Buflex 500mg Tablet

Nabumetone (500mg)

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Buflex 500mg Tablet is a pain-relieving medicine. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis and osteoarthritis.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 20 Dec 2025 | 01:00 AM (IST)

₹112 MRP ₹126.5612% off

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General Information

Contains

Nabumetone (500mg)

Marketer

Zubex Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Buflex 500mg Tablet should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke.

The common side effects of this medicine include diarrhea, indigestion, abdominal pain, constipation, flatulence, nausea, dizziness, headache, itching, rash, ringing ears, and edema. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components, if you are taking this medicine for long-term treatment. Long term use may lead to serious complications such as stomach bleeding and kidney problems.

Uses of Buflex Tablet

Pain relief

Benefits of Buflex Tablet

Pain relief
Buflex 500mg Tablet belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to relieve pain, inflammation and swelling in painful conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life. Mild symptoms of osteoarthritis can sometimes be managed by simple measures such as regular exercise, losing weight, good posture, and wearing suitable footwear.

Side effects of Buflex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Buflex

Diarrhea
Indigestion
Abdominal pain
Constipation
Flatulence
Nausea
Dizziness
Headache
Rash
Itching
Ringing in ear
Edema (swelling)

How to use Buflex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Buflex 500mg Tablet should be taken with or after food.

How Buflex Tablet works

Buflex 500mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Quick tips

You have been prescribed Buflex 500mg Tablet to relieve pain and inflammation.
Take it with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
Avoid consuming alcohol while taking Buflex 500mg Tablet as it can cause excessive drowsiness and increase your risk of stomach problems.
Inform your doctor if you have a history of heart disease or stroke.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Buflex 500mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Buflex 500mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Buflex 500mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Buflex 500mg Tablet may cause side effects that could affect your ability to drive.
As may feel dizzy, tired, have problems with your vision or have headaches after taking Buflex 500mg Tablet and this may affect your ability to drive.

Kidney

CAUTION

Buflex 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Kidney function tests and some other blood tests may advised when you will start with this therapy and then at regular intervals while you are taking this medicine.

Liver

CAUTION

Buflex 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Buflex 500mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Buflex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Is Buflex 500mg Tablet an antibiotic or steroid?

No, Buflex 500mg Tablet is neither an antibiotic nor a steroid. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines. It is used to relieve moderate to severe pain and inflammation.

Is Buflex 500mg Tablet a good painkiller?

Buflex 500mg Tablet is effective in relieving pain and inflammation. It is used to provide relief from various sorts of pain, such as sprains, strains and other injuries. It is also helpful in the treatment of different types of arthritis and gout. Along with that, it can be used to reduce pain and inflammation which follows after a surgery.

Is Buflex 500mg Tablet safe?

Buflex 500mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

What if I forget to take a dose of Buflex 500mg Tablet?

If you forget a dose of Buflex 500mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Is Buflex 500mg Tablet effective?

Buflex 500mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Buflex 500mg Tablet too early, the symptoms may return or worsen.

What are the side effects of Buflex 500mg Tablet?

Some common side effects associated with Buflex 500mg Tablet vomiting, stomach pain, nausea and indigestion. However, these side effects are usually not bothersome and resolve in some time. If they persist for a longer duration or worry you, consult your doctor.

Fact Box

Chemical Class

Naphthalene derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)

References

Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 986.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 947.
Nabumetone. Research Triangle Park, North Carolina: GlaxoSmithKline. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zubex Pharmaceuticals
Address: A-17 Shane-Burhan Society, Near Sheikh & Co, Juhapura Road, Ahmedabad.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Buflex 500mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Buflex Tablet

Benefits of Buflex Tablet

Side effects of Buflex Tablet

How to use Buflex Tablet

How Buflex Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

Is Buflex 500mg Tablet an antibiotic or steroid?

Is Buflex 500mg Tablet a good painkiller?

Is Buflex 500mg Tablet safe?

What if I forget to take a dose of Buflex 500mg Tablet?

Is Buflex 500mg Tablet effective?

What are the side effects of Buflex 500mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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