Baraclude 0.5mg Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Baraclude 0.5mg Tablet is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Baraclude 0.5mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.

Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.

Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Benefits of Baraclude Tablet

In Chronic hepatitis B virus (HBV) infection

In patients with chronic hepatitis B virus (HBV) infection, Baraclude 0.5mg Tablet works by preventing the HBV virus from multiplying in the body. It helps control the infection and makes the immune system work better. This lowers the chances of getting complications and improves the quality of life.

This medicine is always taken in combination with other antiretroviral medicines. It is not a cure and should neither be used to prevent HBV infection. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of the medicine.

In HIV infection

Baraclude 0.5mg Tablet works by preventing the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. This medicine is always taken in combination with other antiretroviral medicines.

It is not a cure for HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take Baraclude 0.5mg Tablet as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.

Side effects of Baraclude Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Baraclude

  • Headache
  • Nausea
  • Rash
  • Vomiting
  • Fatigue
  • Stomach pain
  • Diarrhea

How to use Baraclude Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Baraclude 0.5mg Tablet is to be taken empty stomach.

How Baraclude Tablet works

Baraclude 0.5mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Baraclude 0.5mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Baraclude 0.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Baraclude 0.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Baraclude 0.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Baraclude 0.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Baraclude 0.5mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Baraclude 0.5mg Tablet is safe to use in patients with liver disease. No dose adjustment of Baraclude 0.5mg Tablet is recommended.

What if you forget to take Baraclude Tablet?

If you miss a dose of Baraclude 0.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Baraclude 0.5mg Tablet
₹74.55/Tablet
Entehep 0.5 Tablet
Zydus Cadila
₹76.96/Tablet
3% costlier
Anticanol 0.5 Tablet
Knoll Pharmaceuticals Ltd
₹80/Tablet
7% costlier
Entehep 0.5 Tablet
Zydus Cadila
₹81.73/Tablet
10% costlier
Entaliv 0.5 Tablet
Dr Reddy's Laboratories Ltd
₹81.98/Tablet
10% costlier
₹81.98/Tablet
10% costlier

Quick Tips

  • You have been prescribed Baraclude 0.5mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
  • Take it on an empty stomach, at least 2 hours after or before a meal.
  • Baraclude 0.5mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Fact Box

Chemical Class
Nucleoside analog
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Interaction with Drugs

Taking Baraclude with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Alovir, Acvirax, Oveer
LIFE-THREATENING
Brand(s): Urinol, Zeric, Seloric
LIFE-THREATENING
Brand(s): Herpinil-F, Famtag, Virax FC
LIFE-THREATENING
Brand(s): Ganpyar
LIFE-THREATENING

Patient Concerns

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I have HBV related chronic liver problem .Local urologist suggest me to take rapilif d 8 for urine block problem?Can i take that medicine with entavir for hepatitis b virus and cronic liver disease?
Dr. Praveen Pushkar
Urology
Yes u can take it
Suffering from Hepatitis B virus from last one week. Please suggest me.
Dr. Anshum Aneja Arora
Pulmonology
Pls consult a gastroenterologist
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Do you have any questions related to Baraclude 0.5mg Tablet ?

User Feedback


FAQs

Q. How should Baraclude 0.5mg Tablet be taken?

You should take Baraclude 0.5mg Tablet exactly as prescribed by your doctor and continue taking it till your doctor tells you to stop. It is usually taken once a day on an empty stomach, at least 2 hours after a meal and at least 2 hours before the next meal. It is advised to take it around the same time every day. If not sure, consult your doctor.

Q. Can Baraclude 0.5mg Tablet cause liver problems?

Yes, Baraclude 0.5mg Tablet can cause serious liver problems like hepatomegaly (enlargement of the liver) and steatosis (an increased build-up of fat in the liver). It is important to know that hepatomegaly along with steatosis is a serious medical emergency which requires immediate medical attention.

Q. What are the symptoms of serious liver problems?

The symptoms of liver problems include jaundice (a condition in which your skin or the white part of your eyes turns yellow), dark-colored urine, light-colored stools, loss of appetite, nausea and stomach pain. These symptoms are more common in women, overweight patients, or if you have been on Baraclude 0.5mg Tablet for a long time. Immediately contact your doctor if you experience any such symptoms.

Q. What is drug resistance? Can I develop drug resistance with Baraclude 0.5mg Tablet?

Drug resistance is a state where the medicine which was once effective in treating an infection becomes ineffective. This mainly happens due to the ability acquired by the virus or bacteria to get modified inside the body which affects the overall working of the medicine. Hence, the medicine is no longer able to fight against the virus or bacteria. Generally, drug resistance with Baraclude 0.5mg Tablet is more likely to happen if you take less dose than what is recommended.

Q. How long should I take Baraclude 0.5mg Tablet?

Do not stop taking entecavir without consulting your doctor. Stopping entecavir before treatment may worsen your hepatitis. This can happen during the first several months after you stop taking entecavir. Take the medicine strictly as advised and do not miss any dose.

Q. What if HIV infection co-exists with HBV infection? Will this affect treatment with Baraclude 0.5mg Tablet?

The use of Baraclude 0.5mg Tablet is not recommended in HBV patients who are also diagnosed with HIV, until and unless these patients start taking medicines for HIV management. Starting Baraclude 0.5mg Tablet in such patients may cause resistance to the prescribed HIV medicines. Therefore, doctors recommend tests for HIV in patients diagnosed with HBV infection before starting treatment with Baraclude 0.5mg Tablet.

Q. Can Baraclude 0.5mg Tablet cure hepatitis B?

No, Baraclude 0.5mg Tablet does not cure hepatitis B but may improve the condition of the liver. The medicine may help decrease the amount of hepatitis B virus (HBV) present in the body. This is done by limiting the ability of HBV to multiply and further infect new liver cells.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1616-617.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 869.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 474-75.
  4. Entecavir. Uxbridge, Middlesex: Bristol-Myers Squibb Pharmaceuticals limited; 2006 [revised 1 Feb. 2019] (online) Available from:External Link
  5. Entecavir. Princeton, New Jersey: Bristol-Myers Squibb; 2005 [revised Oct. 2012]. [Accessed 31 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Bristol-Myers Squibb India Pvt. Ltd., The India Bulls Finance Centre, 6th Floor, Tower 1, Senapati Bapat Marg, Elphinstone (W), Mumbai - 400013
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We do not facilitate sale of this product at present

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