Calprotectin, Stool

Fecal matter/stool can provide important information about conditions affecting your gut or gastrointestinal (GI) tract. The Calprotectin, Stool test is a non-invasive biomarker that allows the evaluation of intestinal inflammation caused by conditions like inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, and differentiates it from other non-inflammatory diseases, such as irritable bowel syndrome (IBS). Fecal Calprotectin may also be associated with other disorders such as celiac disease, colorectal cancer, and gastrointestinal infections, which also show inflammation of the gut.

The Calprotectin, Stool test can help differentiate between inflammatory and non-inflammatory bowel conditions. Higher than normal amounts of fecal calprotectin are usually associated with active inflammatory diseases, while lower levels indicate other non-inflammatory conditions. Additionally, this test can be used to monitor the effectiveness of ongoing treatment for IBD, look for recurrence or relapse, and adjust treatment plans accordingly. This test can also help determine whether an endoscopy is indicated if IBD is suspected. 

Your doctor may suggest getting the Calprotectin, Stool test if you notice symptoms of IBD, such as chronic diarrhea, abdominal pain, rectal bleeding, weight loss, and fatigue. The test is not a specific or diagnostic test for IBD but may help evaluate the degree of inflammation. It should be noted that additional blood and stool tests may be performed if the doctor suspects certain conditions that might be causing the symptoms.

For this test, collect a fresh stool sample in a clean, sterile, leak-proof screw-capped container, preferably one with a spoon. Only a small portion of about 5–10 grams (1–2 teaspoons) is needed, so avoid overfilling the container. Do not use matchboxes, paper, or other absorbent materials for collection, and ensure the sample is not contaminated with urine or water. The stool sample should not be submitted during menstrual bleeding or if the stool contains visible blood. Use of NSAIDs or antibiotics may also affect the results, so it is important to inform your doctor about any medications you are currently taking.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The results will help them determine your medical condition and formulate your treatment plan.

Please note : This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.