Factor V Leiden Mutant Detection (G1691A Mutation)

Factor V is a protein that plays a central role in blood clotting. Normally, activated protein C regulates clot formation by inactivating factor V to prevent excessive clotting. However, a mutation in the factor V Leiden gene (G1691A) makes the factor V protein resistant to being inactivated, which can lead to a higher risk of developing abnormal blood clots, such as deep vein thrombosis (DVT) or venous thromboembolism (VTE).

Identifying the presence of the Factor V Leiden mutation is important because it helps explain why some individuals are more prone to abnormal clotting. 

The Factor V Leiden Mutant Detection (G1691A Mutation) test is especially useful for individuals with unexplained or recurrent episodes of blood clots, including deep vein thrombosis (DVT) or venous thromboembolism (VTE). It is recommended for patients with a personal or family history of the factor V Leiden mutation or those with a family background of blood-clotting disorders. Women experiencing recurrent miscarriages or pregnancy complications linked to abnormal clotting may also benefit from this test, as the mutation can contribute to pregnancy loss. In addition, it is valuable in cases of clinically suspected thrombophilia, where an inherited gene mutation may increase the risk of abnormal clot formation. By identifying whether a person carries the factor V Leiden mutation, doctors can assess the risk of thrombosis and guide appropriate preventive measures and treatment strategies.

No special preparation is needed for getting the Factor V Leiden Mutant Detection (G1691A Mutation) test done. However, it is preferred that you share your clinical history, current medications, and supplement use with your doctor before giving the sample, as these may influence the results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate, and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.