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MBA, MD Pharmacology
Last updated
11 Jun 2025 | 08:10 PM (IST)

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Delvosteron 40mg Injection

Prescription Required

Product introduction

Delvosteron 40mg Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux and some other stomach conditions associated with excessive acid production.

Delvosteron 40mg Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Additionally, your doctor will decide the duration of treatment. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.

The most common side effects observed with this medicine include injection site reactions, nausea, headache, dizziness, flatulence, diarrhea, stomach pain, and fundic gland polyps. These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.

Delvosteron 40mg Injection is not suitable for some people. Before receiving this injection, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor. Avoid drinking alcohol as it can make your stomach produce excessive acid and may worsen your symptoms.


Uses of Delvosteron Injection


Side effects of Delvosteron Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Delvosteron

  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Headache
  • Flatulence
  • Injection site reaction
  • Nausea
  • Fundic gland polyps

How to use Delvosteron Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Delvosteron Injection works

Delvosteron 40mg Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Delvosteron 40mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Delvosteron 40mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Delvosteron 40mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Delvosteron 40mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Delvosteron 40mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Delvosteron 40mg Injection may be needed. Please consult your doctor.
Dose adjustment is not required in patients with mild to moderate kidney disease.
Liver
CAUTION
Delvosteron 40mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Delvosteron 40mg Injection may be needed. Please consult your doctor.
Dose adjustment is not required in patients with mild to moderate liver disease.

What if you forget to take Delvosteron Injection?

If you miss a dose of Delvosteron 40mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Delvosteron 40mg Injection
₹107/Injection
Raciper IV Injection
Sun Pharmaceutical Industries Ltd
₹95.5/injection
14% cheaper
Nexpro IV Injection
Torrent Pharmaceuticals Ltd
₹164/injection
48% costlier
Sompraz 40mg Injection
Sun Pharmaceutical Industries Ltd
₹104/injection
6% cheaper
Esoz 40mg Injection
Integrace Pvt Ltd
₹188/injection
70% costlier
Esoprz 40mg Injection
Zyphar's Pharmaceuticals Pvt Ltd
₹68.57/injection
38% cheaper

Quick tips

  • It is given as an injection into a vein under the supervision of the doctor.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Long-term use of Delvosteron 40mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
  • Delvosteron 40mg Injection should be taken 1 hour before a meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use of Delvosteron 40mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Fact Box

Chemical Class
Sulfinylbenzimidazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors

Interaction with drugs

Taking Delvosteron with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Do not consume Erlotinib with Esomeprazole. Esomeprazole may reduce blood levels of Erlotinib.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

Patient concerns

Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often
Dr. Vijay Verma
ENT
it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

FAQs

Can I take antacids along with Delvosteron 40mg Injection?

Yes, you can take antacids along with Delvosteron 40mg Injection. Take it 2 hours before or after you receive Delvosteron 40mg Injection.

What dietary changes should I make to get relief from acidity?

Delvosteron 40mg Injection is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. You must refrain from caffeinated drinks such as tea, coffee, and cola. Alcohol intake should also be avoided as it may worsen your symptoms.

Are painkillers safe to take along with Delvosteron 40mg Injection?

Yes, it is safe to take painkillers along with Delvosteron 40mg Injection. Delvosteron 40mg Injection prevents acidity and stomach ulcers associated with the intake of painkillers. Delvosteron 40mg Injection is taken 1 hour before a meal. On the other hand, painkillers are usually taken with, or after a meal to avoid stomach upset.

What is the best time to take Delvosteron 40mg Injection?

Usually, Delvosteron 40mg Injection is taken once a day, first thing in the morning. If you take Delvosteron 40mg Injection twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.

Can I take antacids along with Delvosteron 40mg Injection?

Yes, you can take antacids along with Delvosteron 40mg Injection. Take it 2 hours before or after you take Delvosteron 40mg Injection.

Can I take Delvosteron 40mg Injection with domperidone?

Yes, Delvosteron 40mg Injection can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Delvosteron 40mg Injection decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Can I take Delvosteron 40mg Injection for a long term?

Delvosteron 40mg Injection is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Delvosteron 40mg Injection may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Delvosteron 40mg Injection as advised by your doctor and under their supervision.

Can I stop taking Delvosteron 40mg Injection if I feel better?

If you have been taking Delvosteron 40mg Injection for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Delvosteron 40mg Injection.

Can Delvosteron 40mg Injection cause weight gain?

Weight gain is reported in less than 1% of the patients taking Delvosteron 40mg Injection but the exact cause is unknown. One possible explanation is higher food intake once the reflux symptoms are relieved. Lifestyle modifications such as proper diet and exercise can help to prevent weight gain.

Is Delvosteron 40mg Injection safe to use?

Yes, Delvosteron 40mg Injection is relatively safe to use. Most of the people who take Delvosteron 40mg Injection do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefit.

What are the long term side effects of Delvosteron 40mg Injection?

If Delvosteron 40mg Injection is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.

Can I take Delvosteron 40mg Injection with ranitidine?

Yes, Delvosteron 40mg Injection can be taken with ranitidine. According to research reports, there are no significant interactions seen between Delvosteron 40mg Injection and ranitidine. However, you must take them together only if prescribed by the doctor.

Can I take alcohol with Delvosteron 40mg Injection?

No, alcohol intake is not advised with Delvosteron 40mg Injection. Alcohol itself does not affect the working of Delvosteron 40mg Injection, but it can increase the acid production. This may further cause worsening of your symptoms

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References

  1. Esomeprazole sodium [FDA Label]. Wilmington, DE: AstraZeneca LP; 2012. [Accessed 24 Apr. 2020] (online) Available from: External Link
  2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Esomeprazole. [Updated 2019 Jun 3]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Esomeprazole sodium [Prescribing Information]. Wilmington, DE: AstraZeneca; 2022. [Accessed 22 Jun. 2023] (online) Available from:External Link

Marketer details

Name: MSD Pharmaceuticals Pvt Ltd
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Country of origin: India
Expires on or after: September, 2025

A licensed vendor partner from your nearest location will deliver Delvosteron 40mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
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