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Aveva Combipack Injection

Fulvestrant (250mg/5ml)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C
Aveva Combipack Injection is an estrogen blocker. It is used in the treatment of breast cancer in women who have gone through menopause. It works by adjusting the level of estrogen and slow down the growth of cancer cells.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 26 Nov 2025 | 01:00 AM (IST)
₹11097 MRP ₹12182.819% off 
 
 
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General Information

Contains

Fulvestrant (250mg/5ml)

Marketer

Zydus Cadila

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Aveva Combipack Injection image
Aveva Combipack Injection image

Product introduction

Aveva Combipack Injection is given as an injection into the muscles under the supervision of a doctor. It should be taken as doctor your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include injection site reaction, headache, vomiting, allergic reaction, and nausea. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, tell your doctor if you ever had kidney or liver disease or had bleeding disorder or had any blood clotting medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Aveva Injection

Benefits of Aveva Injection

Breast cancer
Breast cancer happens when cells in the breast grow abnormally and form tumors that can spread to other parts of the body. This often occurs due to hormone-driven growth, especially in cancers that depend on estrogen. Aveva Combipack Injection works by blocking the effect of estrogen on these cancer cells and reducing their ability to multiply. This helps slow down or stop tumor growth, relieve symptoms, and improve treatment outcomes in people with breast cancer.

Side effects of Aveva Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aveva
  • Nausea
  • Vomiting
  • Back pain
  • Fatigue
  • Hot flashes
  • Decreased appetite
  • Constipation
  • Bone pain
  • Joint pain
  • Cough
  • Injection site pain
  • Headache
  • Pain in extremity
  • Musculoskeletal (bone, muscle or joint) pain
  • Breathlessness
  • Increased alanine aminotransferase
  • Increased aspartate aminotransferase
  • Weakness

How to use Aveva Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Aveva Injection works

Aveva Combipack Injection blocks the action of estrogen on breast cancer cells. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.

All substitutes for Aveva Combipack Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Aveva Combipack Injection is used for the treatment of hormone dependent breast cancer.
  • It should only be taken by women who have undergone menopause and cannot become pregnant.
  • It is given as a slow injection into the muscles (intramuscular) of your buttock.
  • Inform your doctor if you have any bleeding disorder, kidney or liver disease or if you are receiving any medicines to prevent blood clots.
  • Do not take Aveva Combipack Injection if you are pregnant or breastfeeding.
  • Aveva Combipack Injection is used for the treatment of hormone dependent breast cancer.
  • It should only be taken by women who have undergone menopause and cannot become pregnant.
  • It is given as a slow injection into the muscles (intramuscular) of your buttock.
  • Inform your doctor if you have any bleeding disorder, kidney or liver disease or if you are receiving any medicines to prevent blood clots.
  • Do not take Aveva Combipack Injection if you are pregnant or breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Aveva Combipack Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Aveva Combipack Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Aveva Combipack Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Aveva Combipack Injection does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Aveva Combipack Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Limited information is available on the use of Aveva Combipack Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver

Liver

CAUTION
Aveva Combipack Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Aveva with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Conjugated Estrogens (Vaginal Route)

Avoid concurrent use.
Severe

Conjugated Estrogens (Oral Route)

Do not consume Fulvestrant with Conjugated Estrogens if you have or had breast cancer. If essential, consult your doctor. Conjugated Estrogens may reduce the efficacy of Fulvestrant.
Severe

Dehydroepiandrosterone (Micronized) (Oral Route)

Do not consume Fulvestrant with Dehydroepiandrosterone (Micronized) if you have or had breast cancer. If essential, consult your doctor. Dehydroepiandrosterone (Micronized) may reduce the efficacy of Fulvestrant.
Severe

Estradiol (Oral Route)

Do not consume Fulvestrant with Estradiol if you have or had breast cancer. If essential, consult your doctor. Estradiol may reduce the efficacy of Fulvestrant.
Severe

Estradiol (Injection Route)

Do not consume Fulvestrant with Estradiol if you have or had breast cancer. If essential, consult your doctor. Estradiol may reduce the efficacy of Fulvestrant.

Frequently asked questions

Aveva Combipack Injection contains a medicine, Fulvestrant which is used to treat breast cancer in women who have gone through menopause.
Your doctor would advise you the exact dose of this medicine. It is given as a slow (1 to 2 minutes) intramuscular (deep into the muscle) injection in your buttocks. It is administered by a medical healthcare professional only.
The common side effects associated with this medicine are headache, vomiting, urinary tract infection, diarrhea, vaginal bleeding, low platelets count and back pain. If any of these side effects bother you, consult with your doctor.
Aveva Combipack Injection is a medicine, which is used to treat breast cancer in women who have gone through menopause.
Your doctor would advise you the exact dose of this medicine. It is given as a slow (1 to 2 minutes) intramuscular (deep into the muscle) injection into your buttocks. It is administered by a medical healthcare professional only.
The common side effects associated with this medicine are headache, vomiting, urinary tract infection, diarrhea, vaginal bleeding, low platelets count and back pain. If any of these side effects bother you, consult with your doctor.

Fact Box

Chemical Class

Estrogen derivative

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Estrogen Receptor Antagonists

References

  1. Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
  2. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1759-60.
  3. Fulvestrant. Luton, Bedfordshire: AstraZeneca UK Limited; 2004 [revised 6 Sep 2018]. [Accessed 03 Apr. 2019] (online) Available from:
  4. Fulvestrant. Cheshire, England: AstraZeneca UK Limited; 2002 [revised Jul. 2011]. [Accessed 03 Apr. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
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