Closin 25mg Tablet
Product introduction
Closin 25mg Tablet is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave).
Closin 25mg Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include hypotension, dry mouth, headache, increased sweating, visual disturbance, and decreased blood pressure. Please consult your doctor if these side effects do not get better or worse.
Before taking this medicine it is important to inform your doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), heart disease, diabetes, Parkinson’s disease, dementia, fits (epilepsy), difficulty in swallowing (dysphagia), or liver problems.
Uses of Closin Tablet
Benefits of Closin Tablet
In Schizophrenia
Closin 25mg Tablet is used to manage symptoms of schizophrenia, especially in people who haven't responded well to other treatments. It helps reduce hallucinations, disorganized thinking, and extreme mood changes, making it easier to think clearly, stay calm, and take part in everyday activities.
Side effects of Closin Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Closin
- Excessive salivation
- Weight gain
- Increased white blood cell count (eosinophils)
- Anticholinergic effects
- Decreased white blood cell count
- Extrapyramidal symptoms
- Dizziness
- Fainting
- Constipation
- Fever
- Increased liver enzymes
- Tachycardia
- Drowsiness
- Seizure
- Fast heart rate
How to use Closin Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Closin 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Closin Tablet works
Closin 25mg Tablet is an atypical antipsychotics. It works by modulating the action of certain chemical messengers in the brain that affects thoughts.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Closin 25mg Tablet.
Pregnancy
SAFE IF PRESCRIBED
Closin 25mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Closin 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Closin 25mg Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Closin 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Closin 25mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Closin 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Closin 25mg Tablet may be needed. Please consult your doctor.
What if you forget to take Closin Tablet?
If you miss a dose of Closin 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Closin 25mg Tablet helps treat schizophrenia in people for whom other medicines are ineffective or not tolerated.
- Take it with or without food, preferably at the same time everyday.
- It can cause dizziness and sleepiness. Be cautious while driving or doing anything that requires concentration.
- It may cause low blood pressure and dehydration. Drink plenty of fluids and rise slowly from a sitting or lying position.
- It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
- Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
- Do not stop taking Closin 25mg Tablet without talking to your doctor first as it may cause worsening of symptoms.
Fact Box
Chemical Class
Dibenzodiazepine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Atypical Antipsychotics
Interaction with drugs
Taking Closin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Domperidone with Clozapine.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Clozapine with Haloperidol. If concurrent use is essential, watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, los
Do not consume Clozapine with Haloperidol. If concurrent use is essential, watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, los
If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes and consult your doctor if you experience them. The
If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes and consult your doctor if you experience them. The
Patient concerns
User feedback
How much was the improvement?
Poor
67%
Average
33%
FAQs
How long does it take for Closin 25mg Tablet to work?
Like many medicines, Closin 25mg Tablet does not work straight away. You might start feeling more calm and relaxed after a few weeks of taking this medicine.
Why has Closin 25mg Tablet been prescribed?
Closin 25mg Tablet is an antipsychotic drug used to treat manic episodes and Schizophrenia, a mood disorder. It shortens the time to recovery and prevents mania from returning. It is also used to reduce the risk of suicidal behavior in people with Schizophrenia.
Does Closin 25mg Tablet help with anxiety?
Yes, Closin 25mg Tablet helps calm the mind and decreases the level of anxiety and aggressive behavior in patients with Schizophrenia.
Is Closin 25mg Tablet addictive?
No, Closin 25mg Tablet is not addictive in nature. No habit-forming potential has been seen with its use. However, always follow your doctor's advice regarding the duration of its use.
When should I see my doctor?
Seek immediate medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction, pain or burning when you urinate, or vaginal itching or discharge.
Can Closin 25mg Tablet cause dizziness?
Yes. Closin 25mg Tablet can cause dizziness by reducing blood pressure. If this happens to you, you should sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while traveling.
Why do I have to have regular blood tests while I am taking Closin 25mg Tablet?
Closin 25mg Tablet is known to cause a rare but serious side effect called “agranulocytosis”. This side effect occurs in less than 1 out of every 100 people who take this medicine. This side effect can result in a decrease in the number of white blood cells (infection-fighting cells) in your body. Without enough white blood cells, your body may not be able to. In order to prevent this, your doctor may prescribe you a blood test to check your white blood cell count.
Can I drink alcohol while taking Closin 25mg Tablet?
It is recommended that people taking this medicine should not drink alcohol. This is because Closin 25mg Tablet is an antipsychotic and taking it with alcohol can cause severe drowsiness. This can lead to falls and accidents. Also, drinking alcohol may make mania, depression, and anxiety worse. Discuss any concerns you have with your doctor, pharmacist, or nurse.
I am experiencing a change in my taste after the start of the treatment with Closin 25mg Tablet. Any tips to reduce it?
A change in taste is a common side-effect of this medicine. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You may also add some extra flavor or seasonings to your food.
I am having trouble remembering to take my medications. Is there anything I can do to help me remember?
In order to avoid missing a dose, use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member a friend to remind you or check in with you to be sure you are taking your medication.
What happens if I stop taking Closin 25mg Tablet?
It is advisable not to stop taking this medicine without talking to your doctor, since it may worsen your symptoms. Your doctor will probably want to decrease your dose gradually.
How long does it take for Closin 25mg Tablet to work?
Like many medicines, Closin 25mg Tablet does not work straight away. You might start feeling more calm and relaxed after a few weeks of taking this medicine.
Why has Closin 25mg Tablet been prescribed?
Closin 25mg Tablet is an antipsychotic drug used to treat manic episodes and Schizophrenia, a mood disorder. It shortens the time to recovery and prevents mania from returning. It is also used to reduce the risk of suicidal behavior in people with Schizophrenia.
Does Closin 25mg Tablet help with anxiety?
Yes, Closin 25mg Tablet helps calm the mind and decreases the level of anxiety and aggressive behavior in patients with Schizophrenia.
Is Closin 25mg Tablet addictive?
No, Closin 25mg Tablet is not addictive in nature. No habit-forming potential has been seen with its use. However, always follow your doctor's advice regarding the duration of its use.
When should I see my doctor?
Seek immediate medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction, pain or burning when you urinate, or vaginal itching or discharge.
Can Closin 25mg Tablet cause dizziness?
Yes. Closin 25mg Tablet can cause dizziness by reducing blood pressure. If this happens to you, you should sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while traveling.
Why do I have to have regular blood tests while I am taking Closin 25mg Tablet?
Closin 25mg Tablet is known to cause a rare but serious side effect called “agranulocytosis”. This side effect occurs in less than 1 out of every 100 people who take this medicine. This side effect can result in a decrease in the number of white blood cells (infection-fighting cells) in your body. Without enough white blood cells, your body may not be able to. In order to prevent this, your doctor may prescribe you a blood test to check your white blood cell count.
Can I drink alcohol while taking Closin 25mg Tablet?
It is recommended that people taking this medicine should not drink alcohol. This is because Closin 25mg Tablet is an antipsychotic and taking it with alcohol can cause severe drowsiness. This can lead to falls and accidents. Also, drinking alcohol may make mania, depression, and anxiety worse. Discuss any concerns you have with your doctor, pharmacist, or nurse.
I am experiencing a change in my taste after the start of the treatment with Closin 25mg Tablet. Any tips to reduce it?
A change in taste is a common side-effect of this medicine. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You may also add some extra flavor or seasonings to your food.
I am having trouble remembering to take my medications. Is there anything I can do to help me remember?
In order to avoid missing a dose, use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member a friend to remind you or check in with you to be sure you are taking your medication.
What happens if I stop taking Closin 25mg Tablet?
It is advisable not to stop taking this medicine without talking to your doctor, since it may worsen your symptoms. Your doctor will probably want to decrease your dose gradually.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Clozapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 153-59.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 308-309.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
- Clozapine. East Hanover, New Jersey: Novartis Pharmaceuticals; 2004. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Clozapine [Patient Information Leaflet]. Ahmedabad, Gjjarat: Torrent Pharmaceuticals Ltd.; 2014. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Durpha Lifesciences
Address: 709, 7th floor, mansarovar plaza madhyam marg, mansarovar, jaipur-302020 (india)
Country of origin: India
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