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Adelphane Esidrex Tablet

Prescription Required

Product introduction

Adelphane Esidrex Tablet is used to treat hypertension (high blood pressure). It is a combination of medicines that helps to control blood pressure when a single medication is not effective. It lowers blood pressure and reduces the risk of future heart attack and stroke.

Adelphane Esidrex Tablet should be taken with or without food preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

Nausea, loss of appetite, headache are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or Do not go away. It is advised to avoid getting overheated in hot weather or during exercise, as it may lead to dehydration and make you feel dizzy. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth and extreme thirst. Dizziness or headache may occur due to low blood pressure, hence rise slowly from sitting position or avoid driving.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, level of electrolytes, and blood sugar level checked regularly to make sure that this medicine is working properly.

Uses of Adelphane Esidrex Tablet

Benefits of Adelphane Esidrex Tablet

In Hypertension (high blood pressure)

Adelphane Esidrex Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Adelphane Esidrex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Adelphane Esidrex

  • Nausea
  • Loss of appetite
  • Headache
  • Drowsiness
  • Decreased potassium level in blood
  • Increased blood lipid level
  • Increased uric acid level in blood
  • Sweating
  • Dizziness
  • Palpitations
  • Increased heart rate
  • Flushing of skin
  • Glucose intolerance
  • Electrolyte imbalance

How to use Adelphane Esidrex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Adelphane Esidrex Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Adelphane Esidrex Tablet works

Adelphane Esidrex Tablet is a combination of three medicines: Reserpine, Dihydralazine and Hydrochlorothiazide which lower blood pressure effectively. Reserpine is a biogenic amine depletor and Dihydralazine is a potassium channel opener. They work by relaxing blood vessels which allows more blood and oxygen to reach the heart and other organs. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Adelphane Esidrex Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Adelphane Esidrex Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Adelphane Esidrex Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Adelphane Esidrex Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Adelphane Esidrex Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Adelphane Esidrex Tablet may be needed. Please consult your doctor.
Use of Adelphane Esidrex Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Adelphane Esidrex Tablet should be used with caution in patients with liver disease. Dose adjustment of Adelphane Esidrex Tablet may be needed. Please consult your doctor.

What if you forget to take Adelphane Esidrex Tablet?

If you miss a dose of Adelphane Esidrex Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Adelphane Esidrex Tablet is prescribed to reduce high blood pressure and the risk of future heart attack and stroke.
  • It helps you to lose water via urination. If, however, you lose too much fluid, you may become dehydrated. This will make you feel thirsty and make your skin look and feel dry. Consult your doctor immediately.
  • Monitor your blood pressure regularly after starting treatment with Adelphane Esidrex Tablet, and notify your doctor if it does not lower down or if it becomes too low.
  • Your doctor may get regular tests done to monitor the level of urea, creatinine, and potassium in your blood.
  • Avoid taking painkillers along with this medicine without consulting your doctor.
  • Lifestyle changes like a low-sodium diet, exercise, and not smoking may help this medicine work better.

Fact Box

Habit Forming
No
Therapeutic Class
CARDIAC

Patient concerns

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I am a patient of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinal condition of high blood pressure. Please see a physician.
Some times I had lot of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. ScienceDirect. Hydralazine Plus Hydrochlorothiazide Plus Reserpine. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Reserpine Pregnancy and Breastfeeding Warnings. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. Hydrochlorothiazide. Morgantown, West Virginia: Mylan Pharmaceuticals Inc.; 2011. [Accessed 10 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 10 Apr. 2019] (online) Available from:External Link
  5. Drugs.com. Hydralazine Pregnancy and Breastfeeding Warnings. [Accessed 10 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present

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