Clofalon 20mg Injection

Clofarabine (20mg)

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Clofalon 20mg Injection is used to treat children, teenagers and young adults with a type of blood cancer called acute lymphoblastic leukemia (ALL). It is used when previous treatments have not worked or have stopped working. It may be also used to treat some other conditions.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)

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General Information

Contains

Clofarabine (20mg)

Marketer

Celon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Clofalon 20mg Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, and rash. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Clofalon Injection

Blood cancer (Acute lymphocytic leukemia)

Benefits of Clofalon Injection

Blood cancer (Acute lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Clofalon 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Clofalon Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clofalon

Nausea
Vomiting
Diarrhea
Headache
Rash
Itching
Fever due to low white blood cell count (neutrophils)
Fatigue
Anxiety
Flushing (sense of warmth in the face, ears, neck and trunk)
Mucosal inflammation

How to use Clofalon Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Clofalon Injection works

Clofalon 20mg Injection is an anticancer medication. It works by preventing the multiplication of the abnormal white blood cells. It does so by suppressing the production of the cells' genetic material, DNA. Cancer cells require DNA for growth and multiplication.

All substitutes for Clofalon 20mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Farabine 20mg Injection

by Intas Pharmaceuticals Ltd

₹9765.62/injection

7% cheaper

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Clofalon 20mg Injection. Please consult your doctor.

Pregnancy

UNSAFE

Clofalon 20mg Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Clofalon 20mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Clofalon 20mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Clofalon 20mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Clofalon 20mg Injection in patients with liver disease.

Interaction with drugs

Taking Clofalon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Pegfilgrastim (Injection Route)

Do not consume Clofarabine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.

Life-threatening

Sargramostim (Injection Route)

Do not consume Clofarabine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.

Life-threatening

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.

Life-threatening

Molgramostim (Injection Route)

Do not consume Clofarabine from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.

Life-threatening

Natalizumab (Injection Route)

Do not consume Natalizumab with Clofarabine.

Frequently asked questions

What is Clofalon 20mg Injection and what it is used for?

Clofalon 20mg Injection is an anti-cancer medication used for the treatment of a certain kind of blood cancer in children and young adults 1 to 21 years old.

When should I call my doctor right away?

Get medical help right away if you have signs of allergic reaction such as difficulty breathing, rash, hives, itching, and blisters. Also, let your doctor know if you experience severe fast heartbeats, diarrhea that is watery or bloody, little or no urination, upper stomach pain, fever, chills.

Can Clofalon 20mg Injection damage my liver?

Clofalon 20mg Injection may affect the liver and cause serious or even life-threatening damage to the liver. Inform your doctor immediately if you notice severe stomach pain (upper right side), dark urine, clay-colored stools, tiredness, itching, or jaundice (yellowing of the skin or eyes).

I am experiencing nausea and extreme tiredness. Is this due to Clofalon 20mg Injection?

Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

How to get relief from diarrhea while on treatment with Clofalon 20mg Injection?

Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), orange, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.

I have noticed some changes in my skin after taking Clofalon 20mg Injection. What should I do?

Use a moisturizer to get relief from rashes, dry, and itchy skin during the treatment. Avoid sun exposure. Wear SPF 30 (or higher) sunblock and protective clothing. However, if you develop yellow discoloration of your skin, inform your doctor immediately as this could be a sign of a liver problem.

I can sense slight warmth in my face, ears, and neck. is this normal?

Yes, this is normal and will start to get better when treatment ends. Try to keep your body cool by using a fan, cooler, or air conditioner and avoid tight-fitting clothes.

Should I avoid any food and drinks while taking Clofalon 20mg Injection?

You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eating small, simple but nourishing snacks every few hours rather than large meals, and sucking on hard candy or popsicles to prevent nausea and vomiting.

What should I avoid during my treatment with Clofalon 20mg Injection?

During your treatment, it is advisable to avoid caffeine as it can make you feel dehydrated, avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea, avoid alcohol and smoking. It is also advisable to avoid crowds or people with colds, as you may be at risk of infection as well as sun exposure to prevent rashes and dry skin. Do not have immunizations/vaccinations without the consent of your doctor. Use caution with sharp objects like razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised, or injured.

Fact Box

Chemical Class

Purine 2'- deoxyribonucleosides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1704.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 294-95.
Clofarabine. Cambridge, MA: Genzyme Corporation; 2004. [Accessed 26 Mar. 2019] (online) Available from:
Clofarabine. [Accessed 26 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Clofalon 20mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Clofalon Injection

Benefits of Clofalon Injection

Side effects of Clofalon Injection

How to use Clofalon Injection

How Clofalon Injection works

All substitutes for Clofalon 20mg Injection

Farabine 20mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pegfilgrastim (Injection Route)

Sargramostim (Injection Route)

Lenograstim (Injection Route)

Molgramostim (Injection Route)

Natalizumab (Injection Route)

Frequently asked questions

What is Clofalon 20mg Injection and what it is used for?

When should I call my doctor right away?

Can Clofalon 20mg Injection damage my liver?

I am experiencing nausea and extreme tiredness. Is this due to Clofalon 20mg Injection?

How to get relief from diarrhea while on treatment with Clofalon 20mg Injection?

I have noticed some changes in my skin after taking Clofalon 20mg Injection. What should I do?

I can sense slight warmth in my face, ears, and neck. is this normal?

Should I avoid any food and drinks while taking Clofalon 20mg Injection?

What should I avoid during my treatment with Clofalon 20mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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