Neuronal Antibody Profile - 1

Paraneoplastic syndromes are uncommon conditions that can develop in people with cancer. They are not caused by the tumor spreading but by the body’s reaction to the cancer. This may happen when cancer cells release certain chemicals or when the immune system mistakenly attacks healthy tissues. These syndromes can affect different organs, including the nerves, skin, blood, or the hormone system. In some cases, they may even appear before the cancer is diagnosed, giving doctors an early clue about the illness.

The Neuronal Antibody Profile - 1 checks for antibodies that attack certain nerve proteins, such as amphiphysin, PNMA2, CV2, Hu, Ri, and Yo. If these antibodies are found, it can help doctors support the diagnosis of paraneoplastic syndromes and guide evaluation for underlying cancers like lung, breast, or ovarian cancer.

Doctors may recommend the Neuronal Antibody Profile - 1 if there are possible symptoms such as muscle weakness, seizures, changes in mood or behavior (like anxiety, depression, confusion, or hallucinations), vision problems, or difficulty with walking and movement. The test is done using specialized laboratory methods to detect IgG antibodies in the blood.

No special preparation is needed, but it is important to inform the doctor about any medicines being taken or if the patient is pregnant, as it may be relevant for interpretation.

Test result ranges can vary slightly between laboratories, depending on their methods and standards. The report should not be interpreted without medical guidance. It is advisable to consult the doctor, who will explain the results in the context of the individual’s symptoms and other investigations.

 Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.