Estriol Unconjugated

Also referred as

Unconjugated Estriol

Serum

Pregnancy

For men & women

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72 hours

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1 test

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₹1259

~~₹1400~~

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The Estriol Unconjugated test is a blood test used to measure the levels of the unconjugated estriol, a hormone produced by the placenta during pregnancy. It helps assess the well-being of the fetus and monitor pregnancy health.

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Blood

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Understanding Estriol Unconjugated

The Estriol Unconjugated test is often done as a part of the triple or quadruple screening test conducted during the second trimester of pregnancy. This test analyzes a specific marker called unconjugated estriol (uE3), a form of estrogen produced by the fetoplacental unit during pregnancy.Estriol plays an important role in maintaining pregnancy by supporting the growth and development of the unborn child.

By measuring the levels of unconjugated estriol, doctors can assess the unborn child's well-being and the overall pregnancy. Abnormal levels of unconjugated estriol, done as part of the pre-natal screening tests may indicate certain fetal abnormalities or complications, such as Down syndrome (trisomy 21), trisomy 18, or other chromosomal abnormalities. Timely detection of these abnormalities is vital for ensuring comprehensive prenatal care and addressing potential health problems effectively.

The Estriol Unconjugated test is a screening test, and any abnormal result does not necessarily mean that the unborn baby has a birth defect or genetic condition. It only tells whether the unborn baby is at risk of developing certain abnormalities, and further testing is required to confirm the diagnosis. The decision to recommend the Estriol Unconjugated test is often based on maternal age, medical history, and individual risk factors for chromosomal abnormalities. Pregnant women should consult their doctor to determine the most appropriate screening or diagnostic test based on their specific conditions.

No special preparation is required before undergoing a Estriol Unconjugated test. However, a woman needs to be prepared to provide informed consent before undertaking this test. The laboratory personnel will explain the purpose, benefits, and limitations of this test.

Abnormal lab test results represent only the risk but not the diagnostic outcomes. Increased risk does not mean that the baby is affected, and further tests must be performed before a confirmed diagnosis can be made. Talk to the doctor about the specific test results. The results of the Estriol Unconjugated test, along with a woman's clinical symptoms and other factors, can help doctors detect and manage pregnancy-related abnormalities and make informed decisions regarding further testing or interventions.

What does Estriol Unconjugated measure?

The Estriol Unconjugated test is used to assess the level of unconjugated estriol (uE3) in the blood, a specific type of estrogen produced during the pregnancy phase. This hormone is mainly synthesized in the placenta and the fetus, with the fetus being responsible for a substantial amount of uE3 production as it grows.

Monitoring the uE3 levels in the maternal serum is useful in evaluating the condition of the fetus. Abnormal unconjugated estriol levels may indicate pregnancy-related complications or concerns, including chromosomal abnormalities, fetal distress, or placental problems. The Estriol Unconjugated is particularly crucial in the second trimester to assess for some conditions, such as Down syndrome, Edward syndrome, or other chromosomal abnormalities, fetal growth and development. Hence the estriol unconjugated test is a significant part of prenatal care as it reveals information that may be valuable for the diagnosis and management of the mother and the baby.

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Test Information is reviewed by: Dr. Swati Gupta (Anand), MD Lab Medicine, MBBS and written by Dr. Lipika Khurana, BDS, PGDHHM . The test details are for information purpose only. Consult a doctor before taking any test. Last updated on: 8th Oct 2026

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Estriol Unconjugated test price for other cities

Price in	Bangalore	Rs. 1209
Price in	Mumbai	Rs. 1079
Price in	Prayagraj	Rs. 1319
Price in	Jaipur	Rs. 1260
Price in	Noida	Rs. 1330

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FAQs related to Estriol Unconjugated

What is the purpose of the Estriol Unconjugated test?

The Estriol Unconjugated test measures the amount of unconjugated estriol (a hormone produced in women during pregnancy). The purpose of this test is to assess the health of the fetus, especially in conjunction with other tests, as part of prenatal screening for certain conditions like Down syndrome or Edward syndrome.

When should I have the estriol unconjugated test done?

The Estriol Unconjugated test is typically done between the 14-22 weeks of gestation (ideal 15-20 weeks) of pregnancy as part of the second-trimester screening, such as the quadruple or triple screen.

How is the test performed?

A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.

What should I do if my uE3 levels are abnormal?

If your uE3 levels are abnormal, it's important to consult your doctor to discuss the Estriol Unconjugated results and understand what they mean. Your doctor may suggest further testing based on your results and overall health.

Is the Estriol Unconjugated test safe?

Yes, this is non-invasive and safe for both the mother and the baby. It simply involves drawing a small sample of blood.

Are there any special preparations I need to follow before the test?

No special preparation is needed for the Estriol Unconjugated test. However, do not forget to follow any specific instructions provided by your doctor regarding the test.

Is it mandatory to have this test during pregnancy?

No, the Estriol Unconjugated test is not mandatory during pregnancy. However, it is commonly recommended as part of routine prenatal screening to monitor the health of the fetus.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

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