GAD-65 AntibodyType I Diabetes

The GAD enzyme is involved in the production of the neurotransmitter gamma-aminobutyric acid (GABA), which is important for the proper functioning of the insulin-producing islet cells in the pancreas. These antibodies can show up in the blood years before the onset of clinical symptoms of type 1 diabetes, making this test a useful marker for identifying individuals who may be more likely to develop the disease.

In type 1 diabetes, the immune system mistakenly targets the GAD enzyme and produces antibodies against it. Detecting these antibodies early can help with early treatment, allowing for better management of the condition and potentially delaying the onset of severe symptoms associated with type 1 diabetes.

This test is recommended for people with diabetes symptoms like frequent urination, thirst, tiredness, weight loss, or numbness in the hands or feet. It is also useful if the individual has a family history of type 1 diabetes or autoimmune diseases. Additionally, this test is useful for differentiating between type 1 and type 2 diabetes, as well as aiding in the diagnosis of other autoimmune diseases such as autoimmune polyendocrine syndrome type 1 (APS-1), stiff-person syndrome, cerebellar ataxia, epilepsy, seizures and paraneoplastic neurological syndromes..

No special preparation is needed for the GAD-65 AntibodyType I Diabetes. However, let the doctor know about any medications, supplements, or health conditions, as they might affect the results. 

Lab test results may vary across laboratories. Abnormal test results require an expert interpretation. Therefore, don't self-medicate at home solely based on these results. Always consult a doctor for a proper understanding of the test results.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.