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Epiduo 0.1%/2.5% Gel

Adapalene (0.1% w/w)+ Benzoyl Peroxide (2.5% w/w)

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Epiduo 0.1%/2.5% Gel is a prescription medicine that has a combination of medicines that are used to treat acne. It removes the dead layer of the skin, which is present on the top, and stops the growth of bacteria.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 07 Jan 2026 | 03:33 PM (IST)

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30 gm Gel

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Epiduo 0.1%/2.5% Gel

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₹23.0 per gm

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General Information

Contains

Adapalene (0.1% w/w)+ Benzoyl Peroxide (2.5% w/w)

Marketer

Galderma India Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Epiduo 0.1%/2.5% Gel should be used in the dose and duration as advised by your doctor. It is for external use only. Wash your hands before using this medicine. Apply only on the affected areas of the skin. It is advised to check the label for directions before use.

The most common side effects include skin irritation, itchiness, burning, and sensation at the application site. If this side effect persists for a longer duration, inform your doctor. In case by accident, this medicine goes into your eyes, ears, nose, or mouth, immediately rinse it with water.

Inform your doctor if you notice darkening discoloration or a severe burning sensation on the treated skin. Inform your doctor if you have known allergies to this medicine. If you are pregnant or breastfeeding and suffering from any other condition, please inform your doctor.

Uses of Epiduo Gel

Acne

Benefits of Epiduo Gel

Acne
Epiduo 0.1%/2.5% Gel helps treat acne by reducing the production of excessive oil in the skin. This helps keep your pores open and prevent further acne breakouts. It helps reduce redness and swelling around acne and promotes healing. It also helps reduce acne blemishes and gives you a smoother-looking skin. Epiduo 0.1%/2.5% Gel usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. This medicine will help improve your mood and uplift your confidence as acne reduces.

Side effects of Epiduo Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epiduo

Burning sensation

How to use Epiduo Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Epiduo Gel works

Epiduo 0.1%/2.5% Gel is a combination of two medicines: Adapalene and Benzoyl Peroxide, which treat acne (pimples). Adapalene is a form of vitamin A, and Benzoyl Peroxide is a keratolytic medicine. Together, they prevent the accumulation of sebum (skin’s natural oil), unblock the pores, and allow natural exfoliation of the outer layers of the skin. Benzoyl Peroxide additionally penetrates the skin and kills acne-causing bacteria.

All substitutes for Epiduo 0.1%/2.5% Gel

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Apply it to the affected area once a day at bedtime.
Epiduo 0.1%/2.5% Gel can make your skin more sensitive to sunlight. Apply sunscreen or wear protective clothing while stepping out.
Avoid getting it in your eyes or mouth. If this happens, rinse with water immediately.
Do not apply to broken, sunburnt, or sensitive areas of skin. Inform your doctor if you notice unusual dryness, redness, and peeling of the skin.
Be careful when applying Epiduo 0.1%/2.5% Gel to large areas since it can bleach hair, clothing, and furnishings upon contact.
Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Safety advice

Alcohol

No interaction found/established

Pregnancy

UNSAFE

Epiduo 0.1%/2.5% Gel is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

SAFE IF PRESCRIBED

Epiduo 0.1%/2.5% Gel may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

What are the instructions for the storage and disposal of Epiduo 0.1%/2.5% Gel?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

Can I use Epiduo 0.1%/2.5% Gel as a spot treatment (single pimple)?

It is not used for spot treatment and should not be used to treat a single pimple. Epiduo 0.1%/2.5% Gel should be applied to the entire face. Using it once daily can help treat your acne.

How long does Epiduo 0.1%/2.5% Gel take to work?

It may take up to 2-3 weeks before your symptoms improve. Epiduo 0.1%/2.5% Gel may take some time to deliver significant results. Use the medicine as directed and tell your doctor if your symptoms do not improve or if they get worse.

Fact Box

Habit Forming

Therapeutic Class

DERMA

References

User feedback

Patients taking Epiduo 0.1%/2.5% Gel

Once A Day

100%

What are you using Epiduo Gel for?

Acne

87%

Others

Dermatitis

How much was the improvement?

Average

55%

Excellent

41%

Poor

What were the side-effects while using Epiduo 0.1%/2.5% Gel?

No Side Effect

60%

Skin peeling

20%

Erythema (skin redness)

10%

Dry skin

10%

How do you take Epiduo Gel?

With or without food

70%

With food

30%

Please rate Epiduo 0.1%/2.5% Gel on price

Expensive

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Galderma India Pvt Ltd
Address: Lotus Corporate Park, D Wing Unit 801\802 , Off Western Express Highway, Goregaon (East), Mumbai 400 063, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Epiduo 0.1%/2.5% Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Epiduo 0.1%/2.5% Gel

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Epiduo Gel

Benefits of Epiduo Gel

Side effects of Epiduo Gel

How to use Epiduo Gel

How Epiduo Gel works

All substitutes for Epiduo 0.1%/2.5% Gel

Minoz-BPO Gel

Peroduo Gel

Persol PLUS Gel

aDApero Gel

Benzadaf Gel

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What are the instructions for the storage and disposal of Epiduo 0.1%/2.5% Gel?

Can I use Epiduo 0.1%/2.5% Gel as a spot treatment (single pimple)?

How long does Epiduo 0.1%/2.5% Gel take to work?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Epiduo 0.1%/2.5% Gel

What are you using Epiduo Gel for?

How much was the improvement?

What were the side-effects while using Epiduo 0.1%/2.5% Gel?

How do you take Epiduo Gel?

Please rate Epiduo 0.1%/2.5% Gel on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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