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Farabine 20mg Injection

Prescription Required

Product introduction

Farabine 20mg Injection is used to treat children, teenagers and young adults with a type of blood cancer called acute lymphoblastic leukemia (ALL). It is used when previous treatments have not worked or have stopped working. It may be also used to treat some other conditions.

Farabine 20mg Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, and rash. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Farabine Injection

  • Blood cancer (Acute lymphocytic leukemia)

Benefits of Farabine Injection

In Blood cancer (Acute lymphocytic leukemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Farabine 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Farabine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Farabine

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Rash
  • Itching
  • Fever due to low white blood cell count (neutrophils)
  • Fatigue
  • Anxiety
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Mucosal inflammation

How to use Farabine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Farabine Injection works

Farabine 20mg Injection is an anticancer medication. It works by preventing the multiplication of the abnormal white blood cells. It does so by suppressing the production of the cells' genetic material, DNA. Cancer cells require DNA for growth and multiplication.

Safety advice

Alcohol
UNSAFE
Farabine 20mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Farabine 20mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Farabine 20mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Farabine 20mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Farabine 20mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Farabine 20mg Injection may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Farabine 20mg Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Farabine 20mg Injection
₹10099/Injection
Clofalon 20mg Injection
Celon Laboratories Ltd
₹11199/injection
8% costlier

Quick tips

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class
Purine 2'-deoxyribonucleosides Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites

Interaction with drugs

Taking Farabine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Clofarabine from 1 day before until 1 day after taking Sargramostim. P... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Clofarabine from 14 days before until 24 days after taking Pegfilgrast... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Clofarabine from 1 day before until 1 day after taking Molgramostim. P... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot... More
Concomitant use may increase the risk of opportunistic infections. Do not consume Natalizumab with Clofarabine.

Patient concerns

arrow
I want to know about Acute Lymphoblastic Leukemia CNS Relapse protocol followed by standard doctors.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
What you want know
Features suggestive of acute myeloid leukemia Is this disease is curable if no than how much time did the patient have with & without treatment
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Less chances of cureHowever treatment is possible
arrow

FAQs

What is Farabine 20mg Injection and what it is used for?

Farabine 20mg Injection is an anti-cancer medication used for the treatment of a certain kind of blood cancer in children and young adults 1 to 21 years old.

When should I call my doctor right away?

Get medical help right away if you have signs of allergic reaction such as difficulty breathing, rash, hives, itching, and blisters. Also, let your doctor know if you experience severe fast heartbeats, diarrhea that is watery or bloody, little or no urination, upper stomach pain, fever, chills.

Can Farabine 20mg Injection damage my liver?

Farabine 20mg Injection may affect the liver and cause serious or even life-threatening damage to the liver. Inform your doctor immediately if you notice severe stomach pain (upper right side), dark urine, clay-colored stools, tiredness, itching, or jaundice (yellowing of the skin or eyes).

I am experiencing nausea and extreme tiredness. Is this due to Farabine 20mg Injection?

Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

How to get relief from diarrhea while on treatment with Farabine 20mg Injection?

Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), orange, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.

I have noticed some changes in my skin after taking Farabine 20mg Injection. What should I do?

Use a moisturizer to get relief from rashes, dry, and itchy skin during the treatment. Avoid sun exposure. Wear SPF 30 (or higher) sunblock and protective clothing. However, if you develop yellow discoloration of your skin, inform your doctor immediately as this could be a sign of a liver problem.

I can sense slight warmth in my face, ears, and neck. is this normal?

Yes, this is normal and will start to get better when treatment ends. Try to keep your body cool by using a fan, cooler, or air conditioner and avoid tight-fitting clothes.

Should I avoid any food and drinks while taking Farabine 20mg Injection?

You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eating small, simple but nourishing snacks every few hours rather than large meals, and sucking on hard candy or popsicles to prevent nausea and vomiting.

What should I avoid during my treatment with Farabine 20mg Injection?

During your treatment, it is advisable to avoid caffeine as it can make you feel dehydrated, avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea, avoid alcohol and smoking. It is also advisable to avoid crowds or people with colds, as you may be at risk of infection as well as sun exposure to prevent rashes and dry skin. Do not have immunizations/vaccinations without the consent of your doctor. Use caution with sharp objects like razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised, or injured.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1704.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 294-95.
  3. Clofarabine. Cambridge, MA: Genzyme Corporation; 2004. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Clofarabine. [Accessed 26 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
Expires on or after: March, 2025

A licensed vendor partner from your nearest location will deliver Farabine 20mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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1.0 Injection in 1 vial
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