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Composition FOR BOZETAN

Bosentan(125 mg)

food interaction for BOZETAN

alcohol interaction for BOZETAN

pregnancy interaction for BOZETAN

lactation interaction for BOZETAN

medicine interaction for BOZETAN

It can be taken with or without food, but it is better to take Bozetan 125mg tablet at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Bozetan 125mg tablet is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
Bozetan 125mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Bosentan(125 mg)


Bozetan 125mg tablet is used in the treatment of pulmonary hypertension (high pressure in the blood vessels of lungs)

How it works

Bozetan 125mg tablet relaxes blood vessels of the lungs which lowers their blood pressure.

Common side effects

Nasal congestion, Sinus inflammation, Respiratory tract infection, Peripheral edema, Flushing, Anemia


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Expert advice FOR BOZETAN

  • Bosentan controls the symptoms of pulmonary arterial hypertension but does not cure it. It may take 1-2 months or longer before you experience the full benefit of bosentan.
  • Do not stop taking bosentan suddenly even if you feel well as this may worsen your symptoms.
  • You may have to undergo regular blood test every month during the treatment to check for anemia (low hemoglobin) and liver function.
  • Do not drive or operate any tools or machines while using bosentan, as it may cause dizziness affecting your ability to drive and use machines.
  • While taking bosentan, women must use a highly effective form of birth control or two methods together (example, contraceptive pills plus barrier method) to prevent pregnancy during treatment.

Frequently asked questions FOR BOZETAN


Q. What is bosentan used for/ what is bosentan therapy?
Bosentan is used in adults and children to treat high blood pressure in the vessels that carry blood to the lungs (pulmonary arterial hypertension). It is also used in adults for the treatment of painful and difficult to heal open sores on fingers and toes (digital ulcers)

Q. Does bosentan work?
Bosentan is effective if taken at recommended dosage and duration as advised by your doctor

Q. Is bosentan an orphan drug?
Yes, bosentan is an orphan drug

Q. Is bosentan cytotoxic?
Bosentan is not a cytotoxic drug. However, studies have shown that bosentan induces liver injury by accumulation of cytotoxic bile salts

Q. Is bosentan available in India?
Yes, it is available in India.


Content on this page was last updated on 12 January, 2017, by Dr. Varun Gupta (MD Pharmacology)