MPN Panel 3 near me in Mumbai

The MPN Panel 3 detects important genetic mutations and gene fusions that help diagnose and classify myeloproliferative neoplasms (MPNs). This includes CALR mutations, JAK2 mutations (exons 12–15), MPL mutations, and the BCR-ABL1 fusion, which is essential for identifying chronic myeloid leukemia (CML). By analyzing these mutations and fusions, the test provides a comprehensive genetic profile, enabling doctors to accurately diagnose, classify, and manage both BCR-ABL1–positive and BCR-ABL1–negative MPNs. 

Abnormal results may indicate the presence of specific MPNs: BCR-ABL1 fusion may suggest CML, JAK2 mutations may indicate polycythemia vera (PV) or essential thrombocythemia (ET), and CALR or MPL mutations may point to primary myelofibrosis (PMF). Further evaluation and consultation with a hematologist are necessary for accurate diagnosis and appropriate treatment.