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Addbactam 2gm Injection

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Addbactam 2gm Injection is used in combination with other antibiotics for the treatment of various types of serious bacterial infections such as pneumonia, skin and soft tissue infections, urinary tract infections, and others.
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General Information

The content is shown in English
Addbactam 2gm Injection image
Addbactam 2gm Injection image

Product introduction

Addbactam 2gm Injection is a type of antibiotic belonging to a class known as beta-lactamase inhibitors. This medicine helps to make the bacteria more sensitive to antibiotic activity. It is given by drip (intravenous infusion) or by direct injection into a vein, under the supervision of a healthcare professional. It should be used regularly at evenly spaced intervals, as per the schedule prescribed by your doctor.

Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.

Before taking this medicine, inform your doctor if you have a history of an allergic reaction to this medicine or penicillin group of medicines. Diarrhea and local pain, swelling, or redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.

Uses of Addbactam Injection

  • Severe bacterial infections

Benefits of Addbactam Injection

Severe bacterial infections
Addbactam 2gm Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of lungs (pneumonia) and urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Addbactam 2gm Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Addbactam Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Addbactam
  • Injection site pain
  • Diarrhea

How to use Addbactam Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Addbactam Injection works

Addbactam 2gm Injection is a beta-lactamase inhibitor. It works by blocking an enzyme called beta lactamase produced by bacteria to inactivate antibiotics. Addbactam 2gm Injection is frequently combined with beta-lactam antibiotics, such as ampicillin, cefoperazone, meropenem. As a single medicine, it treats infection caused by a type of bacterium called Acinetobacter baumanii. This activity is mediated by its interaction with certain proteins.

All substitutes for Addbactam 2gm Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Addbactam 2gm Injection is used in treatment of severe bacterial infections, in combination with certain antibiotics. 
  • It is also used alone in the treatment of serious infections caused by pathogen Acinetobacter baumannii including those resistant to other antibiotics.
  • It is preferentially given as an injection directly into a vein over a period of 15-60 minutes.
  • When used alone, it is associated with few adverse effects, mainly pain at the injection site and diarrhea.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Addbactam 2gm Injection.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Addbactam 2gm Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

SAFE
Addbactam 2gm Injection does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Addbactam 2gm Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Addbactam 2gm Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Addbactam with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Leflunomide (Oral Route)

Do not consume Sulbactam with Leflunomide. Leflunomide may raise blood levels of Sulbactam.
Severe

Probenecid (Oral Route)

Do not consume Sulbactam with Probenecid. Probenecid may raise blood levels of Sulbactam.
Severe

Teriflunomide (Oral Route)

Do not consume Sulbactam with Teriflunomide. Teriflunomide may raise blood levels of Sulbactam.

Frequently asked questions

Addbactam 2gm Injection added to other antibiotics like ampicillin, cefoperazone, etc., because Addbactam 2gm Injection contains Sulbactam, a beta-lactamase inhibitor, which reduces resistance and enhances the activity of other antibiotics like ampicillin, cefoperazone, etc., against the bacteria.
Addbactam 2gm Injection should not be taken by an individual if he/she had an allergic reaction to ampicillin, sulbactam, or any penicillin antibiotic (such as penicillins or cephalosporins), or if he/she has a history of liver problems caused by ampicillin/sulbactam.
Before taking Addbactam 2gm Injection, you should tell your doctor if you have ever had an allergic reaction to Addbactam 2gm Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Addbactam 2gm Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Addbactam 2gm Injection.
No. You should not use Addbactam 2gm Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.
No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Addbactam 2gm Injection as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.
No. Addbactam 2gm Injection does not treat a viral infection such as the flu or a common cold.

Fact Box

Chemical Class

Alpha amino acid derivative

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Beta-Lactamase Inhibitors

Related lab tests

References

  1. Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1501.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1293-94.
  3. Sulbactam. [Accessed 28 Mar. 2019] (online) Available from:
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Fusion Healthcare Pvt Ltd
Address: Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034

Vendor Details

Country of origin: India
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