
Fecal Elastase, Stool










The Fecal Elastase, Stool test is a noninvasive stool test used to assess the ability of the pancreas to produce an adequate amount of pancreatic elastase enzyme. This test helps diagnose conditions such as chronic pancreatitis, cystic fibrosis, or pancreatic insufficiency.













Understanding Fecal Elastase, Stool
Pancreatic elastase is an enzyme produced by the pancreas to help digest food (proteins). Since elastase remains stable as it passes through the gastrointestinal tract, its levels in the stool directly reflect pancreatic output.
This test is especially useful for diagnosing exocrine pancreatic insufficiency (EPI), where the pancreas does not release enough digestive enzymes. EPI can occur due to conditions such as chronic pancreatitis, cystic fibrosis, diabetes, or pancreatic cancer. Individuals may experience symptoms like bloating, unexplained weight loss, diarrhea, and greasy or foul-smelling stools.
Doctors may suggest the Fecal Elastase, Stool test when a patient presents with signs of poor digestion or malabsorption. It is a convenient and reliable screening test to guide further diagnostic and treatment steps.
For this test, collect a fresh stool sample in a clean, sterile, leak-proof screw-capped container, preferably one with a spoon. Only a small portion of about 5–10 grams (1–2 teaspoons) is needed, so avoid overfilling the container. Do not use matchboxes, paper, or other absorbent materials for collection, and ensure the sample is not contaminated with urine or water. Please also provide your doctor with a history of any medications you are taking, as these may affect the test results.
Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly.
Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.
What does Fecal Elastase, Stool measure?
The Fecal Elastase, Stool test measures the concentration of the elastase enzyme in a stool sample. Elastase is produced by the pancreas and helps in breaking down proteins in food. A low level of pancreatic elastase in stool is indicative of reduced enzyme production and points to exocrine pancreatic insufficiency (EPI), which can impair nutrient absorption. Normal levels suggest adequate pancreatic function.





FAQs related to Fecal Elastase, Stool
- Pancreatic Elastase [Internet]. ScienceDirect; [Accessed 10 Jul. 2025]. Available from:
- Hamwi A, Veitl M, Maenner G, Vogelsang H, Szekeres T. Pancreatic elastase 1 in stool: variations within one stool passage and individual changes from day to day. Wien Klin Wochenschr. 2000 Jan 14;112(1):32-5. PMID: 10689738. [Accessed 10 Jul. 2025]. Available from:
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