Onivyde 43mg Infusion

Pegylated Liposomal Irinotecan (43mg)

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Onivyde 43mg Infusion is a chemotherapy drug used in combination with other medications to treat metastatic pancreatic cancer, particularly in patients whose cancer has progressed after other treatments. It attacks the cancer cells and prevents them from growing and spreading.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)

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General Information

The content is shown in English

Product introduction

Onivyde 43mg Infusion is used to treat various types of cancer

Uses of Onivyde Infusion

Benefits of Onivyde Infusion

Treatment of Pancreatic cancer
Onivyde 43mg Infusion targets and kill cancer cells. This helps to slow the progression of metastatic pancreatic cancer, especially in patients whose cancer has progressed after other treatments. When combined with other chemotherapy drugs, Onivyde 43mg Infusion has been shown to improve survival rates and offer better disease control.

Side effects of Onivyde Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Onivyde

Diarrhea
Fatigue
Vomiting
Nausea
Decreased appetite
Stomatitis (Inflammation of the mouth)
Fever
Lymphopenia
Decreased white blood cell count (neutrophils)

How to use Onivyde Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Onivyde Infusion works

Onivyde 43mg Infusion is a special form of a cancer-fighting drug called Irinotecan. Irinotecan works by blocking the ability of cancer cells to divide and grow, which eventually leads to their death. It does this by targeting an enzyme called topoisomerase I, which cancer cells need to replicate their DNA. In this formulation, Irinotecan is enclosed in tiny fat-like particles called liposomes and is pegylated, meaning it’s coated with a substance (PEG) that makes it stay in the bloodstream longer. This helps the drug stay active in the body for a longer period, giving it more time to reach the cancer cells. The liposomes also help target the drug more specifically to cancer cells, reducing the side effects on healthy cells.

Quick tips

Treatment with Onivyde 43mg Infusion can lead to dehydration, especially if you experience diarrhea or vomiting. Drink plenty of water and electrolytes throughout the day to keep your body hydrated.
Onivyde 43mg Infusion is most effective when given on schedule. Make sure to attend all infusion appointments as directed by your doctor and inform them of any concerns or side effects between sessions.
Onivyde 43mg Infusion can affect your white blood cells, making you more prone to infections. Regular blood tests will be necessary to monitor your counts. Report any signs of infection (fever, chills) immediately.
Fatigue is a common side effect, but light exercise like walking can help improve energy levels and mood. Rest when needed, but aim to stay active as much as you can.
Avoid large crowds and people who are sick to reduce the risk of infection. Wash your hands frequently and practice good hygiene to keep your immune system protected.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Onivyde 43mg Infusion. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Onivyde 43mg Infusion is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Onivyde 43mg Infusion during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Onivyde 43mg Infusion may cause side effects that could affect your ability to drive.
During treatment patients should observe caution when driving or using machines.

Kidney

CAUTION

Onivyde 43mg Infusion should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, Onivyde 43mg Infusion is not recommended for use in patients with severe renal impairment.

Liver

CAUTION

Onivyde 43mg Infusion should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Onivyde 43mg Infusion used for?

Onivyde 43mg Infusion is a chemotherapy drug used to treat metastatic pancreatic cancer, particularly in patients whose cancer has continued to progress after other treatments. It is used in combination with other chemotherapy drugs.

How is Onivyde 43mg Infusion administered?

Onivyde 43mg Infusion is given as an intravenous (IV) infusion, typically every two weeks, depending on your treatment plan. It is administered by a doctor or a nurse in a hospital or clinic setting.

What should I do if I experience severe side effects?

If you experience severe diarrhea, persistent vomiting, intense abdominal pain, or symptoms of infection (such as fever), contact your doctor immediately. These could be signs of serious complications that need prompt attention.

Can I take ONIVYDE if I am pregnant or breastfeeding?

No, ONIVYDE can harm an unborn baby, so you should avoid becoming pregnant while receiving this treatment. Additionally, you should not breastfeed while on ONIVYDE, as it could pass through breast milk and harm the baby.

Are there any foods or activities I should avoid while on Onivyde 43mg Infusion?

There are no specific foods to avoid, but it is important to stay hydrated and eat a balanced diet. It is also important to avoid live vaccines (such as those for chickenpox or measles) and to stay away from people who are sick, as Onivyde 43mg Infusion can lower your immune system.

Can I receive other medications or treatments while on treatment with Onivyde 43mg Infusion?

Let your doctor know about all other medications, supplements, and treatments you are using, as some may interact with Onivyde 43mg Infusion. Always consult your doctor before starting any new medication during your treatment.

How can I reduce the risk of infections during treatment?

Since Onivyde 43mg Infusion can lower your white blood cell count, it is important to practice good hygiene, avoid close contact with sick individuals, and report any signs of infection (fever, chills, cough) to your doctor right away.

How long will I need to be on Onivyde 43mg Infusion?

The duration of your treatment depends on how well your cancer responds to Onivyde 43mg Infusion and your overall health. Your doctor will regularly monitor your progress and adjust the treatment plan as needed.

Fact Box

Chemical Class

Camptothecins

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Topoisomerase Inhibitors

Related lab tests

Carcino Embryonic Antigen

Human Papilloma Virus

Papanicolaou (PAP) Cytology

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Servier India Private Limited
Address: 1703, 17th Floor, Parinee Crescenzo, 'B' Wing, Plot No. 38 & 39 G Block behind MCA, MKC Bandra East, Mumbai 40051

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Onivyde 43mg Infusion. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Onivyde 43mg Infusion

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General Information

Contains

Salt Synonyms

Marketer

Product introduction

Uses of Onivyde Infusion

Benefits of Onivyde Infusion

Side effects of Onivyde Infusion

How to use Onivyde Infusion

How Onivyde Infusion works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Onivyde 43mg Infusion used for?

How is Onivyde 43mg Infusion administered?

What should I do if I experience severe side effects?

Can I take ONIVYDE if I am pregnant or breastfeeding?

Are there any foods or activities I should avoid while on Onivyde 43mg Infusion?

Can I receive other medications or treatments while on treatment with Onivyde 43mg Infusion?

How can I reduce the risk of infections during treatment?

How long will I need to be on Onivyde 43mg Infusion?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Carcino Embryonic Antigen

Human Papilloma Virus

Papanicolaou (PAP) Cytology

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests