
Selenium, Serum by ICPMS







The Selenium, Serum by ICPMS test is used to measure the amount of selenium in the blood. Selenium is an essential trace mineral that acts as a powerful antioxidant and supports thyroid hormone metabolism, immune function, and DNA synthesis. This test helps evaluate and monitor selenium status, nutritional imbalances, and conditions affecting thyroid or immune system health.













Understanding Selenium, Serum by ICPMS
Selenium is a vital micronutrient required in small amounts for maintaining overall health. It plays a crucial role in the formation of selenoproteins and enzymes that regulate antioxidant defense, thyroid function, and reproductive health. Selenium also helps in protecting cells from oxidative damage and supports the immune system.
Both selenium deficiency and excess can cause health issues. Deficiency may lead to weakened immunity, thyroid dysfunction, fertility problems, muscle weakness, or cognitive decline, while excess selenium (selenosis) can cause nausea, hair and nail brittleness, skin rashes, and in severe cases, nervous system damage. The Selenium, Serum by ICPMS test helps check whether the selenium levels in the body are within the healthy range, ensuring early detection and management of any imbalance.
The Selenium, Serum by ICPMS test may be advised when there are symptoms suggestive of selenium imbalance in the body, such as fatigue, muscle weakness, hair loss, brittle nails, or cognitive difficulties. The test is particularly relevant for individuals who have limited access to selenium-rich foods, such as people with malabsorption disorders or those on long-term parenteral nutrition. It is also important for individuals who live in regions where the soil is low in selenium, as the amount of selenium in local food sources may be insufficient. Additionally, this test may be used to monitor individuals taking selenium supplements or those undergoing treatments for conditions that affect selenium metabolism or absorption.
For this test, it is advised to avoid herbal supplements for at least 3 days before sample collection, and the test should not be taken within 96 hours after imaging procedures that use gadolinium or iodine-based contrast media, as these may interfere with the results.
Test result ranges may vary across laboratories. Abnormal test results require expert interpretation. Therefore, self-medicating at home based solely on these results should be avoided. Always consult a doctor for a proper understanding of the test results.
Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at an NABL accredited partnered lab.
What does Selenium, Serum by ICPMS measure?
The Selenium, Serum by ICPMS test measures the concentration of selenium in the blood. Selenium is a trace mineral essential for antioxidant protection, thyroid hormone regulation, reproductive health, and immune function. The results indicate whether selenium levels are within the normal range, too low, or too high.
Low selenium levels may point to dietary deficiency, poor absorption due to gastrointestinal issues, or increased metabolic demands, leading to problems such as impaired immunity, thyroid dysfunction, or reproductive health concerns. High selenium levels may suggest over-supplementation, dietary excess, or exposure to toxic levels, which can cause hair and nail brittleness, skin rashes, digestive upset, and neurological issues.
This test is performed using advanced techniques such as inductively coupled plasma mass spectrometry (ICP-MS), which enables precise measurement of trace elements in body fluids. Detecting abnormal selenium levels helps doctors identify underlying conditions, guide nutritional or medical treatment, and monitor therapy in individuals at risk of selenium imbalance.





FAQs related to Selenium, Serum by ICPMS
- Selenium [Internet]. NHS; 15 Apr. 2024 [Accessed 01 Sep. 2025]. Available from:
- Shreenath AP, Hashmi MF, Dooley J. Selenium Deficiency. [Updated 2023 Oct 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from:
- MacFarquhar JK, Broussard DL, Melstrom P, Hutchinson R, Wolkin A, Martin C, Burk RF, Dunn JR, Green AL, Hammond R, Schaffner W, Jones TF. Acute selenium toxicity associated with a dietary supplement. Arch Intern Med. 2010 Feb 8;170(3):256-61. [Accessed 01 Sep. 2025]. Available from:
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