Medicine Overview of Ascend Tablet
Side effects of Ascend Tablet
Nausea, Abdominal pain, Constipation, Diarrhoea, Flatulence.
How to use Ascend Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Ascend 20mg Tablet at a fixed time.
How Ascend Tablet works
Ascend 20mg tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid-related indigestion and heartburn.
In Depth Information on Ascend Tablet
Expert advice for Ascend Tablet
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Ascend can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine.
- Inform your doctor if you are suffering from osteoporosis as Ascend can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate.
- Ascend is a well-tolerated medicine and provides relief for a long time.
- It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them.
- Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor
Special precautions for Ascend 20mg Tablet
Taking a large amount of alcohol can increase acidity and ca+more
use acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition....
WEIGH RISKS VS BENEFITS
Ascend 20mg Tablet may be unsafe to use during pregnancy.+more
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor....
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Ascend 20mg Tablet is probably usafe to use during lactation+more
. Limited human data suggests that the drug could represent a significant risk to the baby....
Ascend 20mg Tablet may make you feel dizzy, sleepy, tired, o+more
r decrease alertness. If this happens, do not drive....
Ascend 20mg Tablet is safe to use in patients with kidney di+more
sease. No dose adjustment of Ascend 20mg Tablet is recommended....
Ascend 20mg Tablet should be used with caution in patients w+more
ith severe liver disease. Dose adjustment of Ascend 20mg Tablet may be needed. Please consult your doctor....
Severely interacts with other drugs like
Mezolam 7.5mg Injection, Azivent 500mg Tablet, Zathrin Redimix Suspension, Pratham 200mg/5ml Suspension
If you miss a dose of Rabeprazole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions for Ascend 20mg Tablet
Frequently asked questions for Rabeprazole
No, Ascend is not an over the counter product, it is available when prescribed by a doctor.
Ascend is not an antacid. It belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.
Yes, long term use of Ascend can cause osteoporosis (thinning of bones). It decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of hip, wrist or spine. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.
Ascend can be taken with antacids like aluminum hydroxide, magnesium carbonate or sodium bicarbonate. Ascend takes a few days to show its effect, so antacids can be taken during that time for relief of acidity and heartburn. However, antacids should be taken two hours before or one hour after taking Ascend as antacids can increase the pH of the stomach and decrease the action of Ascend which requires a lower pH for its action.
No, Ascend has no addictive potential. It shows no withdrawal symptoms when you stop using this medicine.
Yes, Ascend is safe if taken for prescribed duration in prescribed doses as advised by your doctor. However, there are some very common side effects that you can experience at effective doses like nausea, abdominal pain, constipation, diarrhea, and flatulence.
No, hair loss has not been reported as a side effect of Ascend. Talk to your doctor in case there is excessive hair fall as it could be due to some underlying problem that needs attention.
Flatulence (gas) has been reported as a common side effect of Ascend. Although it would be mild to moderate in nature and transient.
Tinnitus (ringing sensation in the ears) has not been seen as a side effect with the use of Ascend. Talk to your doctor in case you have this problem as it could be due to some underlying condition that needs attention.
Weight gain has been reported as a rare side effect of Ascend. Weight gain can add to your problem of acidity and heartburn. So, you must try to do some exercise and make healthy changes in your diet to control your weight.
Yes, like any other medicine, Ascend also expires. Always check the expiry date on the pack of the medicine before using it.
Constipation is a common side effect seen in patients using Ascend. Making healthy lifestyle changes like doing yoga, taking high fiber diet and plenty of fluids will prevent constipation.
Ascend is not reported to cause high blood pressure. In case you experience high blood pressure, talk to your doctor as it may need attention. Common side effects seen with Ascend includes nausea, abdominal pain, constipation, diarrhea, and flatulence.
Headache is reported as one of the common side effects of Ascend. Please consult your doctor in case you experience an intolerable headache for a prolonged duration while taking Ascend.
Q. Can I take Ascend with ranitidine?
Yes, Ascend can be taken with ranitidine. As Ascend show its effect after some days, Ranitidine can be taken for immediate relief. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.
Q. Can I take Ascend with ibuprofen?
Ascend can be taken with ibuprofen. Ascend is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. Can I take Ascend with paracetamol?
Ascend can be taken with paracetamol. Ascend is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. How is Ascend metabolized?
Ascend is metabolized in the liver mainly by microsomal CYP450 enzymes (CYP2C19 and CYP3A4). Patients with poor CYP2C19 enzymatic activity will have higher levels of Ascend for a long time and a better suppression of stomach acid.
No, Ascend is not meant for throat infections. However, it may be given along with antibiotics and other drugs to protect the stomach from excessive acid secretion.
Q. Why is Ascend used with cinitapride for some conditions?
Cinitapride increases the movement of the gut and is useful in the treatment of conditions like heartburn, dyspepsia and is also useful in the treatment of reflux esophagitis. It has much better efficacy when it is used with Ascend.
Ascend does not have any role in the treatment of ulcerative colitis. However, it can be given if there is associated dyspepsia or increased stomach acid secretion. Talk to your doctor before taking any treatment for ulcerative colitis.
Yes, Ascend is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Ascend decreases the production of acid in the stomach and can help in healing the inflamed and eroded esophagus.The efficacy is better when it is given in combination with a prokinetic agent like domperidone.
No, Ascend is not used for the treatment of weight loss. It is a proton pump inhibitor and is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.
A hiatus hernia is the bulging of the stomach into the chest through an esophageal opening in the diaphragm which is larger than the normal size. A hiatus hernia is associated with acidity and heartburn. Ascend does not play any role in treating hiatus hernia, however, it can help in relieving the symptoms of acidity, heartburn and acid reflux.
Q. Is Ascend better than omeprazole?
Ascend and omeprazole belong to the same class of medicines known as proton pump inhibitors (PPIs) and work in the same way to decrease acid production in the stomach. However, few clinical studies have shown that Ascend provides better relief of the symptoms including the daytime pain of duodenal ulcers. The difference in response may also vary in different patients.
Q. Is Ascend better than pantoprazole?
Ascend and pantoprazole belong to the same class of medicines known as proton pump inhibitors (PPIs) and work in the same way to decrease acid production in the stomach. However, few clinical studies have shown that Ascend is more effective in decreasing acid secretion compared to pantoprazole. The difference in response may also vary in different patients.
Yes, vitamin D can be taken with Ascend. Vitamin D is generally advised to be taken as a supplement with Ascend as its long-term use decreases the absorption of calcium and cause calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist and spine fractures.
Q. How is Ascend different from esomeprazole?
Ascend and esomeprazole both belong to the same class of drugs and are used in disease conditions with excess acid production like heartburn, acidity, stomach ulcers and intestinal ulcers. Both decrease acid production in the stomach and are seen to be almost equally effective and safe in many clinical research studies. However, the response may vary from patient to patient and depend on the dose.
Ascend is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in the symptomatic relief by decreasing associated acidity, reflux, and heartburn.
Q. How is Ascend different from ranitidine?
Both Ascend and ranitidine lower the amount of acid produced in the stomach. Ascend is seen to be more effective in resolving heartburn in patients with gastroesophageal reflux disease (GERD). It rapidly heals stomach and duodenal ulcers and also prevents ulcers formation in patients who use nonsteroidal anti-inflammatory drugs (NSAIDs). However, the effect of these medicines may vary from patient to patient.
Q. Can I take Ascend with domperidone?
Ascend can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
Long-term use of Ascend can lower magnesium levels in patients taking multiple daily doses for a year or longer (at least 3 months). Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures, dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches or spasm of the voice box.
Substitutes for Ascend Tablet
Renvorab 20 Tablet
Leeford Healthcare Ltd
Rabopep 20mg Tablet
Seagull Pharmaceutical Pvt Ltd
Cyra 20mg Tablet
Systopic Laboratories Pvt Ltd
Themis Medicare Ltd
Rabekind 20mg Tablet
Mankind Pharma Ltd