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Last updated on:
27 Sep 2019 | 11:33 AM (IST)
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Aviglen MF Tablet


Overview

Introduction

Aviglen MF Tablet is used in the treatment of type 2 diabetes mellitus. It is a combination medicine that can control blood sugar better than a single medication.

Aviglen MF Tablet should be used along with proper diet and regular exercise for best results. Monitor your blood sugar level regularly while taking this medicine as it may cause hypoglycemia (low blood sugar level).

Uses of Aviglen MF Tablet

Aviglen MF Tablet side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Aviglen MF Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aviglen MF Tablet is to be taken with food.
This medicine may cause stomach upset if taken empty stomach.

How Aviglen MF Tablet works

Aviglen MF Tablet is a combination of two antidiabetic medicines: Glibenclamide and Metformin. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Aviglen MF Tablet related warnings

Alcohol
UNSAFE
It is unsafe to consume alcohol with Aviglen MF Tablet Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
SAFE IF PRESCRIBED
Aviglen MF Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Lactation
SAFE IF PRESCRIBED
Aviglen MF Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
UNSAFE
Aviglen MF Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver
CAUTION
Aviglen MF Tablet should be used with caution in patients with liver disease. Dose adjustment of Aviglen MF Tablet may be needed. Please consult your doctor.
Aviglen MF Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Aviglen MF Tablet
₹2.75/Tablet
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Expert Advice

  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Aviglen MF Tablet.
  • Take it with food to lower your chance of having an upset stomach.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Aviglen MF Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to Aviglen MF

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I have type-2 Diabetes taking trivolib1 And glisen mf 1 Two times a day.before meal.but.my sugar not controlled my.fbs sugar-236 And pp2bs.is 356 Pl,advisr what to do
Dr. Ila Jain Khandelwal
Pathologist
Hi I suggest you should consult your diabetologist or general practitinoer He will see all your previous records and review your treatment
Since 3 years I have Type 2 Diabetes and am presently on 1 tab. of glynase MF .My fasting is 130 and PP goes up to 170-180. I want to lower it further. I have been advised to take 1 tab. of voglibose 0.3 with lunch.Iam unable to walk more than 1 k.m. due to osteoarthritis but I am cycling daily for one hour to compensate. What do I do to control B-G level more effectively?
Dr. Sanjay Bhatt
Diabetes Specialist
It is ok but further maintain your calories intake as per your BMI.CONSULT DIABETIC EDUCATOR
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Do you have any questions related to Aviglen MF Tablet?

User Feedback


FAQs

Q. What is Aviglen MF?

Aviglen MF is a combination of two medicines: Glibenclamide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glibenclamide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

Q. What is type 2 diabetes?

Type 2 diabetes is the most common form of diabetes. It is a condition in which the body is unable to make enough insulin, and the insulin produced by the body does not work well. When this happens, the glucose level in the blood rises and leads to serious medical problems. Symptoms of high blood sugar include frequent urination, increased thirst and increased hunger. Diabetes, if not treated properly, can cause long-term complications like neuropathy (nerve damage), nephropathy (kidney damage), eye damage (retinopathy), foot problems and also a higher risk of developing heart diseases.

Q. What are the possible side effects of Aviglen MF?

The use of Aviglen MF is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Q. Can the use of Aviglen MF cause hypoglycemia?

Yes, the use of Aviglen MF can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. So, regular monitoring of blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Can the use of Aviglen MF lead to Vitamin B12 deficiency?

Yes, the use of Aviglen MF can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient may feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Aviglen MF should not to be taken?

The use of Aviglen MF should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Aviglen MF?

No, it is not safe to take Aviglen MF along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Aviglen MF?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glyburide and Metformin HCl. Princeton, New Jersey: Bristol-Myers Squibb Company; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Glibenclamide and metformin. [Accessed 08 Apr. 2019] (online) Available from:External Link
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