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14 May 2019 | 11:54 AM (IST)
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Afoglip M 500 Tablet ER


Overview

Introduction

Afoglip M 500 Tablet ER is a medicine used in the treatment of type 2 diabetes mellitus. It provides better control of blood sugar when single therapy is not effective and reduces both fasting and postmeal sugar levels. It should be used along with a proper diet and exercise for maximum effect. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level) as a side effect.

Uses of Afoglip M Tablet ER

Afoglip M Tablet ER side effects

Common
  • Diarrhea
  • Nausea
  • Vomiting
  • Stomach upset
  • Headache
  • Nasal congestion
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Afoglip M Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afoglip M 500 Tablet ER is to be taken with food.
Afoglip M 500 Tablet ER may cause stomach upset if taken on empty stomach.

How Afoglip M Tablet ER works

Afoglip M 500 Tablet ER is a combination of two antidiabetic medicines: Metformin and Teneligliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Afoglip M Tablet ER related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Afoglip M 500 Tablet ER. Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
Unknown. Human and animal studies are not available. Please consult your doctor.
Lactation
No information is available on the use of Afoglip M 500 Tablet ER during lactation. Please consult your doctor.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Afoglip M 500 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Afoglip M 500 Tablet ER may be needed. Please consult your doctor.
Use of Afoglip M 500 Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Afoglip M 500 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Afoglip M 500 Tablet ER may be needed. Please consult your doctor.
Afoglip M 500 Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Afoglip M 500 Tablet ER
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Eternex-M 500 Tablet ER
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₹14.03/Tablet ER
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Tenepure-M 500 Tablet ER
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₹12.86/Tablet ER
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Megagliptin MF Tablet ER
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Glytrin-Met Tablet ER
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Expert Advice

  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Afoglip M 500 Tablet ER may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Patient Concerns

Questions Related to Afoglip M

arrow
Hi Doctor I have Type 2 diabetes, at present i m taking istamet 50/1000 mg, kindly advise if my medicine can be stopped
Dr. Shikha Mishra
Dietician
Please consult doctor regarding this issue
FOR TYPE 2 DIABETES, WHICH IS THE BEST COMBINATION IN TRIVOGLITOR, TENEZA-M AND TRICLAZONE, WITH 500 MG METFORMIN, IN VIEW OF LEAST SIDE EFFECTS, BEST EFFECTIVENESS AND QUALITY OF SALTS ???
Dr. Ashwin Porwal
Diabetes Specialist
they all are differentit varies from person to person
arrow
Do you have any questions related to Afoglip M 500 Tablet ER?

User Feedback


FAQs

Q. What are the instructions for the storage and disposal of Afoglip M?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Afoglip M?

Afoglip M is a combination of two medicines: Metformin and Teneligliptin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Teneligliptin inhibits the enzyme DP4 inhibitor and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.

Q. What are the possible side effects of Afoglip M?

The use of Afoglip M is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious, but rare side effect like lactic acidosis. On long-term use it can also lead to vitamin B12 deficiency.

Q. Are there any specific conditions in which Afoglip M should not be taken?

The use of Afoglip M should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Afoglip M?

No, it is not safe to take Afoglip M along with alcohol. It can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or hepatic impairment.

Q. Can the use of Afoglip M cause hypoglycemia?

The use of Afoglip M does not usually cause hypoglycemia (low blood sugar level). However, hypoglycemia may occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry glucose tablets, honey or fruit juice with you.

Q. Can the use of Afoglip M lead to Vitamin B12 deficiency?

Yes, the use of Afoglip M can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
A licensed pharmacy from your nearest location will deliver Afoglip M 500 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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