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MDS (Oral Pathology & Microbiology), BDS
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MD (Pharmacology), MBBS
Last updated on:
14 May 2019 | 05:16 PM (IST)
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Amaryl M Forte 2mg Tablet PR


Overview

Introduction

Amaryl M Forte 2mg Tablet PR is a medicine used in the treatment of type 2 diabetes. It is a combination of two medicines that effectively control blood sugar levels, when a single medication is not effective. It should be used along with a proper diet and regular exercise for best results. It should be taken with food to avoid the side effects like nausea and upset stomach.

Uses of Amaryl M Forte Tablet PR

Amaryl M Forte Tablet PR side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Amaryl M Forte Tablet PR

Use it as advised by your doctor or check the label for directions before use. Amaryl M Forte 2mg Tablet PR is to be taken with food.
Amaryl M Forte 2mg Tablet PR may cause stomach upset if taken empty stomach.

How Amaryl M Forte Tablet PR works

Amaryl M Forte 2mg Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Amaryl M Forte Tablet PR related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Amaryl M Forte 2mg Tablet PR. Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
WEIGH RISKS VS BENEFITS
Amaryl M Forte 2mg Tablet PR may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Amaryl M Forte 2mg Tablet PR is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Amaryl M Forte 2mg Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Amaryl M Forte 2mg Tablet PR may be needed. Please consult your doctor.
Use of Amaryl M Forte 2mg Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Amaryl M Forte 2mg Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Amaryl M Forte 2mg Tablet PR may be needed. Please consult your doctor.
Amaryl M Forte 2mg Tablet PR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Expert Advice

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Amaryl M Forte 2mg Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to Amaryl M Forte

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I am talking amaryl forte 1mg morning Janumet 50 in evening. .can I take one brand to control my type 2 Diabetes.With these medicine sugar level remains below 125 bot h FBS and random.
Dr. Jagruti Shah
Diabetes Specialist
It is always advisable to do both BSF/PP OR post dinner to know sugars are contoled or not with may be 4 monthly HbA1C. If both values are in acceptable in controled range that is HBa1c lessthan 7 and BSF/PP between 100-140 and S. creat normal then it is advisable to continue same medicine and not change brands . Using two different group of medicines are more often to patients advantage.
I am suffering from type 2 diabetes my current sugar level BSF 166 and PP 225 currently i take amryl m forte 1 tablet once daily
Dr. Sanjay Bhatt
Diabetes Specialist
It is not good control.A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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User Feedback


FAQs

Q. What are the recommended storage conditions for Amaryl M Forte?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Amaryl M Forte lead to lactic acidosis?

Yes, the use of Amaryl M Forte can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Amaryl M Forte and consult your doctor immediately.

Q. What is Amaryl M Forte?

Amaryl M Forte is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Amaryl M Forte?

The use of Amaryl M Forte is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Can the use of Amaryl M Forte lead to Vitamin B12 deficiency?

Yes, the use of Amaryl M Forte can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Can the use of Amaryl M Forte cause hypoglycemia?

Yes, the use of Amaryl M Forte can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Is it safe to take alcohol while I am also taking Amaryl M Forte?

No, it is not safe to take Amaryl M Forte along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glimepiride + Metformin. Karachi, Pakistan: Sanofi-Aventis Pakistan Ltd. [Accessed 23 Jan. 2019] (online) Available from:External Link
  2. Metformin Hydrochloride Prolonged Release & Glimepiride Tablets I.P. Ankleshwar: Sanofi India Limited; 2018. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
A licensed pharmacy from your nearest location will deliver Amaryl M Forte 2mg Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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