Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Interaction with drugs
Patient concerns
FAQs

Author Details

Written By

Dr. Lipika Khurana

PGDHHM, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

16 Apr 2025 | 10:36 PM (IST)

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Bile Forte 300mg Tablet

Prescription Required

Marketer

Skiptuit Healthcare

SALT COMPOSITION

Ursodeoxycholic Acid (300mg)

Storage

Store below 30°C

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

Bile Forte 300mg Tablet is a medicine used to dissolve certain gallstones and prevent them from forming. It helps break down the cholesterol that has converted into stones in your gallbladder, thereby dissolving the stones. It is also used to treat a type of liver disease called primary biliary cirrhosis.

Bile Forte 300mg Tablet should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your health condition. Take it regularly to get maximum benefit, and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.

The most common side effects of Bile Forte 300mg Tablet are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them or they do not go away, let your doctor know. They may be able to suggest ways to manage them or prescribe an alternative medicine.

Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, frequent cramp-like pain in your upper abdomen, coughing up blood, or gaining weight rapidly. Using this medicine can reduce or increase the effect of some other medicines, so tell your doctor about all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctor before using this medicine to make sure it is safe for them.

Uses of Bile Tablet

Treatment of Gallbladder stones
Treatment of Primary biliary cirrhosis

Benefits of Bile Tablet

In Treatment of Gallbladder stones

Bile Forte 300mg Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

In Treatment of Primary biliary cirrhosis

Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Bile Forte 300mg Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

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Side effects of Bile Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bile

Abdominal pain
Diarrhea
Hair loss
Itching
Nausea
Rash

How to use Bile Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bile Forte 300mg Tablet is to be taken with food.

How Bile Tablet works

Bile Forte 300mg Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Bile Forte 300mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Bile Forte 300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Bile Forte 300mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

SAFE

Bile Forte 300mg Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Bile Forte 300mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Bile Forte 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bile Forte 300mg Tablet may be needed. Please consult your doctor.

What if you forget to take Bile Tablet?

If you miss a dose of Bile Forte 300mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Bile Forte 300mg Tablet

₹28.8/Tablet

Ursolid 300mg Tablet

Leeford Healthcare Ltd

₹25.9/tablet

10% cheaper

Udinol 300mg Tablet

Knoll Pharmaceuticals Ltd

₹37.2/tablet

29% costlier

Udiliv 300 Tablet

Abbott

₹55.47/tablet

93% costlier

actibILE 300 Tablet

Zydus Cadila

₹45.5/tablet

58% costlier

Ursetor 300 Tablet

Torrent Pharmaceuticals Ltd

₹43.2/tablet

50% costlier

View all substitutes

Quick tips

Bile Forte 300mg Tablet should be taken after a meal with a glass of milk or water.
Eat a healthy diet, exercise regularly, and avoid alcohol intake.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy and every 6 months thereafter.
Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class

Bile Acids and Salts

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotective Agents

Interaction with drugs

Taking Bile with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Allylestrenol (Oral Route) Moderate

Careful consideration is advised when taking Ursodeoxycholic Acid with Allylestrenol. Your doctor may monitor your treatment and adjust the doses as per the observations. Concurre... More

Bezafibrate (Oral Route) Moderate

Do not consume Ursodeoxycholic Acid with Bezafibrate. If concurrent use is essential, your doctor may monitor the effects of Ursodeoxycholic Acid along with your overall treatment ... More

Cholestyramine (Oral Route) Moderate

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Cholestyramine. Your doctor may monitor the effects of Ursodeoxycholic Acid. Cholestyramine may reduce bloo... More

Colesevelam (Oral Route) Moderate

Ensure a gap of at least 4 hours between taking Ursodeoxycholic Acid and Colesevelam. Your doctor may monitor your treatment and adjust the doses as per the observations. Colesevel... More

Magaldrate (Oral Route) Moderate

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Magaldrate. Magaldrate may decrease the absorption of Ursodeoxycholic Acid.

View all drug interactions

Patient concerns

Hi, my mother is having stomach pain from last 3 days, has already given the pain killers, pantop d, oflox oz etc. Ultrasound report is attached but radiologist couldn't see the end part of gallbladder and not sure due to gastric or a stone but the way is obstructed. Please suggest the next step Fever is around 100 to 101

Dr. Sfurti Mann

Internal Medicine

Please consult a gastro enterologist as MRCP may be required of there is obstruction in the bile duct.

GGT&ALP increased what resion of that and interpretation

Dr. Ila Jain Khandelwal

Pathology

Dear PATIENT and ALP are liver enzymes which get raised in case of liver injury. Thy can be raised to excessive alcohol intake, bile duct obstruction like gall bladder stones etc.

ALP Levels in my test are high Alkaline Phosphatase (ALP) 222H -- Ref Range: 45 - 129 Although my remaining liver profile is normal. ALP has been increasing. 6 months back it was ~150 Can you please assist me with this. Thanks

Dr. Ila Jain Khandelwal

Pathology

Dear PATIENT ALP can be due to multiple causes, the most important being obstruction in bile duct. You can get a Ultrasound abdomen done as well.

When should I take Bile Forte 300mg Tablet?

The suitable timing of taking this medicine might differ depending on your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest taking the last dose at bedtime. Bile Forte 300mg Tablet should be taken with water or milk after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night.

Is Bile Forte 300mg Tablet safe?

Bile Forte 300mg Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose, and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

How does Bile Forte 300mg Tablet help the liver?

Bile Forte 300mg Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Does Bile Forte 300mg Tablet cause weight gain?

Yes, there is a chance of weight gain with Bile Forte 300mg Tablet, but it is not common. The use of Bile Forte 300mg Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in the small bile ducts of the liver. In such conditions, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending on the disease, so consult your doctor if you experience weight gain.

What should I avoid while taking Bile Forte 300mg Tablet?

While taking Bile Forte 300mg Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Bile Forte 300mg Tablet. You should also avoid medicines like cholestyramine or colestipol, as they affect the effectiveness of Bile Forte 300mg Tablet. Ask your doctor about the time gap that should be maintained between Bile Forte 300mg Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones, and blood cholesterol-lowering agents such as clofibrate, as they may increase the chances of developing gallstones and act opposite to the Bile Forte 300mg Tablet.

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Related lab tests

Liver Function Test

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Ursodiol [Prescribing Information]. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 2013. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Ursodeoxycholic [Package Insert]. Mumbai, India: Alkem Laboratories Ltd.; 2016. [Accessed 07 Aug. 2023]. (online) Available from:
The Lancet. Gastroenterology and Hepatology. [Accessed 07 Aug. 2023]. (online) Available from:
Ursodeoxycholic Acid [Package Insert]. Hertfordshire, UK: Glenmark Pharmaceuticals Europe Limited; 2019. [Accessed 03 Feb. 2025]. (online) Available from: