when used in high doses with bisoprolol, may reduce the blood-pressure-lowering effect of the latter drug. Non-steroidal anti-inflammatory drugs (NSAIDs; pain killers) may reduce the blood lowering action of bisoprolol. Please consult your doctor while taking the two medicines together.<br>
Q. Does bisoprolol cause insomnia (difficulty to sleep)?
Bisoprolol use has not been commonly associated with insomnia (difficulty to sleep). If you have difficulty in sleeping while using the drug, consult your doctor.
Q. Does bisoprolol cause sweat?
Increased sweating has not been commonly seen as a side effect of bisoprolol therapy. However, it may not warrant discontinuation of therapy. Consult your doctor if you have excessive sweating while taking the drug.<br>
Q. Does bisoprolol cause muscle pain?
Bisoprolol may cause muscle weakness and cramps (pain) in some patients. Consult your doctor if you experience muscle pain or weakness.<br>
Q. Does bisoprolol cause weight gain?
Bisoprolol is not seen to be associated with weight gain. However, it does not mean that weight gain may never occur. If you have any sudden changes in weight, consult your doctor.
Q. Does bisoprolol work immediately?
As with any other drug taken orally, bisoprolol takes some time to reach the blood and to produce an effect in the body. The maximum effect is seen at approximately between 2 to 4 hours after administration.
Q. Does bisoprolol cause constipation?
Bisoprolol may cause constipation in a few patients. If you experience constipation which is affecting your normal life while taking bisoprolol, please consult your doctor.
Q. Does bisoprolol cause nausea?
Bisoprolol has been associated with gastrointestinal adverse effects like nausea, vomiting, diarrhea, and constipation. Consult your doctor if you experience any such symptom.
Q. Does bisoprolol make you breathless?
Though not very common, bisoprolol may cause breathlessness especially if taken by patients with a history of bronchial asthma. Consult your doctor immediately if you experience any such symptoms.
Q. Does bisoprolol affect blood sugar?
Studies have shown that bisoprolol can cause fluctuations in blood sugar levels. It can also hide the symptoms of low blood sugar levels. Please talk to your doctor in case you are asked to take bisoprolol and you have diabetes mellitus.
Q. Is bisoprolol a diuretic?
No, bisoprolol is not a diuretic, it's a beta blocker which selectively blocks the beta receptors found in the heart and certain cells in the kidney.
Q. Does bisoprolol cause tiredness?
Bisoprolol therapy has been associated with tiredness and fatigue. Consult your doctor if you experience excessive tiredness while taking bisoprolol.
Q. Does bisoprolol cause fluid retention (swelling)?
Bisoprolol is not known to cause fluid retention (swelling). If you suspect any such change while taking the medicine, please consult your doctor.
Q. Does bisoprolol cause depression?
Bisoprolol may cause depression (feeling low) in some patients. If you have any symptoms of depression while taking bisoprolol, please consult your doctor.
Q. Does bisoprolol cause dizziness?
Dizziness is a commonly reported side effect with bisoprolol especially when you are starting the therapy. Consult your doctor if you experience dizziness as it may affect your ability to drive or work with a machinery.
Q. Does bisoprolol cause headache?
Bisoprolol may cause a headache, it is a very commonly reported side effect particularly during the initiation of therapy. Consult your doctor if you have repeated episodes of headache while taking the drug.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)