Agotrig Injection
Prescription RequiredProduct introduction
Agotrig Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of uterus grows excessively and causes symptoms like pain, heavy or irregular periods), and central precocious puberty (very early puberty).
Agotrig Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Hot flashes, weakness, increased sweating, fatigue, back pain, and erectile dysfunction are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Agotrig Injection
- Prostate cancer
- Endometriosis
- Precocious puberty (premature puberty)
Benefits of Agotrig Injection
In Prostate cancer
Prostate cancer is a condition where cells in the prostate gland grow uncontrollably. Agotrig Injection helps by lowering certain hormones in the body that fuel the growth of prostate cancer cells. This slows disease progression and helps relieve related symptoms.
In Endometriosis
Endometriosis is a condition where tissue similar to the lining of the uterus grows outside it, causing pain and irregular periods. Agotrig Injection reduces hormone levels that trigger this growth, helping to lessen pain, bleeding, and other discomforts.
In Precocious puberty (premature puberty)
Precocious puberty is when children show signs of puberty earlier than normal. Agotrig Injection works by controlling the release of hormones responsible for early puberty, helping to delay development until the appropriate age and supporting healthy growth.
Side effects of Agotrig Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Agotrig
- Weakness
- Increased sweating
- Back pain
- Paresthesia (tingling or pricking sensation)
- Hot flashes
- Erectile dysfunction
How to use Agotrig Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Agotrig Injection works
Agotrig Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Agotrig Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Agotrig Injection. Please consult your doctor.
Pregnancy
UNSAFE
Agotrig Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Agotrig Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Agotrig Injection may cause side effects which could affect your ability to drive.
You may feel dizzy, tired or have problems with your eyesight such as blurred vision. This may affect your driving ability.
You may feel dizzy, tired or have problems with your eyesight such as blurred vision. This may affect your driving ability.
Kidney
CAUTION
Agotrig Injection should be used with caution in patients with kidney disease. Dose adjustment of Agotrig Injection may be needed. Please consult your doctor.
Liver
CAUTION
Agotrig Injection should be used with caution in patients with liver disease. Dose adjustment of Agotrig Injection may be needed. Please consult your doctor.
What if you forget to take Agotrig Injection?
If you miss a dose of Agotrig Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Agotrig Injection helps in the treatment of locally advanced or metastatic prostate cancer.
- It is given as an injection either under the skin or into a muscle.
- It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
- It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
- Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
- Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
- It may also be used to treat endometriosis and precocious puberty (premature puberty).
Fact Box
Chemical Class
Polypeptides
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Gonadotropin-releasing hormone (GnRH) Agonists
Interaction with drugs
Taking Agotrig with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Triptorelin with Domperidone.
Concomitant use may affect heart rhythm and can be fatal.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their p
Patient concerns
FAQs
What is Agotrig Injection used for?
Agotrig Injection is used to treat prostate cancer. It is also used to treat central precocious puberty (CPP) in children aged 2 years and older, and helps delay early puberty by controlling hormone levels.
Are there any serious side effects of using Agotrig Injection?
Yes, serious side effects of Agotrig Injection may include emotional changes like irritability or aggression, convulsions (seizures), or increased pressure in the brain, which may cause headache, blurred vision, or nausea. If any of these occur, medical attention is necessary.
Can Agotrig Injection cause puberty symptoms to worsen at first?
Yes, during the first 2 to 4 weeks after starting Agotrig Injection treatment, children may temporarily show more signs of puberty. This is normal and happens because the hormone levels rise briefly before decreasing.
Who should not receive Agotrig Injection?
Agotrig Injection should not be used in people with known allergies to it or similar medications. It is also not for use in pregnant individuals or those with certain types of hormone-sensitive conditions without a doctor's supervision.
How is the response to Agotrig Injection monitored during treatment?
Doctors check hormone levels in the blood and track the child’s growth and bone development regularly to make sure Agotrig Injection is working properly and safely.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1410-11.
- Triptorelin pamoate. Slough, Berkshire: Ipsen Ltd.; 2010 [revised 17 Dec. 2016]. [Accessed 23 Jan. 2019] (online) Avaialble from:
- Triptorelin pamoate. Martigny, Switzerland: Debio RP; 2000 [Accessed Jul. 2014]. [Accessed 27 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Country of origin: India
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