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Betnesam Injection 1
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Betnesam Injection

Betamethasone (4mg/ml)
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Betnesam Injection is a medicine used to treat severe asthma attacks, serious allergic reactions, and certain inflammatory conditions affecting soft tissues. It is also used in the management of acute adrenal crisis and severe shock. It works by reducing inflammation and excessive immune responses.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 04 Nov 2026 | 01:59 AM (IST)
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Betnesam Injection 1
Betnesam Injection 2
Betnesam Injection 3
Betnesam Injection 4

Product introduction

Betnesam Injection is generally administered by a healthcare professional in the dose and duration prescribed by your doctor. The number of injections and the length of treatment depend on your condition, its severity, and your response to treatment. Follow your doctor's instructions carefully and do not miss scheduled doses. If you are receiving this medicine for the long term, do not stop treatment suddenly without consulting your doctor, as the dose may need to be reduced gradually.


There is limited information available on the common side effects of Betnesam Injection. However, it may cause side effects such as stomach discomfort, mood changes, difficulty sleeping, increased appetite, and fluid retention in some people. It may also increase blood sugar levels and blood pressure, particularly with repeated or prolonged treatment. Long-term use may increase the risk of infections, thinning of bones, and other corticosteroid-related complications.


Before receiving Betnesam Injection, inform your doctor if you have diabetes, high blood pressure, heart disease, liver or kidney problems, osteoporosis, glaucoma, stomach ulcers, or a history of infections such as tuberculosis. This medicine should not be used in patients with certain untreated systemic infections or known allergies to its ingredients.


Tell your doctor if you are pregnant, breastfeeding, or taking other medicines, including blood thinners and anti-inflammatory medicines. Avoid close contact with people who have chickenpox or shingles if you have not previously had these infections, and seek medical advice if exposure occurs.

Uses of Betnesam Injection

Benefits of Betnesam Injection

Treatment of Severe allergic reactions
Severe allergic reactions can cause widespread inflammation, swelling, skin reactions, and breathing difficulties. Betnesam Injection helps reduce the body’s inflammatory response to allergens. This helps relieve inflammation-related symptoms and swelling. In life-threatening allergic reactions such as anaphylaxis, it is used only as an additional treatment when considered appropriate and does not replace adrenaline or other emergency care.
Treatment of Severe Asthma
A severe asthma attack can cause intense airway inflammation, wheezing, coughing, and difficulty breathing. Betnesam Injection helps reduce inflammation and swelling in the airways, making breathing easier. It can help improve symptoms such as wheezing, chest tightness, and breathlessness.
Treatment of Acute Adrenal Crisis
Acute adrenal crisis is a serious condition that occurs when the body does not have enough corticosteroid hormones to cope with physical stress. It can cause severe weakness, low blood pressure, vomiting, and potentially life-threatening complications. Betnesam Injection provides corticosteroid activity to help compensate for the hormone deficiency during an emergency. It is administered as part of urgent hospital treatment to help stabilise the patient’s condition, alongside other necessary supportive measures.
Treatment of Severe Shock
Severe shock is a life-threatening condition in which blood circulation becomes inadequate to meet the body's needs. It may occur after major injury, surgery, or overwhelming infection and can lead to organ damage. Betnesam Injection provides corticosteroid effects that may support the management of selected patients as part of emergency treatment. It does not directly restore blood circulation or replace essential treatments such as fluids, medicines to support blood pressure, or treatment of the underlying cause.
Treatment of Soft Tissue Inflammatory conditions
Soft tissue inflammatory conditions, such as tennis elbow, tenosynovitis, and bursitis, can cause pain, tenderness, swelling, and difficulty moving the affected area. Betnesam Injection helps reduce inflammation in the affected tissues, helping relieve pain and swelling. This helps movements more comfortable and improve the ability to perform daily activities.

Side effects of Betnesam Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Betnesam
  • Limited data available

How to use Betnesam Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Betnesam Injection works

Betnesam Injection is a corticosteroid medicine that works by reducing the production and release of substances responsible for inflammation and allergic reactions. It helps decrease swelling, redness, and irritation in affected tissues. It also provides corticosteroid activity when the body does not produce enough of these hormones.

Quick tips

  • If you are receiving this medicine for a severe asthma attack, follow your prescribed asthma treatment plan after recovery. Identify and avoid triggers such as dust, smoke, air pollution, and pollen that may worsen your breathing problems.
  • If you have severe allergies, try to identify and avoid substances that trigger your allergic reactions, such as certain foods, medicines, or insect stings.
  • If you receive this medicine for inflammation around a joint or tendon, rest the affected area for 24–48 hours after the injection, and gradually resume normal activities.
  • If you require repeated or prolonged corticosteroid treatment, eat a balanced diet containing calcium- and vitamin D-rich foods, such as milk, curd, and fortified foods, to support bone health.
  • If you have diabetes, monitor your blood sugar levels as advised by your doctor, as corticosteroids may increase blood sugar.
  • Get adequate rest and maintain good personal hygiene during treatment. Corticosteroids can reduce your body’s ability to fight infections, particularly when used in high doses or for prolonged periods.
  • If you are receiving Betnesam Injection for a prolonged period, do not stop it suddenly without consulting your doctor. Your doctor may gradually reduce the dose to allow your body to adjust.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Betnesam Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Betnesam Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Betnesam Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Betnesam Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Betnesam Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CAUTION
Betnesam Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Betnesam with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Betamethasone before taking Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Infliximab (Injection Route)

You should watch for any unusual signs and symptoms of infection and report it to the doctor. Your doctor may monitor the blood cell counts and other investigations of infection.
Severe

Cholera Vaccine (Inactivated) (Oral Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Betamethasone before taking Cholera Vaccine (Inactivated). Cholera Vaccine (Inactivated) may raise blood levels of Betamethasone and its active form.
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Betamethasone before taking Purified Vi Polysaccharide Typhoid Vaccine.
Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

Betnesam Injection is used to treat severe asthma attacks, serious allergic reactions, and certain inflammatory conditions affecting soft tissues. It is also used ka wrzopc acute adrenal crisis and severe shock in selected patients. It helps reduce inflammation and provides corticosteroid activity when required.
Yes, Betnesam Injection may be used as part of the treatment of status asthmaticus, a severe and potentially life-threatening asthma attack. It helps reduce inflammation in the airways but does not provide immediate relief from breathing difficulties. Other emergency medicines and supportive treatments are required, and the injection must not replace them.
Betnesam Injection may be used in the management of severe allergic reactions, including certain drug-related reactions. It helps reduce inflammation and the body's excessive inflammatory response. However, in anaphylaxis, adrenaline is the first-line treatment, and Betnesam Injection must not replace or delay emergency treatment.
Adrenal crisis occurs when the body has insufficient corticosteroid hormones to cope with physical stress. Betnesam Injection provides corticosteroid activity that may help compensate for this deficiency in certain circumstances.
Betnesam Injection may be used locally to treat certain soft tissue inflammatory conditions, such as tennis elbow, tenosynovitis, and bursitis. It helps reduce inflammation, swelling, and discomfort in the affected area.
Yes, Betnesam Injection may increase blood sugar levels, especially in people who have diabetes. Your doctor may recommend closer blood sugar monitoring during treatment. Inform your doctor if you have diabetes or take medicines to control blood sugar, as your treatment may need adjustment.
Yes, Betnesam Injection can suppress immune responses and make it harder for the body to fight infections. It may also mask some of the usual signs of infection, making them harder to recognise. Tell your doctor if you develop infection symptoms.
Yes, Betnesam Injection can sometimes cause mood changes, anxiety, irritability, or difficulty sleeping. In rare cases, more serious mental health problems may occur, particularly with higher doses. Inform your doctor immediately if you notice unusual changes in mood, behaviour, or thinking.
You should not stop a prescribed course of Betnesam Injection without consulting your doctor, particularly after prolonged treatment. Corticosteroids can suppress the body’s natural production of hormones, and sudden withdrawal may cause symptoms such as weakness, dizziness, and low blood pressure. Your doctor will decide whether the dose needs to be reduced gradually before stopping treatment.

Fact Box

Chemical Class

21- hydroxysteroids

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Glucocorticoids

References

  1. Boushey HA. Drugs Used in Asthma. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 348.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 125-26.
  3. Central Drugs Standard Control Organisation (CDSCO): Betamethasone. [Accessed 03 Apr. 2019] (online) Available from:
  4. Betamethasone sodium phosphate [FDA Label]. Kenilworth, NJ: Schering Corporation; 2008. [Accessed 07 Feb. 2025] (online) Available from:
  5. Betamethasone sodium phosphate [Product Information]. Mumbai, Maharashtra: GlaxoSmithKline Pharmaceuticals Limited; 2025. [Accessed 21 Mar. 2025] (online) Available from:
  6. Betamethasone [patient Information Leaflet]. Stockholm, Sweden: RPH Pharmaceuticals AB; 2025. [Accessed 04 Nov. 2026] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biosam Life Science Private Limited
Address: G-9, 222, KARADVA ROAD, DINDOLI, SURAT, GUJARAT, PIN- 394210, INDIA, MOB- 9470216982, 9504896445

Vendor Details

Country of origin: India
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