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Understanding the Test
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PTH (Intact Parathyroid Hormone)

Also known as Parathormone, intact PTH
14891600 6% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. Overnight fasting (8-12 hrs) is required. Do not eat or drink anything except water before the test.

Understanding PTH (Intact Parathyroid Hormone)


What is PTH (Intact Parathyroid Hormone)?

The PTH (Intact Parathyroid Hormone) test assesses the level of parathyroid hormone (PTH) that plays a crucial role in regulating calcium and phosphorus levels in the body. This test helps evaluate parathyroid gland function and primarily diagnose conditions related to calcium imbalance.

Parathyroid hormone (PTH) is produced by the parathyroid glands, four small glands located near the thyroid gland in the neck. PTH plays an important role in regulating the levels of calcium and phosphorus in the body. It helps maintain calcium balance by influencing its absorption from the intestines, release from bones, and reabsorption by the kidneys. PTH ensures that the concentration of calcium in the blood stays within a normal range as it is essential for various physiological functions, including bone health, nerve transmission, and muscle contraction. 

A PTH (Intact Parathyroid Hormone) test helps in assessing the function of the parathyroid gland and identifying conditions associated with imbalances in calcium and, to some extent, phosphorus. Understanding PTH levels can provide valuable insights into bone health, kidney function, and disorders related to mineral metabolism. Regular monitoring of PTH levels is essential for individuals with conditions affecting calcium homeostasis and those at risk of bone disorders or kidney problems. Additionally, this test can be done when individuals exhibit symptoms related to calcium and phosphorus imbalance, such as persistent bone pain, impaired kidney function, long-term digestive problems, pain or discomfort in joints, muscle weakness, etc. Also, it can be done when your routine blood tests show abnormal calcium or phosphorus levels. These symptoms may indicate disorders such as hypoparathyroidism or hyperparathyroidism, where parathyroid glands are either underactive or overactive, respectively.

Overnight fasting for at least 8-12 hours is needed before undertaking the PTH (Intact Parathyroid Hormone) test. However, drinking water before the test is acceptable. PTH is released in a rhythmic pattern, with increased levels during the night; therefore, you may need to take the test at a certain time of day. Also, tell your doctor about all the medications or supplements, including calcium, that you are taking before undertaking this test, as these may interfere with the test results.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. The insights from PTH (Intact Parathyroid Hormone)  test help the doctor tailor a treatment plan to address specific problems like hypoparathyroidism or hyperparathyroidism and target to restore calcium balance in the body.

What is PTH (Intact Parathyroid Hormone) used for?

A PTH (Intact Parathyroid Hormone) test is done: 

  • To evaluate parathyroid gland function.

  • To diagnose conditions associated with calcium imbalance.

  • To diagnose and monitor disorders like hypoparathyroidism or hyperparathyroidism.

  • To monitor patients with chronic kidney disease.

  • To assess bone health and risk of osteoporosis.

  • To determine the effectiveness of ongoing treatment for parathyroid disorders.

  • To monitor surgical treatment for hyperparathyroidism. 

What does PTH (Intact Parathyroid Hormone) measure?

A PTH (Intact Parathyroid Hormone) test measures the levels of parathyroid hormone (PTH) in the blood. PTH regulates calcium and phosphorus levels in the body. PTH levels are regulated by a feedback loop with calcium in the blood. Low calcium stimulates PTH release, and high calcium inhibits it. Problems like tumors or damage to the parathyroid glands can disrupt this balance, leading to abnormal PTH levels.

Monitoring of PTH levels is important in managing disorders affecting bone and mineral metabolism, and PTH (Intact Parathyroid Hormone) test helps assess the function of parathyroid glands and diagnose conditions related to calcium and phosphorus imbalance.

Interpreting PTH (Intact Parathyroid Hormone) results


Interpretations

Normal range: 14.00 to 72.00 pg/ml

Reference ranges may vary in different labs.

An Intact Parathyroid Hormone Test is performed together with a Blood Calcium Test to determine the cause of calcium deficiency, and the results are interpreted as follows:

Calcium

PTH

Interpretation

Normal

Normal

Blood calcium regulation normal

Low

High

Parathyroid gland normal, low Calcium levels are due to other causes

Low

Normal/Low

PTH secretion low, hypoparathyroidism may be indicated

High

High

Hyperparathyroidism may be indicated

High

Low

Parathyroid gland normal, high Calcium levels are due to other causes

Normal

High

Mild hyperparathyroidism

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about PTH (Intact Parathyroid Hormone)


Frequently Asked Questions about PTH (Intact Parathyroid Hormone)

Q. Why is a PTH (Intact Parathyroid Hormone) test done?

A PTH (Intact Parathyroid Hormone) test is done to assess parathyroid gland function and detect conditions related to calcium imbalance.

Q. Is fasting required before taking the PTH (Intact Parathyroid Hormone) test?

Yes, overnight fasting of 8 to 12 hours is needed before undertaking PTH (Intact Parathyroid Hormone) test. However, drinking water is acceptable.

Q. Can calcium supplements interfere with PTH (Intact Parathyroid Hormone) test results?

Yes, calcium supplements can affect parathyroid hormone levels; therefore, it is important to inform your doctor about any supplements you are taking before going for a PTH (Intact Parathyroid Hormone) test.

Q. What are the most common causes of low parathyroid hormone levels?

The most common causes of low parathyroid hormone levels include reduced activity of parathyroid glands, increased hormone secretion from the thyroid gland (hyperthyroidism), deficiency of magnesium, and hypercalcemia unrelated to the parathyroid gland.

Q. What are the most common causes of high parathyroid hormone levels?

The most common causes of high parathyroid hormone levels include parathyroid gland tumors, improper response of the kidneys to PTH, deficiency of Vitamin D, injury to the spinal cord, hypocalcemia unrelated to parathyroid gland.

Q. How does vitamin D affect PTH levels?

Vitamin D helps the body absorb calcium from food. If your body does not get enough vitamin D, PTH levels can rise, leading to hyperparathyroidism.

Q. What is an intraoperative PTH test?

An Intraoperative PTH test assesses the intact parathyroid hormone levels during surgery to ensure complete removal of abnormal parathyroid gland tissues.

Q. What additional tests can be prescribed by your doctor if the results of a PTH (Intact Parathyroid Hormone) test are abnormal?

Additional tests that may be prescribed in case of abnormal parathyroid hormone test results are blood calcium test, electrolyte panel test, and kidney function tests.
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PTH (Intact Parathyroid Hormone) test price for other cities


Price inMumbaiRs. 1489
Price inGurgaonRs. 1489
Price inBangaloreRs. 1489
Price inKolkataRs. 1489
Price inHyderabadRs. 1489
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References

  1. Khan M, Jose A, Sharma S. Physiology, Parathyroid Hormone. [Updated 2022 Oct 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK499940/ External Link
  2. Parathyroid Hormone [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 15 Dec. 2023]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=parathyroid_hormone External Link
  3. Primary Parathyroidism. [Internet]. NIH; Mar. 2019. [Accessed 15 Dec. 2023]. Available from: https://www.niddk.nih.gov/health-information/endocrine-diseases/primary-hyperparathyroidism External Link
  4. Hyperparathyroidism. [Internet]. NHS; 24 May. 2021 [Accessed 15 Dec. 2023]. Available from: https://www.nhs.uk/conditions/hyperparathyroidism/ External Link
  5. Hans SK, Levine SN. Hypoparathyroidism. [Updated 2022 May 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441899/ External Link
  6. Hypoparathyroidism. [Internet]. NHS; 01 Apr. 2021 [Accessed 15 Dec. 2023]. Available from: https://www.nhs.uk/conditions/hypoparathyroidism/ External Link
  7. Silva BC, Bilezikian JP. Parathyroid hormone: anabolic and catabolic actions on the skeleton. Curr Opin Pharmacol. 2015 Jun;22:41-50. [Accessed 15 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407089/#:~:text=Parathyroid%20hormone%20(PTH)%20is%20an,the%20gastrointestinal%20tract%20%5B1%5D. External Link
  8. Medas F, Erdas E, Loi G, Podda F, Barca L, Pisano G, Calò PG. Intraoperative parathyroid hormone (PTH) testing in patients with primary hyperparathyroidism and PTH levels in the normal range. BMC Surg. 2019 Apr 24;18(Suppl 1):124. [Accessed 15 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402568/ External Link
  9. Dawale K, Agrawal A. Parathyroid Hormone Secretion and Related Syndromes. Cureus. 2022 Oct 13;14(10):e30251. [Accessed 15 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650928/ External Link

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