Bulocel 0.5 Injection

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 14 Apr 2026 | 04:20 PM (IST)

Bulocel 0.5 Injection is a prescription medication used as a local anesthetic. It is used during minor surgical procedures such as dental, oral, diagnostic, or other therapeutic procedures to anesthetize or numb the surgical area. This medicine can also be useful in the relief of pain, e.g., during labor.

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General Information

Contains

Bupivacaine (5mg/ml)

Marketer

Celon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Bulocel 0.5 Injection blocks the nerve impulses that send pain signals to your brain and helps to perform a painless procedure by temporarily numbing the surgical area.

Like many other medicines, this medicine also has few side effects. The most common side effects of this medicine are nausea, vomiting, tingling sensation, slow heart rate, high or low blood pressure, dizziness, and urinary retention. These are usually mild and short-lived. If the numbness or other side effects persist, consult your doctor without delay.

Before using Bulocel 0.5 Injection, it is very important to tell your doctor if you have any underlying heart disease or are taking medicines for heart rhythm problems. Let your doctor know if you are pregnant or breastfeeding. Also, it is not safe to drive or operate heavy machinery while on medication, unless your doctor permits you to do so.

Uses of Bulocel Injection

Local anesthesia (Numb tissues in a specific area)

Benefits of Bulocel Injection

Local anesthesia (Numb tissues in a specific area)
Local anesthesia is often required during minor surgical procedures to block pain in a specific area without affecting consciousness. Bulocel 0.5 Injection is used as a local anesthetic to numb the surgical site, helping prevent pain and discomfort during procedures such as dental treatments, minor surgeries, or diagnostic interventions. This allows patients to undergo the procedure comfortably and recover more smoothly.

Side effects of Bulocel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bulocel

Nausea
Vomiting
Paresthesia (tingling or pricking sensation)
Slow heart rate
Decreased blood pressure
High blood pressure
Dizziness
Urinary retention

How to use Bulocel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bulocel Injection works

Bulocel 0.5 Injection is a local anesthetic. It works by blocking the transmission of pain signals from the nerves to the brain. This helps to decrease the sensation of pain.

Quick tips

Bulocel 0.5 Injection is given as an injection by the healthcare professional.
It may affect your concentration or make you feel sleepy, so avoid driving or using tools or machines until the next day.
Consult your doctor immediately if you experience dizziness, lightheadedness, problem with sight or hearing or numbness around lips, tongue and mouth.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bulocel 0.5 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Bulocel 0.5 Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Bulocel 0.5 Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

CONSULT YOUR DOCTOR

It is not known whether Bulocel 0.5 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Bulocel 0.5 Injection may cause numbness to certain areas of the body for about 2-4 hours after having it. You should wait for the effect to wear off as this may affect your ability to drive

Kidney

SAFE IF PRESCRIBED

Bulocel 0.5 Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

CAUTION

Bulocel 0.5 Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Bulocel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Mild

Captopril (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Monitoring of blood pressure is recommended.

Mild

Diazepam (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Diazepam may raise blood levels of Bupivacaine.

Mild

Diazepam (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Diazepam may raise blood levels of Bupivacaine.

Mild

Indomethacin (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Indomethacin may reduce efficacy of Bupivacaine.

Mild

Indomethacin (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Indomethacin may reduce efficacy of Bupivacaine.

Frequently asked questions

Is Bulocel 0.5 Injection an opioid or narcotic?

No, Bulocel 0.5 Injection is neither an opioid nor a narcotic. Bulocel 0.5 Injection is a medication that belongs to a class of medicines known as local anesthetics. It helps prevent pain which occurs during and after a surgery. The effect of the medicine lasts for over a long period of time, thus aiding in recovery too. Bulocel 0.5 Injection works on your body only in the treated area, unlike opioids that work on the whole body.

How does Bulocel 0.5 Injection work?

Bulocel 0.5 Injection works by numbing that area on your body where a surgery has been performed. Bulocel 0.5 Injection slowly releases a local anesthetic medication into that area, thus providing effective long-lasting pain relief.

Will I need other medicines other than Bulocel 0.5 Injection for pain relief?

Yes, your doctor may prescribe some other pain relieving medicines alongwith Bulocel 0.5 Injection for effective pain management. Due to this, you will need lower doses of the different medicines you are taking. Additionally, this will also reduce the chances of developing side effects of a particular medicine because of the lower doses.

Is Ropivacaine safer than Bulocel 0.5 Injection?

Ropivacaine is a left isomer of Bulocel 0.5 Injection. Yes, Ropivacaine is comparatively safer than Bulocel 0.5 Injection. There are less toxic effects of ropivacaine on the heart and central nervous system as compared to Bulocel 0.5 Injection. Hence, it is considered as a safer option.

What are the early symptoms of local anesthesia toxicity?

Our nervous system is more sensitive to the effects of local anesthetics than any other system of the human body. In case of local anesthesia toxicity one may experience tinnitus (ringing sound in the ears), blurred vision, dizziness, tongue paresthesia (tingling or pricking sensation) and circumoral numbness (numbness around the eyes). Consult your doctor if the symptoms bothers you.

Fact Box

Chemical Class

Alpha amino acid amides

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Amide-Type Local Anesthetics

References

Catterall WA, Mackie K. Local Anesthetics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 573.
Bupivacaine. Lake Forest, Illinois: Hospira, Inc; 2011. [Accessed 05 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 05 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India

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Bulocel 0.5 Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Bulocel Injection

Benefits of Bulocel Injection

Side effects of Bulocel Injection

How to use Bulocel Injection

How Bulocel Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Captopril (Oral Route)

Diazepam (Oral Route)

Diazepam (Injection Route)

Indomethacin (Injection Route)

Indomethacin (Oral Route)

Frequently asked questions

Is Bulocel 0.5 Injection an opioid or narcotic?

How does Bulocel 0.5 Injection work?

Will I need other medicines other than Bulocel 0.5 Injection for pain relief?

Is Ropivacaine safer than Bulocel 0.5 Injection?

What are the early symptoms of local anesthesia toxicity?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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